Patents by Inventor Mark Tapsak
Mark Tapsak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 7761130Abstract: Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure analyte or non-analyte related signal, both of which electrode include an interference domain.Type: GrantFiled: March 27, 2007Date of Patent: July 20, 2010Assignee: DexCom, Inc.Inventors: Peter C. Simpson, James H. Brauker, Paul V. Goode, Apurv U. Kamath, James R. Petisce, Kum Ming Woo, Melissa A. Nicholas, Robert J. Boock, Monica A. Rixman, John Burd, Rathbun K. Rhodes, Mark A. Tapsak
-
Publication number: 20100160760Abstract: Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices include unique architectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.Type: ApplicationFiled: January 28, 2010Publication date: June 24, 2010Applicant: DexCom, Inc.Inventors: Mark C. Shults, Stuart J. Updike, Rathbun K. Rhodes, Barbara J. Gilligan, Mark A. Tapsak
-
Publication number: 20100145172Abstract: The present invention relates generally to systems and methods for increasing oxygen availability to implantable devices. The preferred embodiments provide a membrane system configured to provide protection of the device from the biological environment and/or a catalyst for enabling an enzymatic reaction, wherein the membrane system includes a polymer formed from a high oxygen soluble material. The high oxygen soluble polymer material is disposed adjacent to an oxygen-utilizing source on the implantable device so as to dynamically retain high oxygen availability to the oxygen-utilizing source during oxygen deficits. Membrane systems of the preferred embodiments are useful for implantable devices with oxygen-utilizing sources and/or that function in low oxygen environments, such as enzyme-based electrochemical sensors and cell transplantation devices.Type: ApplicationFiled: January 15, 2010Publication date: June 10, 2010Applicant: DexCom, Inc.Inventors: James Petisce, Mark A. Tapsak, Peter C. Simpson, Victoria Carr-Brendel, James H. Brauker
-
Publication number: 20100119693Abstract: The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.Type: ApplicationFiled: January 15, 2010Publication date: May 13, 2010Applicant: DexCom, Inc.Inventors: Mark A. Tapsak, Rathbun K. Rhodes, Mark C. Shults, Jason D. McClure
-
Publication number: 20100087724Abstract: The present invention provides a biointerface membrane for use with an implantable device that interferes with the formation of a barrier cell layer including; a first domain distal to the implantable device wherein the first domain supports tissue attachment and interferes with barrier cell layer formation and a second domain proximal to the implantable device wherein the second domain is resistant to cellular attachment and is impermeable to cells. In addition, the present invention provides sensors including the biointerface membrane, implantable devices including these sensors or biointerface membranes, and methods of monitoring glucose levels in a host utilizing the analyte detection implantable device of the invention. Other implantable devices which include the biointerface membrane of the present invention, such as devices for cell transplantation, drug delivery devices, and electrical signal delivery or measuring devices are also provided.Type: ApplicationFiled: December 8, 2009Publication date: April 8, 2010Applicant: DexCom, Inc.Inventors: James H. Brauker, Mark Shults, Mark A. Tapsak
-
Patent number: 7693560Abstract: Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure analyte or non-analyte related signal, both of which electrode include an interference domain.Type: GrantFiled: March 27, 2007Date of Patent: April 6, 2010Assignee: DexCom, Inc.Inventors: Peter C. Simpson, James H. Brauker, Paul V. Goode, Apurv U. Kamath, James R. Petisce, Kum Ming Woo, Melissa A. Nicholas, Robert J. Boock, Monica A. Rixman, John Burd, Rathburn K. Rhodes, Mark A. Tapsak
-
Publication number: 20100041971Abstract: An implantable analyte sensor including a sensing region for measuring the analyte and a non-sensing region for immobilizing the sensor body in the host. The sensor is implanted in a precisely dimensioned pocket to stabilize the analyte sensor in vivo and enable measurement of the concentration of the analyte in the host before and after formation of a foreign body capsule around the sensor. The sensor further provides a transmitter for RF transmission through the sensor body, electronic circuitry, and a power source optimized for long-term use in the miniaturized sensor body.Type: ApplicationFiled: October 29, 2009Publication date: February 18, 2010Applicant: DexCom, Inc.Inventors: Paul V. Goode, JR., Arnold L. Holmquist, Mark A. Tapsak, Mark Shults, Victoria Carr-Brendel, James H. Brauker, Paul V. Neale, Jason D. McClure, Mark Brister, Peter C. Simpson, Rathbun K. Rhodes
