Patents by Inventor Mark Steven Howansky

Mark Steven Howansky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12233028
    Abstract: A valving arrangement is provided herein for regulating fluidics of modules usable in a combinatorial drug delivery device. The valving includes a slidable piston valve, adjustable to selectively seal an outlet path from a drug vial and a sealing port, in parallel to a vent, for selectively sealing an inlet path to the drug vial. Advantageously, the subject invention allows for applied negative pressure to adjust the valving to allow flow between serially-connected modules forming a drug delivery device.
    Type: Grant
    Filed: November 9, 2020
    Date of Patent: February 25, 2025
    Assignee: BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Martin John McLoughlin, Stephen Lawrence Zieminski, Mark Steven Howansky, Mariano Mumpower, Melanie Marie Springer, Katherine Alina Goetz, Benjamin Richard Lane
  • Publication number: 20240415736
    Abstract: A combinatorial drug delivery device is provided for delivering a predetermined selection of drug components, each of the drug components being contained in a drug vial. The device includes a plurality of modules, wherein each of the modules includes: a body having an interior volume formed to accommodate a drug vial; a cannula protruding into the interior volume, the cannula terminating at a free end, first and second openings being formed in the free end with first and second lumens extending therefrom and through the cannula; a socket located on an exterior portion of the body; a first passageway extending between, and in communication with, the socket and the first lumen; a boss protruding from an exterior portion of the body; and, a second passageway extending from, and in communication with the second lumen, the second passageway extending through the boss to terminate at an exit opening formed therein.
    Type: Application
    Filed: August 30, 2024
    Publication date: December 19, 2024
    Inventors: Martin John McLoughlin, Mark Steven Howansky, Steven Lawrence Zieminski, Chester Larrow, Mariano Mumpower
  • Publication number: 20240390580
    Abstract: In one aspect, a drug delivery device is provided herein including: a monolithic body having a plurality of fluid ducts and at least one outlet duct formed therein; a plurality of drug cartridges attached to the body, the drug cartridges each including a reservoir for accommodating at least one drug wherein, the plurality of fluid ducts is arranged to convey the drugs from the drug cartridges to the at least one outlet duct; and, a needle support spaced from the body, the needle support including a needle configured for insertion into a patient for drug delivery, the needle support including adhesive for releasable securement to a patient, wherein, the needle support is connected to the body by a flexible tether through which passes at least one fluid passageway formed to convey drug from the at least one outlet duct to the needle.
    Type: Application
    Filed: June 13, 2022
    Publication date: November 28, 2024
    Inventors: Martin John McLoughlin, Mark Steven Howansky, George Tyler Currier, Peter William Heyman, Yuhong Wu, Erinc Sahin, Shreya Shashank Kulkarni, Ankur Sagar Kulshrestha, Xiaodong Chen, Haresh Tukaram More, Krishna Jagdish Patel, John Christian Knutsen, James William Kidner Bradford, Simon Francis Brereton, Timothy Donald Barrow-Williams, Christopher William Rosier, Jeffrey Nicholas Philippson, Ryan Anthony McGinley, Francesco Giuseppe Sasia, Holly Charlotte Palmer, Tomas Alexander Ogg Correa, Carys Eleri Lee, Paul Antony Merritt, Terence Zhi Seow
  • Patent number: 12102595
    Abstract: A combinatorial drug delivery device is provided for delivering a predetermined selection of drug components, each of the drug components being contained in a drug vial. The device includes a plurality of modules, wherein each of the modules includes: a body having an interior volume formed to accommodate a drug vial; a cannula protruding into the interior volume, the cannula terminating at a free end, first and second openings being formed in the free end with first and second lumens extending therefrom and through the cannula; a socket located on an exterior portion of the body; a first passageway extending between, and in communication with, the socket and the first lumen; a boss protruding from an exterior portion of the body; and, a second passageway extending from, and in communication with the second lumen, the second passageway extending through the boss to terminate at an exit opening formed therein.
