Abstract: A method for ablating tissue by applying at least one pulse train of pulsed-field energy. The method includes delivering a pulse train of energy having a predetermined frequency to cardiac tissue, the pulse train including at least 60 pulses, an inter-phase delay between Ops and 5 ?s, an inter-pulse delay of at least 5 ?s, and a pulse width of 5 ?s.

Abstract: Two biomarkers are provided for obstructive apnea. A first biomarker determines amplitude and timing of inspiratory efforts from a bioelectric signal. The respiratory rate is compared with a normal pre-detection rate, and the amplitude of the effort is compared with a normal amplitude. The obstructive apnea is likely present if a series of inspiratory efforts are above a normal amplitude and with increasing amplitude, but at a normal rate. A second biomarker determines heart rate and respiratory rate. A normal lower threshold for heartbeat interval is established, and if subthreshold events occur (short RR intervals), a commencement time for each sequence of subthreshold events is compared for a respiratory rate-normalized window. If the number of subthreshold events exceeds a minimum for the window, obstructive apnea is likely present.

Abstract: Devices, systems and methods for altering functioning of a tissue/organ by application of force thereto. In one preferred embodiment, a device for reducing or preventing regurgitation of blood through a valve of a heart is provided. A device may include a main body having a segment adapted to apply force to a surface of tissue/organ and a member that applies counterforce to the force applied by the segment. Kits are provided in which devices having varying lengths and widths can be selected for the best fit for a particular location of treatment. A width sizing instrument may be provided. A length sizing instrument may be provided. A separate sleeve and/or pad may be provided which may be first anchored to the tissue/organ before fixing the device thereto.

Abstract: The invention provides a molecular classifier and a targeted sequencing assay for use in characterization and treatment of diffuse large B-cell lymphoma.

Abstract: A system and method for training a student employ a simulation station that displays output to the student and receives input. The computer system has a rules engine operating on it and computer accessible data storage storing (i) learning object data including learning objects configured to provide interaction with the student at the simulation system and (ii) rule data defining a plurality of rules accessed by the rules engine. The rules data includes, for each rule, respective (a) if-portion data defining a condition of data and (b) then-portion data defining an action to be performed at the simulation station. The rules engine causes the computer system to perform the action when the condition of data is present in the data storage. For at least some of the rules, the action comprises output of one of the learning objects so as to interact with the student. The system may be networked with middleware and adapters that map data received over the network to rules engine memory.

Abstract: A method for scan, try and/or buy may include receiving, from a mobile device, information that is representative of a clothing outfit. The clothing outfit may include a plurality of merchandise items available for purchase through a store. The information may be obtained by the mobile device by scanning a single code associated with the clothing outfit. The obtained information may be used to cause at least one user interface element associated with the clothing outfit to be displayed on the mobile device. In response to receiving a selection from the mobile device of the at least one user interface element, the plurality of merchandise items associated with the clothing outfit may be delivered to a merchandise check-out location within the store. The merchandise check-out location may be operable to receive payment from the user for the clothing outfit.

Abstract: A system and method for dosing SO2 into wine barrels is achieved with a device including a compressed gas cylinder containing compressed liquefied SO2 under its own vapor pressure, a dosing wand fluidly connected to the cylinder via a hose that is adapted and configured to allow a flow of gaseous SO2 from the source to the dosing wand. The dosing wand includes a hollow needle dispensing nozzle and a SO2 batch flow controller in fluid communication between the hose and the hollow needle. The hollow needle dispensing nozzle is adapted and configured to pierce through a bung opening of a wine barrel and has at least one aperture at a terminal end thereof to allow gaseous SO2 to be dispensed into an interior of the wine barrel.

Abstract: A method for ablating tissue by applying at least one pulse train of pulsed-field energy. The method includes delivering a pulse train of energy having a predetermined frequency to cardiac tissue, the pulse train including at least 60 pulses, an inter-phase delay between 0 ?s and 5 ?s, an inter-pulse delay of at least 5 ?s, and a pulse width of 5 ?s.

Abstract: A vaginal dilation device is provided that may include any of a number of features. One feature of the vaginal dilation device is that it is configured to dilate vaginal tissue during labor to prevent tissue damage. Another feature of the vaginal dilation device is that it can be manually controlled to dilate vaginal tissue, or can be automatically controlled to dilate vaginal tissue. In some embodiments, the vaginal dilation device is configured to measure a force applied by the device to tissue. In other embodiments, the vaginal dilation device is configured to apply a constant force to tissue. In other embodiments, the vaginal dilation device is configured to expand at a constant rate. Methods associated with use of the vaginal dilation device are also provided.

Abstract: Two biomarkers are provided for obstructive apnea. A first biomarker determines amplitude and timing of inspiratory efforts from a bioelectric signal. The respiratory rate is compared with a normal pre-detection rate, and the amplitude of the effort is compared with a normal amplitude. The obstructive apnea is likely present if a series of inspiratory efforts are above a normal amplitude and with increasing amplitude, but at a normal rate. A second biomarker determines heart rate and respiratory rate. A normal lower threshold for heartbeat interval is established, and if subthreshold events occur (short RR intervals), a commencement time for each sequence of subthreshold events is compared for a respiratory rate-normalized window. If the number of subthreshold events exceeds a minimum for the window, obstructive apnea is likely present.

