Patents by Inventor Mark Shults
Mark Shults has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20100081910Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.Type: ApplicationFiled: December 3, 2009Publication date: April 1, 2010Applicant: DexCom, Inc.Inventors: Mark Brister, Mark Shults, Sean Saint, James R. Petisce, David K. Wong, Kum Ming Woo
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Publication number: 20100076283Abstract: Systems and methods of use involving sensors having a particle-containing domain are provided for continuous analyte measurement in a host. In some embodiments, a continuous analyte measurement system is configured to be wholly, transcutaneously, intravascularly or extracorporeally implanted.Type: ApplicationFiled: September 17, 2009Publication date: March 25, 2010Applicant: DexCom, Inc.Inventors: Peter C. Simpson, Robert J. Boock, Matthew Wightlin, Mark Shults
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Publication number: 20100041971Abstract: An implantable analyte sensor including a sensing region for measuring the analyte and a non-sensing region for immobilizing the sensor body in the host. The sensor is implanted in a precisely dimensioned pocket to stabilize the analyte sensor in vivo and enable measurement of the concentration of the analyte in the host before and after formation of a foreign body capsule around the sensor. The sensor further provides a transmitter for RF transmission through the sensor body, electronic circuitry, and a power source optimized for long-term use in the miniaturized sensor body.Type: ApplicationFiled: October 29, 2009Publication date: February 18, 2010Applicant: DexCom, Inc.Inventors: Paul V. Goode, JR., Arnold L. Holmquist, Mark A. Tapsak, Mark Shults, Victoria Carr-Brendel, James H. Brauker, Paul V. Neale, Jason D. McClure, Mark Brister, Peter C. Simpson, Rathbun K. Rhodes
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Patent number: 7657297Abstract: An implantable analyte sensor including a sensing region for measuring the analyte and a non-sensing region for immobilizing the sensor body in the host. The sensor is implanted in a precisely dimensioned pocket to stabilize the analyte sensor in vivo and enable measurement of the concentration of the analyte in the host before and after formation of a foreign body capsule around the sensor. The sensor further provides a transmitter for RF transmission through the sensor body, electronic circuitry, and a power source optimized for long-term use in the miniaturized sensor body.Type: GrantFiled: May 3, 2004Date of Patent: February 2, 2010Assignee: DexCom, Inc.Inventors: Peter C. Simpson, Mark Shults, Rathbun K. Rhodes, Paul V. Goode, Jr., Arnold L. Holmquist
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Publication number: 20090287074Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.Type: ApplicationFiled: August 4, 2009Publication date: November 19, 2009Applicant: DexCom, Inc.Inventors: Mark Shults, Apurv U. Kamath, Mark Brister, David K. Wong
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Patent number: 7615007Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.Type: GrantFiled: March 26, 2007Date of Patent: November 10, 2009Assignee: DexCom, Inc.Inventors: Mark Shults, Apurv U. Kamath, Mark Brister, David K. Wong
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Publication number: 20090062633Abstract: An implantable analyte sensor including a sensing region for measuring the analyte and a non-sensing region for immobilizing the sensor body in the host. The sensor is implanted in a precisely dimensioned pocket to stabilize the analyte sensor in vivo and enable measurement of the concentration of the analyte in the host before and after formation of a foreign body capsule around the sensor. The sensor further provides a transmitter for RF transmission through the sensor body, electronic circuitry, and a power source optimized for long-term use in the miniaturized sensor body.Type: ApplicationFiled: November 4, 2008Publication date: March 5, 2009Applicant: DexCorn, Inc.Inventors: James H. Brauker, Mark A. Tapsak, Mark Shults, Victoria Carr-Brendel, Jack C. Fisher, William J. Seare, JR., Paul V. Neale
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Publication number: 20090030294Abstract: An implantable analyte sensor including a sensing region for measuring the analyte and a non-sensing region for immobilizing the sensor body in the host. The sensor is implanted in a precisely dimensioned pocket to stabilize the analyte sensor in vivo and enable measurement of the concentration of the analyte in the host before and after formation of a foreign body capsule around the sensor. The sensor further provides a transmitter for RF transmission through the sensor body, electronic circuitry, and a power source optimized for long-term use in the miniaturized sensor body.Type: ApplicationFiled: October 7, 2008Publication date: January 29, 2009Applicant: DexCom, Inc.Inventors: James R. Petisce, Mark Brister, Mark Shults, James H. Brauker, Paul V. Neale
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Publication number: 20080086273Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.Type: ApplicationFiled: March 26, 2007Publication date: April 10, 2008Applicant: DexCom, Inc.Inventors: Mark Shults, Apurv U. Kamath, Mark Brister, David K. Wong
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Publication number: 20080086044Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.Type: ApplicationFiled: March 26, 2007Publication date: April 10, 2008Applicant: DexCom, Inc.Inventors: Mark Brister, Mark Shults, Sean Saint, James R. Petisce, David K. Wong, Kum Ming Woo
