Patents by Inventor Mark Stephen Baird

Mark Stephen Baird has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190250160
    Abstract: A method of determining whether an individual is infected with a mycobacterial disease, the method comprising: (a) providing a system which comprises an antigen; (b) contacting the system with a sample obtained from the individual; and (c) detecting the presence or absence of binding of a biomarker in the sample with the antigen; wherein the antigen is a mycolic acid wax ester derived antigen.
    Type: Application
    Filed: August 12, 2016
    Publication date: August 15, 2019
    Inventors: Mark Stephen Baird, Christopher David Gwenin, Juma'a Raheem Najeem Al Dulayymi, Salam Ghafour Taher
  • Publication number: 20180231547
    Abstract: A method of determining whether an individual is infected with a mycobacterial disease, the method comprising: (a) providing a system which comprises an antigen; (b) contacting the system with a sample obtained from the individual; and (c) detecting the presence or absence of binding of a biomarker in the sample with the antigen; wherein the antigen is an arabinose ester of a mycolic acid or an analogue thereof.
    Type: Application
    Filed: August 12, 2016
    Publication date: August 16, 2018
    Inventors: Mark Stephen Baird, Christopher David Gwenin, Juma'a Raheem Najeem Al-Dulayymi, Mohsin Omar Mohammed
  • Patent number: 9945852
    Abstract: A method of determining the presence or absence in a sample of a biomarker, the method comprising: (a) linking an antigen to colloidal gold to provide a gold-antigen species; (b) contacting the gold-antigen species with the sample; (c) adding a diagnosis agent to the sample; and (d) observing the color of the sample.
    Type: Grant
    Filed: May 4, 2012
    Date of Patent: April 17, 2018
    Assignee: Arcis Biotechnology Holdings Limited
    Inventors: Christopher David Gwenin, Mark Stephen Baird, Vanessa Valerie Gwenin, Mark Pitts
  • Publication number: 20170248595
    Abstract: A method of determining the presence or absence in a sample of a biomarker, the method comprising the steps of (a) providing a porous substrate which carries an antigen; (b) contacting the substrate with the sample; (c) contacting the substrate with a composition comprising a secondary antibody; and (d) observing the substrate. The method may enable a very quick, simple test to be carried out to determine whether or not a particular sample contains a biomarker, for example an antibody indicative of infection with a mycobacterial disease. A kit and a device for determining the presence or absence in a sample of a biomarker are also described.
    Type: Application
    Filed: August 13, 2015
    Publication date: August 31, 2017
    Inventors: Mark Stephen Baird, Christopher David Gwenin, Vanessa Valerie Gwenin, Joanne Louise Hacking, Mark Pitts
  • Publication number: 20170242005
    Abstract: A method of determining whether an individual is infected with mycobacteria. The method comprising the steps of (a) providing a system which comprises at least two different mycolic-acid derived antigens; (b) introducing a sample obtained from the individual into the system and into contact with each of the at least two different mycolic-acid derived antigens; and (c) detecting the presence or absence of the binding of a biomarker in the sample with each antigen in the system. The method may be particularly suitable for determining the presence or absence of a disease antibody indicative of infection with any disease caused by infection with mycobacteria, for example tuberculosis, leprosy, pulmonary disease, burili ulcer, Johne's disease and bovine tuberculosis. A kit and device are also described. The present invention may provide an over the counter device to allow individuals to check on a routine basis that they have normal immune responses.
    Type: Application
    Filed: August 13, 2015
    Publication date: August 24, 2017
    Inventors: Mark Stephen Baird, Christopher David Gwenin, Vanessa Valerie Gwenin, Alison Jones
  • Patent number: 9506921
    Abstract: A method of determining the presence or absence in a sample of a biomarker indicative of exposure to mycobacteria, the method comprising: (a) providing a substrate carrying a mycolic acid derived antigen; (b) contacting the substrate with the sample; (c) contacting the substrate with a fluorophore species; (d) creating an evanescent wave at the boundary of the substrate and the sample; (e) detecting the presence or absence of fluorescence.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: November 29, 2016
    Assignee: Bangor University
    Inventors: Christopher David Gwenin, Mark Stephen Baird
  • Patent number: 9447010
    Abstract: The present invention discloses a simple method for transforming cashew nut shell liquid into an active herbicidal composition.
