Patents by Inventor Mark Rosowski

Mark Rosowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of preparing an artificial tooth primordium in vitro and artificial tooth primordium derived therefrom
    Patent number: 11578308
    Abstract: The present invention is directed to a method of preparing an artificial tooth primordium in vitro, comprising the steps: a) providing isolated mesenchymal dental pulp cells; and b) culturing the mesenchymal dental pulp cells under non-adherent conditions to form a cell aggregate representing an artificial tooth primordium; as well as to an artificial tooth primordium derived therefrom.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: February 14, 2023
    Assignee: TECHNISCHE UNIVERSITAET BERLIN
    Inventors: Roland Lauster, Uwe Marx, Jennifer Binder, Mark Rosowski
  • METHOD OF PREPARING AN ARTIFICIAL TOOTH PRIMORDIUM IN VITRO AND ARTIFICIAL TOOTH PRIMORDIUM DERIVED THEREFROM
    Publication number: 20190185815
    Abstract: The present invention is directed to a method of preparing an artificial tooth primordium in vitro, comprising the steps: a) providing isolated mesenchymal dental pulp cells; and b) culturing the mesenchymal dental pulp cells under non-adherent conditions to form a cell aggregate representing an artificial tooth primordium; as well as to an artificial tooth primordium derived therefrom.
    Type: Application
    Filed: January 18, 2019
    Publication date: June 20, 2019
    Inventors: Roland LAUSTER, Uwe MARX, Jennifer BINDER, Mark ROSOWSKI
  • 3D in vitro bi-phasic cartilage-bone construct
    Patent number: 9856458
    Abstract: A 3D in vitro bi-phasic cartilage-bone organoid includes a layer of an artificial cartilage tissue, and a layer of an artificial bone tissue comprising a structure-giving scaffold and a bone marrow structure. The layer of the artificial cartilage tissue contacts at least one surface of the layer of the artificial bone tissue.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: January 2, 2018
    Assignee: TISSUSE GMBH
    Inventors: Mark Rosowski, Shirin Kadler, Roland Lauster, Uwe Marx
  • 3D IN VITRO BI-PHASIC CARTILAGE-BONE CONSTRUCT
    Publication number: 20150093428
    Abstract: A 3D in vitro bi-phasic cartilage-bone organoid includes a layer of an artificial cartilage tissue, and a layer of an artificial bone tissue comprising a structure-giving scaffold and a bone marrow structure. The layer of the artificial cartilage tissue contacts at least one surface of the layer of the artificial bone tissue.
    Type: Application
    Filed: February 28, 2013
    Publication date: April 2, 2015
    Applicant: TISSUSE GMBH
    Inventors: Mark Rosowski, Shirin Fatehi-Varkani, Roland Lauster, Uwe Marx
  • METHOD OF PREPARING AN ARTIFICIAL TOOTH PRIMORDIUM IN VITRO AND ARTIFICIALTOOTH PRIMORDIUM DERIVED THEREFROM
    Publication number: 20140377233
    Abstract: The present invention is directed to a method of preparing an artificial tooth primordium in vitro, comprising the steps: a) providing isolated mesenchymal dental pulp cells; and b) culturing the mesenchymal dental pulp cells under non-adherent conditions to form a cell aggregate representing an artificial tooth primordium; as well as to an artificial tooth primordium derived therefrom.
    Type: Application
    Filed: February 20, 2013
    Publication date: December 25, 2014
    Inventors: Roland Lauster, Uwe Marx, Jennifer Binder, Mark Rosowski