Abstract: A method for ablating tissue by applying at least one pulse train of pulsed-field energy. The method includes delivering a pulse train of energy having a predetermined frequency to cardiac tissue, the pulse train including at least 60 pulses, an inter-phase delay between O?s and 5 ?s, an inter-pulse delay of at least 5 ?s, and a pulse width of 5 ?s.

Abstract: The present disclosure relates to a system for prevention of sudden death that includes a wearable seizure detection device; a base unit; and a computer, the computer configured to receive input from the seizure detection device and trigger the base unit to release oxygen under a condition effective to enrich an environmental oxygen level and prevent sudden death when the input indicates a seizure. Also disclosed is a portable system for preventing sudden death, where the system includes an oronasal mask; a compressed oxygen cartridge, wherein the compressed oxygen cartridge is coupled to the oronasal mask; and a fastener, wherein the fastener is coupled to the oronasal mask, wherein the system releases oxygen upon activation under a condition effective to enrich an environmental oxygen level and prevent sudden death. Further disclosed are methods of preventing sudden death comprising enriching an environmental oxygen level for a subject using the systems described.

Abstract: Associating a user service with a telephony identifier. The user service is accessible by a user of a telephony device via an application on the telephony device. The telephony device is operable in a radio telephony network (RTN) and is contactable via the telephony identifier when operating in the RTN. Network equipment: communicates, between the network equipment and the application on the telephony device, first data comprising a communicated token; receives, from the telephony device, second data comprising a received token, wherein the second data is received from the telephony device via an RTN-native service; receives, from a network node in the RTN, the telephony identifier in control signalling associated with the RTN-native service; and based at least on correlating the received token with the communicated token, associates the received telephony identifier with the user service.

Abstract: A foldable golf trolley comprising a chassis; at least one electrically powered rear drive wheel; a wheel support arm mounted to the front of the chassis supporting a front wheel; a stabilizer arm mounted to the rear of the chassis supporting a stabilizer wheel; a main support mounted to the chassis and a handle mounted to the main support; wherein the main support, the wheel support arm and the stabilizer arm are rotatably mounted to the chassis and movable between an operative configuration and a folded configuration; and gears connecting the stabilizer arm and main support, wherein rotation of the main support between the operative configuration and the folded configuration cause rotation of the stabilizer arm between the operative configuration and the folded configuration.

Abstract: A visual warning assembly, configured to make a warning from one vehicle to another vehicle. The visual warning assembly has a case with a front face joined to a base and an antenna. A channel display button, a channel selector button, a power button, a green lighted button, a yellow lighted button and a red lighted button, arranged on the front face. A mounting ball is magnetically joined to the base. A microcontroller is electrically coupled to the green lighted button, the yellow lighted button, and the red lighted button. The microcontroller is programmed with instructions to: receive a communication from a second visual warning assembly. Then, engage one member of a lighted button set consisting of the red button, the yellow button, and the green button creating an indicating light.

Abstract: A visual warning assembly, configured to make a warning from one vehicle to another vehicle. The visual warning assembly has a case with a front face joined to a base and an antenna. A channel display window, a channel selector button, a power button, a green lighted button, a yellow lighted button and a red lighted button, arranged on the front face. A mounting ball is magnetically joined to the base. A microcontroller is electrically coupled to the green lighted button, the yellow lighted button, and the red lighted button. The microcontroller is programmed with instructions to: receive a communication from a second visual warning assembly. Then, engage one member of a lighted button set consisting of the red button, the yellow button, and the green button creating an indicating light. Finally, receiving a signal from a user making the indicating light an activated button.

Abstract: A method of additively manufacturing an object comprises feeding a feedstock line into a delivery guide. The feedstock line has a length and comprises a continuous flexible line. The continuous flexible line has a peripheral surface. The feedstock line further comprises a covering, releasably coupled to the peripheral surface of the continuous flexible line. The method also comprises removing the covering from the peripheral surface of the continuous flexible line before the continuous flexible line is deposited along a print path and depositing the continuous flexible line along the print path using the delivery guide.

Abstract: Systems for thermal control of additive manufacturing comprise a build volume within which a part is additively manufactured; a heat source positioned relative to the build volume and configured to actively deliver heat to discrete sections of the part as it is being additively manufactured; and a controller operatively coupled to the heat source and configured to direct delivery of heat from the heat source to discrete sections of the part as it is being additively manufactured to impart desired physical properties to the part. Methods of additively manufacturing a part comprise additively building a part from a feedstock material; and actively heating discrete sections of the part as the part is being additively built to impart desired physical properties to the part.

Abstract: Described herein is a transport system and method of transporting objects including people between locations. The description also relates to urban and public transport systems for moving large numbers of people and freight or objects between locations. The description also relates to transport systems based on cable and rail elements and moving therebetween. Also described are junction mechanisms, switching and control systems.