    Type: Grant
    Filed: February 13, 2013
    Date of Patent: September 20, 2016
    Assignee: BANGOR UNIVERSITY
    Inventors: Viacheslav Vitalievich Tverezovskiy, Radek Messias Braganca, Frank Arthur Howard, Spencer Matthew Gould, Paul Anthony Fowler, Mark Stephen Baird
  • Patent number: 9206213
    Abstract: A method of preparing a compound of formula (III): (M)x-(S)y-(M?)z??(III) wherein x is from 1 to 6, y is from 1 to 12, z is from 0 to 10, each M and each M? is independently a mycolic acid residue including a ?-hydroxy acid moiety and each S is a monosaccharide unit; the method comprising reacting one or more mycolic acids with one or more saccharide units wherein the hydroxyl group of each ?-hydroxy acid moiety is protected prior to reaction with the one or more saccharide units.
    Type: Grant
    Filed: December 9, 2013
    Date of Patent: December 8, 2015
    Assignee: Bangor University
    Inventors: Mark Stephen Baird, Juma'a Raheem Najeem Al Dulayymi, Johan Adriaan Marc Grooten, Seppe Vander Beken, Maximilliano Maza-Inglesias
  • Publication number: 20150018569
    Abstract: The present invention discloses a simple method for transforming cashew nut shell liquid into an active herbicidal composition.
    Type: Application
    Filed: February 13, 2013
    Publication date: January 15, 2015
    Applicant: BANOR UNIVERSIITY
    Inventors: Viacheslav Vitalievich Tverezovskiy, Radek Messias Braganca, Frank Arthur Howard, Spencer Matthew Gould, Paul Anthony Fowler, Mark Stephen Baird
  • Patent number: 8889894
    Abstract: A compound of formula (I) for use in the treatment of a disease of the immune system; wherein R is an optionally-substituted alkyl, alkenyl, alkynyl, aryl, arylalkyl or alkylaryl moiety having from 1 to 50 carbon atoms; R1 is an optionally-substituted alkyl, alkenyl, alkynyl, aryl, arylalkyl or alkylaryl moiety having from 1 to 40 carbon atoms; each of R2, R3 and R4 is independently selected from an optionally-substituted alkylene, alkenylene, alkynylene, arylene, arylalkylene or alkylarylene moiety having from 1 to 40 carbon atoms; each of X, Y and Z is independently selected from an optionally-substituted alkylene, alkenylene, alkenylene, arylene, alkylarylene, cycloalkylene, ketone, ester, amide, imide, imine, thioether, ether, thioester and thioketone; and P is selected from hydrogen, an alkyl group, a sugar residue, or a metal, phosphonium or ammonium species; wherein at least one of X, Y and Z includes a moiety selected from cyclopropyl, C=A, C-AH and C—OR5; wherein R5 is alkyl or haloalkyl, and A is O,
    Type: Grant
    Filed: April 22, 2009
    Date of Patent: November 18, 2014
    Assignees: Bangor University, Universiteit Gent
    Inventors: Mark Stephen Baird, Juma′ a Raheem Najeem Al-Dulayy-mi, Cornelias Theunissen, Gani Koza, Seppe Vander-Beken, Johan Adriaan Marc Grooten
  • Publication number: 20140178434
    Abstract: A method of preparing a compound of formula (III): (M)x-(S)y-(M?)z??(III) wherein x is from 1 to 6, y is from 1 to 12, z is from 0 to 10, each M and each M? is independently a mycolic acid residue including a ?-hydroxy acid moiety and each S is a monosaccharide unit; the method comprising reacting one or more mycolic acids with one or more saccharide units wherein the hydroxyl group of each ?-hydroxy acid moiety is protected prior to reaction with the one or more saccharide units.
