Patents by Inventor Mark Sandison

Mark Sandison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6897036
    Abstract: Methods of producing fluorescence from fluorogenic substrates reactive with a peroxidase enzyme are disclosed. Use of the methods in assays for peroxidase enzymes, peroxidase-labeled analytes are provided. Fluorogenic compounds, compositions and kits for reaction with peroxidase enzymes are described. Two modes of producing fluorescent compounds are described.
    Type: Grant
    Filed: June 6, 2002
    Date of Patent: May 24, 2005
    Assignee: Lumigen, Inc.
    Inventors: Hashem Akhavan-Tafti, Renuka de Silva, Mark Sandison, Richard Handley
  • Publication number: 20050106577
    Abstract: Solid phase materials for binding nucleic acids and methods of their use are disclosed. The materials feature a cleavable linker portion which can be cleaved to release bound nucleic acids. The solid phase materials comprise a solid support portion comprising a matrix selected from silica, glass, insoluble synthetic polymers, and insoluble polysaccharides to which is attached a nucleic acid binding portion for attracting and binding nucleic acids, the nucleic acid binding portion (NAB) being linked by a cleavable linker portion to the solid support portion. Preferred nucleic acid binding portions comprise a ternary or quaternary onium group. The materials can be in the form of microparticles, fibers, beads, membranes, test tubes or microwells and can further comprise a magnetic core portion. Methods of binding nucleic acids using the cleavable solid supports are disclosed as are their use in methods of isolating or purifying nucleic acids.
    Type: Application
    Filed: November 17, 2003
    Publication date: May 19, 2005
    Inventors: Hashem Akhavan-Tafti, Renuka Silva, Robert Eickholt, C. Gundlach, Richard Handley, Kenneth Lauwers, Mark Sandison, Wenhua Xie
  • Publication number: 20030232405
    Abstract: Methods of producing fluorescence from fluorogenic substrates reactive with a peroxidase enzyme are disclosed. Use of the methods in assays for peroxidase enzymes, peroxidase-labeled analytes are provided. Fluorogenic compounds, compositions and kits for reaction with peroxidase enzymes are described. Two modes of producing fluorescent compounds are described.
    Type: Application
    Filed: June 6, 2002
    Publication date: December 18, 2003
    Inventors: Hashem Akhavan-Tafti, Renuka de Silva, Mark Sandison, Richard Handley
  • Patent number: 5847130
    Abstract: Aqueous solutions of N-methylmorpholine N-oxide having reduced nitrosamine concentrations are produced by adding catalytic amounts of inorganic carbonate or bicarbonate or carboxylic acid or carboxylate salt.
    Type: Grant
    Filed: August 4, 1997
    Date of Patent: December 8, 1998
    Assignee: BASF Corporation
    Inventor: Mark Sandison
  • Patent number: 5693796
    Abstract: Aqueous solutions of N-methylmorpholine N-oxide having reduced nitrosamine concentrations are produced by adding catalytic amounts of inorganic carbonate or bicarbonate or carboxylic acid or carboxylate salt.
    Type: Grant
    Filed: August 14, 1996
    Date of Patent: December 2, 1997
    Assignee: BASF Corporation
    Inventor: Mark Sandison
  • Patent number: 5446197
    Abstract: A method of purifying acifluorfen to achieve a purity of greater than about 85% by weight involves heating to dissolution a solution of an acifluorfen crude wet cake and at least one solvent from the group of 1,2-dichlorobenzene, monochlorobenzene, o-xylene and p-xylene, with the solution having from about 10 to about 30 weight percent of acifluorfen crude wet cake. The-solution is then cooled until crystals of purified acifluorfen form. The crystals are then filtered at a temperature within the range of from about 0.degree. to about 30.degree. C. The filtered crystals are then recovered.
    Type: Grant
    Filed: June 17, 1993
    Date of Patent: August 29, 1995
    Assignee: BASF Corporation
    Inventors: Mark Sandison, Ron Eva, Lawrence E. James