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Publication number: 20080086042Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.Type: ApplicationFiled: March 26, 2007Publication date: April 10, 2008Applicant: DexCom, Inc.Inventors: Mark Brister, Sean Saint, James R. Petisce, Mark Shults, Jacob S. Leach, David K. Wong, Kum Ming Woo
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Publication number: 20070032718Abstract: Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices include unique architectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.Type: ApplicationFiled: October 10, 2006Publication date: February 8, 2007Inventors: Mark Shults, Stuart Updike, Rathbun Rhodes, Barbara Gilligan, Mark Tapsak
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Publication number: 20060258761Abstract: Membrane systems incorporating silicone polymers are described for use in implantable analyte sensors. Some layers of the membrane system may comprise a blend of a silicone polymer with a hydrophilic polymer, for example, a triblock poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) polymer. Such polymeric blends provide for both high oxygen solubility and aqueous analyte solubility.Type: ApplicationFiled: April 14, 2006Publication date: November 16, 2006Inventors: Robert Boock, Monica Rixman, Mark Tapsak, Mark Shults, Rathbun Rhodes
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Publication number: 20060204536Abstract: A biointerface membrane for an implantable device including a nonresorbable solid portion with a plurality of interconnected cavities therein adapted to support tissue ingrowth in vivo, and a bioactive agent incorporated into the biointerface membrane and adapted to modify the tissue response is provided. The bioactive agents can be chosen to induce vascularization and/or prevent barrier cell layer formation in vivo, and are advantageous when used with implantable devices wherein solutes are transported across the device-tissue interface.Type: ApplicationFiled: May 3, 2006Publication date: September 14, 2006Inventors: Mark Shults, James Brauker, Victoria Carr-Brendel, Mark Tapsak, Dubravka Markovic
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Publication number: 20060198864Abstract: A biointerface membrane for an implantable device including a nonresorbable solid portion with a plurality of interconnected cavities therein adapted to support tissue ingrowth in vivo, and a bioactive agent incorporated into the biointerface membrane and adapted to modify the tissue response is provided. The bioactive agents can be chosen to induce vascularization and/or prevent barrier cell layer formation in vivo, and are advantageous when used with implantable devices wherein solutes are transported across the device-tissue interface.Type: ApplicationFiled: May 3, 2006Publication date: September 7, 2006Inventors: Mark Shults, James Brauker, Victoria Carr-Brendel, Mark Tapsak, Dubravka Markovic
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Publication number: 20060195029Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous and subcutaneous measurement of glucose in a host.Type: ApplicationFiled: January 17, 2006Publication date: August 31, 2006Inventors: Mark Shults, Rathburn Rhodes, Stuart Updike, James Brauker
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Publication number: 20060086624Abstract: The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.Type: ApplicationFiled: November 16, 2005Publication date: April 27, 2006Inventors: Mark Tapsak, Rathbun Rhodes, Mark Shults, Jason McClure
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Publication number: 20060068208Abstract: The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.Type: ApplicationFiled: November 16, 2005Publication date: March 30, 2006Inventors: Mark Tapsak, Rathbun Rhodes, Mark Shults, Jason McClure
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Publication number: 20050242479Abstract: Abstract of the Disclosure An implantable analyte sensor including a sensing region for measuring the analyte and a non-sensing region for immobilizing the sensor body in the host. The sensor is implanted in a precisely dimensioned pocket to stabilize the analyte sensor in vivo and enable measurement of the concentration of the analyte in the host before and after formation of a foreign body capsule around the sensor. The sensor further provides a transmitter for RF transmission through the sensor body, electronic circuitry, and a power source optimized for long-term use in the miniaturized sensor body.Type: ApplicationFiled: May 3, 2004Publication date: November 3, 2005Inventors: James Petisce, Mark Brister, Mark Shults, James Brauker, Paul Neale
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Publication number: 20050245799Abstract: Abstract of the Disclosure An implantable analyte sensor including a sensing region for measuring the analyte and a non-sensing region for immobilizing the sensor body in the host. The sensor is implanted in a precisely dimensioned pocket to stabilize the analyte sensor in vivo and enable measurement of the concentration of the analyte in the host before and after formation of a foreign body capsule around the sensor. The sensor further provides a transmitter for RF transmission through the sensor body, electronic circuitry, and a power source optimized for long-term use in the miniaturized sensor body.Type: ApplicationFiled: May 3, 2004Publication date: November 3, 2005Applicant: DexCom, Inc.Inventors: James Brauker, Mark Tapsak, Mark Shults, Victoria Carr-Brendel, Jack Fisher, William Seare, Paul Neale