-
Patent number: 7632228Abstract: The present invention provides a biointerface membrane for use with an implantable device that interferes with the formation of a barrier cell layer including; a first domain distal to the implantable device wherein the first domain supports tissue attachment and interferes with barrier cell layer formation and a second domain proximal to the implantable device wherein the second domain is resistant to cellular attachment and is impermeable to cells. In addition, the present invention provides sensors including the biointerface membrane, implantable devices including these sensors or biointerface membranes, and methods of monitoring glucose levels in a host utilizing the analyte detection implantable device of the invention. Other implantable devices which include the biointerface membrane of the present invention, such as devices for cell transplantation, drug delivery devices, and electrical signal delivery or measuring devices are also provided.Type: GrantFiled: January 29, 2004Date of Patent: December 15, 2009Assignee: DexCom, Inc.Inventors: James H. Brauker, Mark C. Shults, Mark A. Tapsak
-
Publication number: 20090299276Abstract: Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.Type: ApplicationFiled: August 6, 2009Publication date: December 3, 2009Applicant: DexCom, Inc.Inventors: James H. Brauker, Mark A. Tapsak, Sean T. Saint, Apurv U. Kamath, Paul V. Neale, Peter C. Simpson, Michael Robert Mensinger, Dubravka Markovic
-
Patent number: 7591801Abstract: Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.Type: GrantFiled: February 26, 2004Date of Patent: September 22, 2009Assignee: Dexcom, Inc.Inventors: James H. Brauker, Mark A. Tapsak, Sean T. Saint, Apurv U. Kamath, Paul V. Neale, Peter C. Simpson, Michael Robert Mensinger, Dubravka Markovic
-
Publication number: 20090076356Abstract: Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure analyte or non-analyte related signal, both of which electrode include an interference domain.Type: ApplicationFiled: November 3, 2008Publication date: March 19, 2009Applicant: DexCom, Inc.Inventors: Peter C. Simpson, James H. Brauker, Paul V. Goode, Apurv U. Kamath, James R. Petisce, Kum Ming Woo, Melissa A. Nicholas, Robert J. Boock, Monica A. Rixman, John Burd, Rathburn K. Rhodes, Mark A. Tapsak
-
Publication number: 20090062633Abstract: An implantable analyte sensor including a sensing region for measuring the analyte and a non-sensing region for immobilizing the sensor body in the host. The sensor is implanted in a precisely dimensioned pocket to stabilize the analyte sensor in vivo and enable measurement of the concentration of the analyte in the host before and after formation of a foreign body capsule around the sensor. The sensor further provides a transmitter for RF transmission through the sensor body, electronic circuitry, and a power source optimized for long-term use in the miniaturized sensor body.Type: ApplicationFiled: November 4, 2008Publication date: March 5, 2009Applicant: DexCorn, Inc.Inventors: James H. Brauker, Mark A. Tapsak, Mark Shults, Victoria Carr-Brendel, Jack C. Fisher, William J. Seare, JR., Paul V. Neale
-
Publication number: 20090045055Abstract: The present invention provides a sensor head for use in an implantable device that measures the concentration of an analyte in a biological fluid which includes: a non-conductive body; a working electrode, a reference electrode and a counter electrode, wherein the electrodes pass through the non-conductive body forming an electrochemically reactive surface at one location on the body and forming an electronic connection at another location on the body, further wherein the electrochemically reactive surface of the counter electrode is greater than the surface area of the working electrode; and a multi-region membrane affixed to the nonconductive body and covering the working electrode, reference electrode and counter electrode. In addition, the present invention provides an implantable device including at least one of the sensor heads of the invention and methods of monitoring glucose levels in a host utilizing the implantable device of the invention.Type: ApplicationFiled: October 28, 2008Publication date: February 19, 2009Applicant: DexCom, Inc.Inventors: Rathbun K. Rhodes, Mark C. Shults, Mark A. Tapsak, James H. Brauker
-
