Patents by Inventor Mark Sleevi

Mark Sleevi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Purified rhlGF-I/rhlGFBP-3 complexes and their method of manufacture
    Publication number: 20060166884
    Abstract: Complexes of IGF-I and IGFBP-3 with new levels of purity are provided. Chromatographic techniques have been developed that remove contaminants, such as mass and charge variants of IGFBP-3. The new techniques enable the production of high-quality pharmaceutical compositions comprising IGF-I/IGFBP-3 complexes.
    Type: Application
    Filed: December 20, 2005
    Publication date: July 27, 2006
    Inventors: Mark Sleevi, Glen Kelley
  • Compositions comprising D-chiro inositol and sulfonylureas and methods of treatment thereof
    Patent number: 6492339
    Abstract: The present invention provides compositions comprising synergistically effective amounts of D-chiro-inositol and sulfonylureas. The present invention also provides methods to treat a subject with insulin resistance comprising administration of D-chiro-inositol and sulfonylurea, either as concurrent single agents or as a combined composition. In particular the methods of the present invention are useful in maintaining pancreatic beta cell function/viability and thus delay diabetes progression. The methods and compositions of the present invention are particularly efficacious in treating insulin resistant subjects with a fasting blood glucose level of less than or equal to 180 mg/dL.
    Type: Grant
    Filed: October 26, 2001
    Date of Patent: December 10, 2002
    Assignee: Insmed, Incorporated
    Inventors: Mark Sleevi, Geoffrey Allan