    Type: Grant
    Filed: May 10, 2019
    Date of Patent: October 1, 2024
    Assignee: BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Martin John McLoughlin, Mark Steven Howansky, Stephen Lawrence Zieminski, Chester Larrow, Mariano Mumpower
  • Publication number: 20240269372
    Abstract: In one aspect, a method is provided herein of preparing a drug delivery device, the drug delivery device having a body with at least one fluid duct being open along a first face of the body, the at least one fluid duct for conveying drug from at least one reservoir to a needle configured for injection into a patient, the method including: providing a barrier across the first face of the body to at least cover the at least one fluid duct, wherein the barrier is ultraviolet transmissive; and, exposing the first face of the body to ultraviolet radiation so as to allow the ultraviolet radiation to pass through the barrier and decontaminate the at least one fluid duct.
    Type: Application
    Filed: June 13, 2022
    Publication date: August 15, 2024
    Inventors: Martin John McLoughlin, Mark Steven Howansky, George Tyler Currier, Peter William Heyman, Yuhong Wu, Erinc Sahin, Shreya Shashank Kulkarni, Ankur Sagar Kulshrestha, Xiaodong Chen, John Christian Knutsen, James William Kidner Bradford, Simon Francis Brereton, Timothy Donald Barrow-Williams, Christopher William Rosier, Jeffrey Nicholas Philippson, Carys Eleri Lee, Paul Antony Merritt
  • Publication number: 20220395631
    Abstract: In one aspect, a drug delivery device is provided for delivering drug from a plurality of drug cartridges. The drug delivery device includes: a cylindrical cassette configured to accommodate the plurality of drug cartridges; a reversibly advanceable plunger; and, an indexer for incrementally rotating the cassette to align the plurality of drug cartridges individually with the plunger. The indexer includes first and second shafts with cooperating elements which cause incremental rotation of the first shaft, relative to the second shaft, upon the second shaft engaging the first shaft.
    Type: Application
    Filed: November 9, 2020
    Publication date: December 15, 2022
    Inventors: Martin John McLoughlin, Stephen Lawrence Zieminski, Peter William Heyman, Mark Steven Howansky, Frank Berardocco, Samuel Robert Zschack, Melanie Marie Springer, Jonathan Adam Reed, Joseph Morin
  • Publication number: 20220370289
    Abstract: Various embodiments are disclosed herein related to fluidic connections for modules useable in combinatorial drug delivery devices. The fluidic connections allow for variable flow paths to be defined for serially-connected, and base-tray mounted, modules.
    Type: Application
    Filed: November 9, 2020
    Publication date: November 24, 2022
    Inventors: Martin John McLoughlin, Stephen Lawrence Zieminski, Mark Steven Howansky, Frank Berardocco
  • Publication number: 20220362105
    Abstract: A valving arrangement is provided herein for regulating fluidics of modules usable in a combinatorial drug delivery device. The valving includes a slidable piston valve, adjustable to selectively seal an outlet path from a drug vial and a sealing port, in parallel to a vent, for selectively sealing an inlet path to the drug vial. Advantageously, the subject invention allows for applied negative pressure to adjust the valving to allow flow between serially-connected modules forming a drug delivery device.
    Type: Application
    Filed: November 9, 2020
    Publication date: November 17, 2022
    Inventors: Martin John McLoughlin, Stephen Lawrence Zieminski, Mark Steven Howansky, Mariano Mumpower, Melanie Marie Springer, Katherine Alina Goetz, Benjamin Richard Lane
  • Publication number: 20210154097
    Abstract: A combinatorial drug delivery device is provided for delivering a predetermined selection of drug components, each of the drug components being contained in a drug vial. The device includes a plurality of modules, wherein each of the modules includes: a body having an interior volume formed to accommodate a drug vial; a cannula protruding into the interior volume, the cannula terminating at a free end, first and second openings being formed in the free end with first and second lumens extending therefrom and through the cannula; a socket located on an exterior portion of the body; a first passageway extending between, and in communication with, the socket and the first lumen; a boss protruding from an exterior portion of the body; and, a second passageway extending from, and in communication with the second lumen, the second passageway extending through the boss to terminate at an exit opening formed therein.
    Type: Application
    Filed: May 10, 2019
    Publication date: May 27, 2021
    Inventors: Martin John McLoughlin, Mark Steven Howansky, Stephen Lawrence Zieminski, Chester Larrow, Mariano Mumpower