Patent number: 7471972Abstract: The present invention provides a sensor head for use in an implantable device that measures the concentration of an analyte in a biological fluid which includes: a non-conductive body; a working electrode, a reference electrode and a counter electrode, wherein the electrodes pass through the non-conductive body forming an electrochemically reactive surface at one location on the body and forming an electronic connection at another location on the body, further wherein the electrochemically reactive surface of the counter electrode is greater than the surface area of the working electrode; and a multi-region membrane affixed to the nonconductive body and covering the working electrode, reference electrode and counter electrode. In addition, the present invention provides an implantable device including at least one of the sensor heads of the invention and methods of monitoring glucose levels in a host utilizing the implantable device of the invention.Type: GrantFiled: December 22, 2004Date of Patent: December 30, 2008Assignee: DexCom, Inc.Inventors: Rathbun Rhodes, Mark A. Tapsak, James H. Brauker, Mark C. Shults
-
Publication number: 20080228051Abstract: An implantable analyte-measuring device including a membrane adapted to promote vascularization and/or interfere with barrier cell layer formation. The membrane includes any combination of materials, architecture, and bioactive agents that facilitate analyte transport to provide long-term in vivo performance of the implantable analyte-measuring device.Type: ApplicationFiled: February 26, 2008Publication date: September 18, 2008Applicant: DexCom. Inc.Inventors: Mark C. Shults, James H. Brauker, Victoria Carr-Brendel, Mark A. Tapsak, Dubravka Markovic, Stuart J. Updike, Rathbun K. Rhodes
-
Publication number: 20080228054Abstract: An implantable analyte-measuring device including a membrane adapted to promote vascularization and/or interfere with barrier cell layer formation. The membrane includes any combination of materials, architecture, and bioactive agents that facilitate analyte transport to provide long-term in vivo performance of the implantable analyte-measuring device.Type: ApplicationFiled: February 26, 2008Publication date: September 18, 2008Applicant: DexCom, Inc.Inventors: Mark C. Shults, James H. Brauker, Victoria Carr-Brendel, Mark A. Tapsak, Dubravka Markovic, Stuart J. Updike, Rathbun K. Rhodes
-
Patent number: 7379765Abstract: The present invention relates generally to systems and methods for increasing oxygen availability to implantable devices. The preferred embodiments provide a membrane system configured to provide protection of the device from the biological environment and/or a catalyst for enabling an enzymatic reaction, wherein the membrane system includes a polymer formed from a high oxygen soluble material. The high oxygen soluble polymer material is disposed adjacent to an oxygen-utilizing source on the implantable device so as to dynamically retain high oxygen availability to the oxygen-utilizing source during oxygen deficits. Membrane systems of the preferred embodiments are useful for implantable devices with oxygen-utilizing sources and/or that function in low oxygen environments, such as enzyme-based electrochemical sensors and cell transplantation devices.Type: GrantFiled: July 21, 2004Date of Patent: May 27, 2008Assignee: DexCom, Inc.Inventors: James Petisce, Mark A. Tapsak, Peter C. Simpson, Victoria Carr-Brendel, James H. Brauker
-
Patent number: 7365134Abstract: Compounds that include silicon-containing groups, and optionally urethane groups, urea groups, or combinations thereof (i.e., polyurethanes, polyureas, or polyurethane-ureas), as well as materials and methods for making such compounds.Type: GrantFiled: May 20, 2005Date of Patent: April 29, 2008Assignee: Medtronic, IncInventors: Michael Eric Benz, Christopher M. Hobot, David L. Miller, David A. Pearson, Mark A. Tapsak, Edward DiDomenico, Randall V. Sparer
-
Publication number: 20080045824Abstract: The present invention relates generally to biosensor materials. More specifically, this invention relates to a novel polymeric material that can be useful as a biocompatible membrane for use in biosensor applications.Type: ApplicationFiled: June 14, 2007Publication date: February 21, 2008Applicant: DexCom, Inc.Inventors: Mark Tapsak, Paul Valint
-
Publication number: 20070213611Abstract: Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure analyte or non-analyte related signal, both of which electrode include an interference domain.Type: ApplicationFiled: March 27, 2007Publication date: September 13, 2007Inventors: Peter Simpson, James Brauker, Paul Goode, Apurv Kamath, James Petisce, Kum Woo, Melissa Nicholas, Robert Boock, Monica Rixman, John Burd, Rathbun Rhodes, Mark Tapsak