Patents by Inventor Mark Steven Shearman

Mark Steven Shearman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclohexyl sulphones for treatment of cancer
    Patent number: 8362075
    Abstract: Sulphones of formula (I) are disclosed for use in treatment of cancer.
    Type: Grant
    Filed: May 16, 2006
    Date of Patent: January 29, 2013
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Huw David Lewis, Timothy Harrison, Mark Steven Shearman
  • Sulphamides for treatment of cancer
    Patent number: 8242103
    Abstract: Bridged bicyclic sulphamides of formula (I) are disclosed for treatment of cancer.
    Type: Grant
    Filed: May 16, 2006
    Date of Patent: August 14, 2012
    Assignee: Merck Sharp & Dohme Limited
    Inventors: Huw David Lewis, Timothy Harrison, Mark Steven Shearman
  • CYCLOHEXYL SULPHONES FOR TREATMENT OF CANCER
    Publication number: 20100267801
    Abstract: Sulphones of formula (I) are disclosed for use in treatment of cancer.
    Type: Application
    Filed: May 16, 2006
    Publication date: October 21, 2010
    Inventors: Huw David Lewis, Timothy Harrison, Mark Steven Shearman
  • Sulphone Derivatives for Treatment of Cancer
    Publication number: 20090306058
    Abstract: Compounds of Formula (I) are disclosed for treatment of cancer.
    Type: Application
    Filed: May 16, 2006
    Publication date: December 10, 2009
    Inventors: Huw David Lewis, Timothy Harrison, Mark Steven Shearman
  • Sulphonamido-Substituted Cyclohexyl Sulphones for Treatment of Cancer
    Publication number: 20090215775
    Abstract: Compounds of formula (I) are disclosed for treatment of cancer.
    Type: Application
    Filed: May 16, 2006
    Publication date: August 27, 2009
    Inventors: Huw David Lewis, Timothy Harrison, Mark Steven Shearman
  • Sulphamides for Treatment of Cancer
    Publication number: 20090197904
    Abstract: Bridged bicyclic sulphamides of formula (I) are disclosed for treatment of cancer.
    Type: Application
    Filed: May 16, 2006
    Publication date: August 6, 2009
    Inventors: Huw David Lewis, Timothy Harrison, Mark Steven Shearman
  • Assay Method
    Publication number: 20080274476
    Abstract: There is disclosed a method for determining the activity of gamma-secretase in a text subject, using a biological sample from the subject.
    Type: Application
    Filed: December 8, 2005
    Publication date: November 6, 2008
    Inventors: Dirk Beher, Huw David Lewis, Mark Steven Shearman
  • Sulphonamido-substituted bridged bicycloalkyl derivatives
    Patent number: 7365196
    Abstract: A class of compounds is disclosed, comprising sulphonamido-substituted bridged bicycloalkyl structures. The compounds are inhibitors of gamma-secretase, and hence are useful in the treatment of and/or prevention of Alzheimer's disease.
    Type: Grant
    Filed: March 15, 2001
    Date of Patent: April 29, 2008
    Assignees: Merck Sharp & Dohme Ltd., Merck Frosst Canada & Co.
    Inventors: Patrice Charles Belanger, Ian James Collins, Joanne Claire Hannam, Timothy Harrison, Stephen John Lewis, Andrew Madin, Edward Giles McIver, Alan John Nadin, Joseph George Neduvelil, Mark Steven Shearman, Adrian Leonard Smith, Timothy Jason Sparey, Graeme Irvine Stevenson, Martin Richard Teall
  • Sulphonamido-substituted bridged bicycloalkyl derivatives
    Publication number: 20040029862
    Abstract: A class of compounds is disclosed, comprising sulphonamido-substituted bridged bicycloalkyl structures. The compounds are inhibitors of gamma-secretase, and hence are useful in the treatment of and/or prevention of Alzheimer's disease.
    Type: Application
    Filed: February 5, 2003
    Publication date: February 12, 2004
    Inventors: Patrice Charles Belanger, Ian James Collins, Joanne Claire Hannam, Timothy Harrison, Stephen John Lewis, Andrew Madin, Edward Giles McIver, Alan John Nadin, Joseph George Neduvelil, Mark Steven Shearman, Adrian Leonard Smith, Timothy Jason Sparey, Graeme Irvine Stevenson, Martin Richard Teall