    Type: Application
    Filed: December 9, 2013
    Publication date: June 26, 2014
    Applicant: Bangor University
    Inventors: Mark Stephen Baird, Juma'a Raheem Najeem Al Dulayymi, Johan Adriaan Marc Grooten, Seppe Vander Beken, Maximilliano Maza-Inglesias
  • Patent number: 8728515
    Abstract: A compound of formula (I) for use as an adjuvant in vaccination; wherein R is an optionally-substituted alkyl, alkenyl, alkynyl, aryl, arylalkyl or alkylaryl moiety having from 1 to 50 carbon atoms; R1 is an optionally-substituted alkyl, alkenyl, alkynyl, aryl, arylalkyl or alkylaryl moiety having from 1 to 40 carbon atoms; each of R2, R3 and R4 is independently selected from an optionally-substituted alkylene, alkenylene, alkynylene, arylene, arylalkylene or alkylarylene moiety having from 1 to 40 carbon atoms; each of X, Y and Z is independently selected from an optionally-substituted alkylene, alkenylene, alkynylene, arylene, alkylarylene or cycloalkylene, ketone, ester, amide, imide, imine, thioether, ether, thioester, thioketone; and P is selected from hydrogen, an alkyl group, a sugar residue, or a metal, phosphonium or ammonium species; wherein at least one of X, Y and Z includes a moiety selected from cyclopropyl, C=A, C-AH and C—OR5; wherein R5 is alkyl or haloalkyl, and A is S, O or NR6, wherein R6
    Type: Grant
    Filed: April 22, 2009
    Date of Patent: May 20, 2014
    Assignees: Bangor University, Universiteit Gent
    Inventors: Mark Stephen Baird, Juma' a Raheem Najeem Al-Dulayymi, Cornelia Theunissen, Gani Koza, Seppe Vander Beken, Johan Adriaan Marc Grooten
  • Publication number: 20140127709
    Abstract: A method of determining the presence or absence in a sample of a biomarker, the method comprising: (a) linking an antigen to colloidal gold to provide a gold-antigen species; (b) contacting the gold-antigen species with the sample; (c) adding a diagnosis agent to the sample; and (d) observing the colour of the sample.
    Type: Application
    Filed: May 4, 2012
    Publication date: May 8, 2014
    Applicant: Bangor University
    Inventors: Christopher David Gwenin, Mark Stephen Baird, Vanessa Valerie Gwenin, Mark Pitts
  • Publication number: 20140051599
    Abstract: A method of determining the presence or absence in a sample of a biomarker indicative of exposure to mycobacteria, the method comprising: (a) providing a substrate carrying a mycolic acid derived antigen; (b) contacting the substrate with the sample; (c) contacting the substrate with a fluorophore species; (d) creating an evanescent wave at the boundary of the substrate and the sample; (e) detecting the presence or absence of fluorescence.
    Type: Application
    Filed: March 30, 2012
    Publication date: February 20, 2014
    Applicant: Bangor University
    Inventors: Christopher David Gwenin, Mark Stephen Baird
  • Patent number: 8530683
    Abstract: A method of obtaining a solid component rich in a petroselinic compound from the seed of a plant of the Apiaceae or Araliaceae families, the method comprising: (a) treating a portion of the seed of the plant with an extraction solvent; and (b) inducing formation of the solid component.
    Type: Grant
    Filed: December 22, 2008
    Date of Patent: September 10, 2013
    Assignee: Bangor University
    Inventors: Mark Stephen Baird, David Preskett
  • Publication number: 20120296073
    Abstract: A process of obtaining a saponin-rich component from a plant of the Araliaceae family, the process comprising the steps of: (a) treating a portion of the plant with an extraction solvent in which saponin-containing compounds are soluble; and (b) treating the portion of plant or the extract obtained therefrom to remove fatty acid residues from said portion of plant or extract thereof.
    Type: Application
    Filed: May 11, 2012
    Publication date: November 22, 2012
    Applicant: BANGOR UNIVERSITY
    Inventors: Mark Stephen Baird, David Preskett
  • Publication number: 20120045478
    Abstract: A method of preparing a compound of formula (III): wherein x is from 1 to 6, y is from 1 to 12, z is from 0 to 10, each M and each M? is independently a mycolic acid residue including a ?-hydroxy acid moiety and each S is a monosaccharide unit; the method comprising reacting one or more mycolic acids with one or more saccharide units wherein the hydroxyl group of each ?-hydroxy acid moiety is protected prior to reaction with the one or more saccharide units.
