Patents by Inventor Mark S. Dennis

Mark S. Dennis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-TRANSFERRIN RECEPTOR / ANTI-BACE1 MULTISPECIFIC ANTIBODIES AND METHODS OF USE
    Publication number: 20180057604
    Abstract: The present invention relates to bispecific antibodies that bind to transferrin receptor and BACE1 and methods of using the same.
    Type: Application
    Filed: November 18, 2015
    Publication date: March 1, 2018
    Applicants: Genentech, Inc., Adimab LLC
    Inventors: Yichin Liu, Jasvinder Atwal, Cecilia Pui Chi Chiu, Ryan J. Watts, Yan WU, Eric Krauland, Michael Feldhaus, Yin Zhang, Joy Yu Zuchero, Jessica Couch, Mark S Dennis, James A Ernst, Gregory A Lazar
  • MASKED ANTI-CD3 ANTIBODIES AND METHODS OF USE
    Publication number: 20180057593
    Abstract: The invention provides masked anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
    Type: Application
    Filed: October 19, 2017
    Publication date: March 1, 2018
    Inventor: Mark S. DENNIS
  • ANTI-TRANSFERRIN RECEPTOR ANTIBODIES AND METHODS OF USE
    Publication number: 20180002433
    Abstract: The present invention relates to anti-transferrin receptor antibodies and methods of their use.
    Type: Application
    Filed: June 5, 2017
    Publication date: January 4, 2018
    Applicant: Genentech, Inc.
    Inventors: Yin Zhang, Joy Yu Zuchero, Jasvinder Atwal, Jessica Couch, Mark S. Dennis, James A. Ernst, Ryan J. Watts, Gregory A. Lazar
  • BLOOD BRAIN BARRIER RECEPTOR ANTIBODIES AND METHODS OF USE
    Publication number: 20180000964
    Abstract: The present invention relates to antibodies that bind to receptors expressed on the blood brain barrier and methods of using the same.
    Type: Application
    Filed: June 9, 2017
    Publication date: January 4, 2018
    Applicant: Genentech, Inc.
    Inventors: Christine Tan, Ryan J. Watts, Joy Yu Zuchero, Xiaocheng Chen, Mark S. Dennis
  • ANTIBODIES AND IMMUNOCONJUGATES AND USES THEREFOR
    Publication number: 20170234883
    Abstract: Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP-1 antibodies and immunoconjugates thereof are provided.
    Type: Application
    Filed: January 25, 2017
    Publication date: August 17, 2017
    Applicant: Genentech, Inc.
    Inventors: Mark S. DENNIS, Bonnee RUBINFELD, Paul POLAKIS, Aya JAKOBOVITS
  • ANTI-CD3 ANTIBODIES AND METHODS OF USE
    Publication number: 20170204194
    Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
    Type: Application
    Filed: March 29, 2017
    Publication date: July 20, 2017
    Inventors: Xiaocheng CHEN, Mark S. DENNIS, Allen J. EBENS, Jr., Teemu T. JUNTTILA, Robert F. KELLEY, Mary A. MATHIEU
  • Anti-transferrin receptor antibodies and methods of use
    Patent number: 9708406
    Abstract: The present invention relates to anti-transferrin receptor antibodies and methods of their use.
    Type: Grant
    Filed: May 20, 2014
    Date of Patent: July 18, 2017
    Assignee: GENENTECH, INC.
    Inventors: Yin Zhang, Joy Yu Zuchero, Jasvinder Atwal, Jessica Couch, Mark S. Dennis, James A. Ernst, Ryan J. Watts, Gregory A. Lazar
  • Antibodies and immunoconjugates and uses therefor
    Patent number: 9593167
    Abstract: Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP-1 antibodies and immunoconjugates thereof are provided.
    Type: Grant
    Filed: October 17, 2014
    Date of Patent: March 14, 2017
    Assignee: GENENTECH, INC.
    Inventors: Mark S. Dennis, Bonnee Rubinfeld, Paul Polakis, Aya Jakobovits
  • HUMANIZED ANTI-BETA7 ANTAGONISTS AND USES THEREFOR
    Publication number: 20170044261
    Abstract: The invention provides therapeutic anti-beta7 antibodies, compositions comprising, and methods of using these antibodies.
    Type: Application
    Filed: March 24, 2016
    Publication date: February 16, 2017
    Applicant: Genentech, Inc.
    Inventors: Sherman Fong, Mark S. Dennis
  • METHODS OF TREATING HER2-POSITIVE CANCERS USING PD-1 AXIS BINDING ANTAGONISTS AND ANTI-HER2 ANTIBODIES
    Publication number: 20170008971
    Abstract: The invention provides compositions and methods for treating HER2-postitive cancers. The method comprising administering a PD-1 axis binding antagonist and an antibody that targets HER2.
    Type: Application
    Filed: June 16, 2016
    Publication date: January 12, 2017
    Applicant: Genentech, Inc.
    Inventors: Mark S. DENNIS, Allen EBENS, Bryan IRVING, Teemu T. JUNTTILA, Ji LI
  • ANTI-CLL-1 ANTIBODIES AND METHODS OF USE
    Publication number: 20160368994
    Abstract: The present invention relates to anti-CLL-1 antibodies including anti-CLL-1 antibodies comprising a CLL-1 binding domain and a CD3 binding domain (e.g., anti-CLL-1/CD3 T cell dependent bispecific (TDB) antibody) and methods of using the same.
