Abstract: An implantable medical lead may include an electrode at a distal portion of the lead that is configured to monitor or provide therapy to a target site. The lead may include a visible indicator that is visible to the naked eye of a clinician at a medial portion of the lead that is configured to indicate when the electrodes of the lead are longitudinally and radially aligned properly to monitor or treat the target site. A clinician may insert the lead into the patient using an introducer sheath inserted to a predetermined depth into the patient and subsequently aligning the distal portion of the lead by orienting the indicator at an entry port of the introducer sheath.

Abstract: An exhaust gas heater system for an exhaust system of an internal combustion engine includes a housing and a heating element. The housing includes an outer peripheral wall disposed about a central axis and defining an interior hollow space configured to receive exhaust gas from an exhaust pipe of the exhaust system such that the exhaust gas flows through the interior hollow space. The heating element is positioned within the hollow space and including a first end and a second end. The heating element forms a zig-zag shape extending in a radial direction relative to the central axis.

Abstract: The present invention relates to genetically modified B cells and their uses thereof, for example, for the treatment of a variety of diseases and disorders, including cancer, heart disease, inflammatory disease, muscle wasting disease, neurological disease, and the like. In certain embodiments, the invention relates to an isolated modified B cell (“CAR-B cell), capable of expressing a chimeric receptor (“CAR-B receptor”), wherein said chimeric receptor comprises (a) an extracellular domain; (b) a transmembrane domain; and (c) a cytoplasmic domain that comprises at least one signaling domain. In various embodiments, the invention comprises an isolated modified B cell, wherein said B cell is capable of expressing and secreting a payload, wherein the payload is not naturally expressed in a B cell or is expressed at higher levels than is naturally expressed in a B cell. In various embodiments, the payload is an antibody or fragment thereof.

Abstract: A high-temperature bipolar battery consisting of a plurality of stacked individual cells. A first, thermal-sprayed electrode or electrolyte resistant material ceramic layer is sprayed to the exterior of the face-to-face stacked array and onto the peripheral faces of the battery metal end plates remote from the individual cells of a thickness sufficient to virtually eliminate all through pores therein. A second thermal-sprayed ceramic layer is of a thickness sufficient to form a metal support and containment structure of the bipolar battery stack. The thermal-sprayed layers have similar coefficients of thermal expansion (CTE). A metal cup surrounds and encloses at least one of the electrodes of each individual cell tending to form an inter-cell seal between the thermal-sprayed ceramic layer and the metal cup to prevent communication of electrolyte from cell to cell.

Abstract: Thermal batteries comprise an anode of alkali or alkaline earth metal and a fluorocarbon polymer of fluorochlorocarbon polymer depolarizer.

Abstract: Ferric sulfate is added to the iron pyrite depolarizer of a thermal battery to provide a predetermined voltage transient on activation of the battery.