Patents by Inventor Mark Rutz

Mark Rutz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Toll-Like Receptor 3 Antagonists
    Publication number: 20100166778
    Abstract: Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
    Type: Application
    Filed: October 30, 2009
    Publication date: July 1, 2010
    Inventors: Mark Cunningham, Yiqing Feng, Katharine Heeringa, Jinquan Luo, Robert Rauchenberger, Mark Rutz, Lani San Mateo, Robert Sarisky, Raymond Sweet, Fang Teng, Alexey Teplyakov, Sheng-Jiun Wu
  • Cell-free methods for identifying compounds that affect toll-like receptor 9 (TLR9) signaling
    Publication number: 20050100983
    Abstract: The invention is directed to methods for screening for a compound that affects interaction between a Toll-like receptor (TLR) and a ligand for the TLR. The methods involve direct measurement of interaction using, for example, surface plasmon resonance (SPR), particularly under conditions of pH that mimic those of the TLR in vivo. Compounds identified using the methods of the invention may be useful in the development of agents useful in the treatment of conditions characterized by undesirable immune activation, e.g., autoimmunity, inflammation, allergy, asthma, and transplantation.
    Type: Application
    Filed: November 5, 2004
    Publication date: May 12, 2005
    Applicants: Coley Pharmaceutical GmbH, Coley Pharmaceutical Group, Inc., Technische Universitat Munchen
    Inventors: Stefan Bauer, Grayson Lipford, Hermann Wagner, Mark Rutz