Abstract: A negative pressure injection device which includes a suction cup and an inner skirt that encircles an injection port and depends into the interior of the suction cup. An injection member is surrounded by and protrudes below the inner skirt. When air is drawn from the suction cup an epidermis of a patient is drawn into the suction cup until the epidermis comes into contact with the inner skirt and that portion of the injection member protruding below the inner skirt. The inner skirt provides consistent epidermis positioning. The depth of injection is consistently defined by the extent to which the injection member protrudes below the inner skirt.

Abstract: Sampling systems that include an absorbent material a preservative, such as an analyte preservative, as well as related materials and methods, are disclosed.

Abstract: Sampling systems that include an absorbent material a preservative, such as an analyte preservative, as well as related materials and methods, are disclosed.

Abstract: Methods and systems for a catheter access port cleaning, disinfection or sterilization device are disclosed. The catheter access port cleaning, disinfection or sterilization device may comprise, a first housing having a power source and control circuit; a second housing shaped to mate with a catheter and having a first ultra-violet light source mounted therein, the first housing wired to the second housing to power the light source. When activated, the ultra-violet light source emits ultra-violet radiation that is transmitted from the second housing to the catheter attached to a patient. In this way, the device provides an efficient system for cleaning, disinfecting or sterilizing an access port in the second housing while reducing patient infections.

Abstract: A wearable thorax percussion device for dislodging mucous buildup in the airways of a human patient, the device comprising frame elements and electromechanical actuators retained by the frame elements to intermittently percuss the thorax, and an electronic controller and power source for generating and modulating an electrical signal to energize the actuator. The frame elements may be interconnected by a garment, or fasteners and elastic or adjustable strapping.

Abstract: A wearable thorax percussion device for dislodging mucous buildup in the airways of a human patient, the device comprising frame elements and electromechanical actuators retained by the frame elements to intermittently percuss the thorax, and an electronic controller and power source for generating and modulating an electrical signal to energize the actuator. The frame elements may be interconnected by a garment, or fasteners and elastic or adjustable strapping.

Abstract: The present invention teaches apparatuses, systems and methods for performing a variety of medical procedures, including those involving introducing one or more substances into a subjects body.

Abstract: Methods and systems are provided for sterilization. In one example, a device may include a body with a flexible tether and a receiving aperture having a central axis, the body forming an internal cavity, the cavity housing at least one circular battery with a central axis perpendicular to the central axis of the aperture; and a UV source positioned at an end of the receiving aperture. Various other additional features and alternative configurations are included.

Abstract: A negative pressure injection device which includes a suction cup and an inner skirt that encircles an injection port and depends into the interior of the suction cup. An injection member is surrounded by and protrudes below the inner skirt. When air is drawn from the suction cup an epidermis of a patient is drawn into the suction cup until the epidermis comes into contact with the inner skirt and that portion of the injection member protruding below the inner skirt. The inner skirt provides consistent epidermis positioning. The depth of injection is consistently defined by the extent to which the injection member protrudes below the inner skirt.

Abstract: The present invention teaches apparatuses, systems and methods for performing a variety of medical procedures, including those involving introducing one or more substances into a subject's body. In some embodiments, the invention teaches automatically performing guided injections into a tissue site (e.g. spinal cord) of a subject by using one or more electronically operated components including a cannula, a syringe pump, and a stereotactic device.

Abstract: The present disclosure relates to gastrointestinal (GI) tract detection methods, devices and systems.

Abstract: Ingestible devices capable of delivering a dispensable substance, such as, for example, a therapeutic agent, as well as related components, systems and methods, are disclosed. A removably attachable storage reservoir configured to be used with an ingestible device and capable of storing dispensable substance, such as, for example, a therapeutic agent, as well as related components, systems and methods, are also disclosed.

Abstract: Ingestible devices configured to obtain samples when present in the GI tract of a subject, as well as related systems and methods, are disclosed. Sampling systems that include an absorbent material a preservative, such as an analyte preservative, as well as related materials and methods, are also disclosed.

Abstract: Sampling systems that include an absorbent material a preservative, such as an analyte preservative, as well as related materials and methods, are disclosed.

Abstract: Modules, devices, systems and methods for measuring or detecting cysteine and/or methionine metabolite levels in a sample from a subject are disclosed. Various embodiments of the present invention concern modules, devices, systems and methods for prognosing or diagnosing cancer, for example, prostate, colon, ovarian or breast cancer; predicting the risk or probability of cancer recurrence; and/or for predicting, detecting and/or monitoring cystinuria or cystine stone disease.

Abstract: Various embodiments are described herein for a device, system, and method for identifying a location of an ingestible device within a gastrointestinal tract of a body. In some embodiments, the ingestible device includes a sensing unit with an axial optical sensing sub-unit located proximal to at least one end of the device, and a radial optical sensing sub-unit located proximal to a radial wall of the device, and may autonomously identify a location within the gastrointestinal tract. In some embodiments, the ingestible device includes optical illumination sources and detectors that operate at a plurality of different wavelengths, and may discern regions of a gastrointestinal tract by using the reflection properties of organ tissue and occasional particulates. In some embodiments, the ingestible device may sample fluid or release medicament based on a detected device location.

Abstract: A wearable thorax percussion device for dislodging mucous buildup in the airways of a human patient, the device comprising a garment fitting over the thorax, a rigid element attached to the external surface of the garment, an electromechanical actuator retained by the rigid element to intermittently percuss the thorax, and an electronic controller for generating and modulating an electrical signal to energize the actuator. The rigid element may be adjustably positioned on the garment to accommodate thoraxes of different dimensions. The actuator may be compressible between the rigid element and the thorax to better maintain contact with the thorax.

Abstract: Methods and systems are provided for sterilization. In one example, a device may include a body with a flexible tether and a receiving aperture having a central axis, the body forming an internal cavity, the cavity housing at least one circular battery with a central axis perpendicular to the central axis of the aperture; and a UV source positioned at an end of the receiving aperture. Various other additional features and alternative configurations are included.

Abstract: A wearable thorax percussion device for dislodging mucous buildup in the airways of a human patient, the device comprising frame elements and electromechanical actuators retained by the frame elements to intermittently percuss the thorax, and an electronic controller and power source for generating and modulating an electrical signal to energize the actuator. The frame elements may be interconnected by a garment, or fasteners and elastic or adjustable strapping.

Abstract: A wearable thorax percussion device for dislodging mucous buildup in the airways of a human patient, the device comprising frame elements and electromechanical actuators retained by the frame elements to intermittently percuss the thorax, and an electronic controller and power source for generating and modulating an electrical signal to energize the actuator. The frame elements may be interconnected by a garment, or fasteners and elastic or adjustable strapping.