Patents by Inventor Mark Stochl

Mark Stochl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLY-PEGYLATED PROTEASE INHIBITORS
    Publication number: 20120322744
    Abstract: Disclosed are compounds that comprise: (i) a Kunitz domain polypeptide that comprises a Kunitz domain that binds to and inhibits a protease; and (ii) a plurality of polyethylene glycol moieties attached to the Kunitz domain polypeptide. Each accessible primary amine of the Kunitz domain polypeptide can be attached to one of the moieties. Also disclosed are related methods.
    Type: Application
    Filed: May 3, 2012
    Publication date: December 20, 2012
    Applicant: DYAX CORP.
    Inventors: Arthur C. Ley, Aaron K. Sato, Robert C. Ladner, Mark Stochl
  • Poly-Pegylated Protease Inhibitors
    Publication number: 20110172140
    Abstract: Disclosed are compounds that comprise: (i) a Kunitz domain polypeptide that comprises a Kunitz domain that binds to and inhibits a protease; and (ii) a plurality of polyethylene glycol moieties attached to the Kunitz domain polypeptide. Each accessible primary amine of the Kunitz domain polypeptide can be attached to one of the moieties. Also disclosed are related methods.
    Type: Application
    Filed: May 26, 2009
    Publication date: July 14, 2011
    Applicant: Dyax Corp.
    Inventors: Arthur C. Ley, Aaron K. Sato, Robert C. Ladner, Mark Stochl
  • Poly-pegylated protease inhibitors
    Patent number: 7550427
    Abstract: Disclosed are compounds that comprise: (i) a Kunitz domain polypeptide that comprises a Kunitz domain that binds to and inhibits a protease; and (ii) a plurality of polyethylene glycol moieties attached to the Kunitz domain polypeptide. Each accessible primary amine of the Kunitz domain polypeptide can be attached to one of the moieties. Also disclosed are related methods.
    Type: Grant
    Filed: July 20, 2006
    Date of Patent: June 23, 2009
    Assignee: Dyax Corp.
    Inventors: Arthur C. Ley, Aaron K Sato, Robert C. Ladner, Mark Stochl
  • POLY-PEGYLATED PROTEASE INHIBITORS
    Publication number: 20070041959
    Abstract: Disclosed are compounds that comprise: (i) a Kunitz domain polypeptide that comprises a Kunitz domain that binds to and inhibits a protease; and (ii) a plurality of polyethylene glycol moieties attached to the Kunitz domain polypeptide. Each accessible primary amine of the Kunitz domain polypeptide can be attached to one of the moieties. Also disclosed are related methods.
    Type: Application
    Filed: July 20, 2006
    Publication date: February 22, 2007
    Inventors: Arthur Ley, Aaron Sato, Robert Ladner, Mark Stochl
  • Poly-pegylated protease inhibitors
    Publication number: 20050089515
    Abstract: Disclosed are compounds that comprise: (i) a Kunitz domain polypeptide that comprises a Kunitz domain that binds to and inhibits a protease; and (ii) a plurality of polyethylene glycol moieties attached to the Kunitz domain polypeptide. Each accessible primary amine of the Kunitz domain polypeptide can be attached to one of the moieties. Also disclosed are related methods.
    Type: Application
    Filed: August 30, 2004
    Publication date: April 28, 2005
    Inventors: Arthur Ley, Aaron Sato, Robert Ladner, Mark Stochl
  • Binding molecules for Fc-region polypeptides
    Publication number: 20030199671
    Abstract: Binding molecules for detecting or isolating immunoglobulin Fc-region polypeptides are described, together with methods of use thereof. Preferred Fc-region binding polypeptides, recombinant bacteriophage expressing Fc-region binding polypeptides, and separation media exhibiting such polypeptides are particularly disclosed.
    Type: Application
    Filed: April 18, 2002
    Publication date: October 23, 2003
    Inventors: Isaac Jesus Rondon, Qi-Long Wu, Arthur C. Ley, Mark Stochl, Thomas C. Ransohoff, M. Daniel Potter, Marilou Potter