    Type: Application
    Filed: June 14, 2016
    Publication date: December 22, 2016
    Applicant: Genentech, Inc.
    Inventors: Robert F. Kelley, Steven R. Leong, Wei-Ching Liang, Mary Mathieu, Andrew G. Polson, Bing Zheng, Xiaocheng Chen, Cecilia Pui Chi Chiu, Mark S. Dennis, Allen Ebens, Yan Wu
  • ANTI-IL-4 ANTIBODIES AND BISPECIFIC ANTIBODIES AND USES THEREOF
    Publication number: 20160207995
    Abstract: The invention provides anti-IL-4 antibodies and bispecific antibodies and methods of using the same.
    Type: Application
    Filed: September 18, 2015
    Publication date: July 21, 2016
    Applicant: GENENTECH, INC.
    Inventors: Daniel G. Yansura, Nancy Y. Chiang, Mark S. Dennis, Michael Dillon, Germaine G. Fuh, Gerald R. Nakamura, Christoph Spiess, Lawren C. Wu, Yin Zhang
  • SERUM ALBUMIN BINDING PEPTIDES FOR TUMOR TARGETING
    Publication number: 20160185874
    Abstract: Peptide ligands having affinity for serum albumin are useful for tumor targeting. Conjugate molecules comprising a serum albumin binding peptide fused to a biologically active molecule demonstrate modified pharmacokinetic properties as compared with the biologically active molecule alone, including tissue (e.g., tumor) uptake, infiltration, and diffusion.
    Type: Application
    Filed: August 12, 2015
    Publication date: June 30, 2016
    Inventor: Mark S. Dennis
  • ANTI-CD79b ANTIBODIES AND METHODS OF USE
    Publication number: 20160159906
    Abstract: The invention provides anti-CD79b antibodies and methods of using the same.
    Type: Application
    Filed: December 4, 2015
    Publication date: June 9, 2016
    Applicant: Genentech, Inc.
    Inventors: Liping L. Sun, Yvonne Man-Yee Chen, Mark S. Dennis, Allen J. Ebens, JR., Andrew Polson
  • HUMANIZED ANTI-BETA7 ANTAGONISTS AND USES THEREFOR
    Publication number: 20150197560
    Abstract: The invention provides therapeutic anti-beta7 antibodies, compositions comprising, and methods of using these antibodies.
    Type: Application
    Filed: August 8, 2014
    Publication date: July 16, 2015
    Applicant: GENENTECH, INC.
    Inventors: Sherman Fong, Mark S. Dennis
  • ANTIBODIES AND IMMUNOCONJUGATES AND USES THEREFOR
    Publication number: 20150166674
    Abstract: Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP-1 antibodies and immunoconjugates thereof are provided.
    Type: Application
    Filed: October 17, 2014
    Publication date: June 18, 2015
    Inventors: Mark S. DENNIS, Bonnee RUBINFELD, Paul POLAKIS, Aya JAKOBOVITS
  • ANTI-CD3 ANTIBODIES AND METHODS OF USE
    Publication number: 20150166661
    Abstract: The invention provides anti-cluster of differentiation 3 (CD3) antibodies and methods of using the same.
    Type: Application
    Filed: December 17, 2014
    Publication date: June 18, 2015
    Applicant: GENENTECH, INC.
    Inventors: Xiaocheng CHEN, Mark S. DENNIS, Allen J. EBENS, JR., Teemu T. JUNTTILA, Robert F. KELLEY, Mary A. MATHIEU, Liping L. SUN
  • ANTI-TRANSFERRIN RECEPTOR ANTIBODIES AND METHODS OF USE
    Publication number: 20150110791
    Abstract: The present invention relates to anti-transferrin receptor antibodies and methods of their use.
    Type: Application
    Filed: May 20, 2014
    Publication date: April 23, 2015
    Applicant: GENENTECH, INC.
    Inventors: Yin Zhang, Joy Yu Zuchero, Jasvinder Atwal, Jessica Couch, Mark S. Dennis, James A. Ernst, Ryan J. Watts, Gregory A. Lazar
  • Antibodies and immunoconjugates and uses therefor
    Patent number: 8889847
    Abstract: Anti-STEAP-1 antibodies and immunoconjugates thereof are provided. Methods of using anti-STEAP-1 antibodies and immunoconjugates thereof are provided.
    Type: Grant
    Filed: February 13, 2013
    Date of Patent: November 18, 2014
    Assignee: Genentech, Inc.
    Inventors: Mark S. Dennis, Bonnee Rubinfeld, Paul Polakis, Aya Jakobovits
  • SERUM ALBUMIN BINDING PEPTIDES FOR TUMOR TARGETING
    Publication number: 20140294863
    Abstract: Peptide ligands having affinity for serum albumin are useful for tumor targeting. Conjugate molecules comprising a serum albumin binding peptide fused to a biologically active molecule demonstrate modified pharmacokinetic properties as compared with the biologically active molecule alone, including tissue (e.g., tumor) uptake, infiltration, and diffusion.
    Type: Application
    Filed: October 25, 2013
    Publication date: October 2, 2014
    Applicant: GENENTECH, INC.
    Inventor: Mark S. Dennis