Abstract: A method of determining a personalised therapeutic regime, comprising: receiving genetic information relating to a patient; determining genetic criteria relevant to a personalised therapeutic regime for the patient using the genetic information; receiving personal information relating to the patient; determining personal criteria relevant to the personalised therapeutic regime using the personal information; and combining the genetic criteria and the personal criteria to determine the personalised therapeutic regime for the patient.

Abstract: A one stage process for the preparation reservoir patches comprises feeding webs to a first pair of sealing rollers and, thence, directly to a second pair of die-cutting rollers, and in certain embodiments, directly into a packaging step, thereby avoiding most operator-related error, and substantially increasing overall sterility and reproducibility

Abstract: A continuous process for forming a transdermal patch which comprises the steps of: continuously feeding a strip of material comprising a layer of permeable membrane; continuously feeding into close proximity and in face-to-face relationship with the first strip a second strip formed of impermeable backing material; passing the first and second strips together through a filling and sealing station in which the material containing an active substance is introduced between the strips and pouches are formed by first sealing devices which seal the strips together in a longitudinal direction of the strips and second sealing devices which seal the strips together in a transverse direction of the strips; the size of the pouches being adjusted by adjusting the number position and/or frequency of operation of the first sealing devices and/or by adjusting the number position and/or frequency of operation of the second sealing devices.