Patents by Inventor Mark Samuel Briggs

Mark Samuel Briggs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for measuring binding of a test compound to a G-protein coupled receptor
    Patent number: 7674584
    Abstract: The invention provides a method for measuring binding of a test compound to a G-Protein Coupled Receptor (GPCR). The invention also provides a method for identifying and measuring the effect that an agent has upon modulating the binding of a test compound to a G-Protein Coupled Receptor.
    Type: Grant
    Filed: September 27, 2005
    Date of Patent: March 9, 2010
    Assignee: GE Healthcare UK Limited
    Inventors: Mark Samuel Briggs, Albert Francis Santos
  • Fluorescent nucleotide analogues
    Patent number: 7445902
    Abstract: The present invention provides fluorescent cyanine dye-based nucleotide analogues, in which the cyanine dye is coupled to the ?-phosphate group of a nucleoside triphosphate. Preferred embodiments of the invention are directed to fluorescent cyanine dye-based GTP analogues which may be employed in an homogeneous FRET-based assay to measure the binding of guanine nucleotides to GPCR polypeptides, or alternatively, to measure the effect of an exogenous ligand on GPCR protein binding.
    Type: Grant
    Filed: September 27, 2005
    Date of Patent: November 4, 2008
    Assignee: GE Healthcare UK Limited
    Inventors: Mark Samuel Briggs, John Anthony Smith, Albert Francis Santos