    Type: Application
    Filed: January 29, 2010
    Publication date: February 23, 2012
    Applicant: BANGOR UNIVERSITY
    Inventors: Mark Stephen Baird, Juma'a Raheem Najeem Al Dulayymi, Johan Adriaan Marc Grooten, Seppe Vander Beken, Maximilliano Maza-Inglesias
  • Publication number: 20110150981
    Abstract: A compound of formula (I) for use in the treatment of a disease of the immune system; wherein R is an optionally-substituted alkyl, alkenyl, alkynyl, aryl, arylalkyl or alkylaryl moiety having from 1 to 50 carbon atoms; R1 is an optionally-substituted alkyl, alkenyl, alkynyl, aryl, arylalkyl or alkylaryl moiety having from 1 to 40 carbon atoms; each of R2, Wand R4 is independently selected from an optionally-substituted alkylene, alkenylene, alkynylene, arylene, arylalkylene or alkylarylene moiety having from 1 to 40 carbon atoms; each of X, Y and Z is independently selected from an optionally-substituted alkylene, alkenylene, alkenylene, arylene, alkylarylene, cycloalkylene, ketone, ester, amide, imide, imine, thioether, ether, thioester and thioketone; and P is selected from hydrogen, an alkyl group, a sugar residue, or a metal, phosphonium or ammonium species; wherein at least one of X, Y and Z includes a moiety selected from cyclopropyl, C=A, C-AH and C-OR5; wherein R5 is alkyl or haloalkyl, and A is O, S
    Type: Application
    Filed: April 22, 2009
    Publication date: June 23, 2011
    Applicant: Bangor University
    Inventors: Mark Stephen Baird, Juma' a Raheem Najeem Al-Dulayymi, Cornelias Theunissen, Gani Koza, Seppe Vander Beken, Johan Adriann March Grooten
  • Publication number: 20110142916
    Abstract: A compound of formula (I) for use as an adjuvant in vaccination; wherein R is an optionally-substituted alkyl, alkenyl, alkynyl, aryl, arylalkyl or alkylaryl moiety having from 1 to 50 carbon atoms; R1 is an optionally-substituted alkyl, alkenyl, alkynyl, aryl, arylalkyl or alkylaryl moiety having from 1 to 40 carbon atoms; each of R2, R3 and R4 is independently selected from an optionally-substituted alkylene, alkenylene, alkynylene, arylene, arylalkylene or alkylarylene moiety having from 1 to 40 carbon atoms; each of X, Y and Z is independently selected from an optionally-substituted alkylene, alkenylene, alkynylene, arylene, alkylarylene or cycloalkylene, ketone, ester, amide, imide, imine, thioether, ether, thioester, thioketone; and P is selected from hydrogen, an alkyl group, a sugar residue, or a metal, phosphonium or ammonium species; wherein at least one of X, Y and Z includes a moiety selected from cyclopropyl, C=A, C-AH and C—OR5; wherein R5 is alkyl or haloalkyl, and A is S, O or NR6, wherein R6
    Type: Application
    Filed: April 22, 2009
    Publication date: June 16, 2011
    Applicants: BANGOR UNIVERSITY, GHENT UNIVERSITY
    Inventors: Mark Stephen Baird, Juma' a Raheem Najeem Al-Dulayymi, Cornelias Theunissen, Gani Koza, Seppe Vander Beken, Johan Adriann Marc Grooten
  • Publication number: 20110009487
    Abstract: A method of obtaining a solid component rich in a petroselinic compound from the seed of a plant of the Apiaceae or Araliaceae families, the method comprising: (a) treating a portion of the seed of the plant with an extraction solvent; and (b) inducing formation of the solid component.
    Type: Application
    Filed: December 22, 2008
    Publication date: January 13, 2011
    Applicant: BANGOR UNIVERSITY
    Inventors: Mark Stephen Baird, David Preskett