Patents by Inventor Mark Tempest

Mark Tempest has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-oxa-1-azabicyclo [3,2,0] heptan-7-one derivatives as antitumor agents
    Patent number: 5561126
    Abstract: The present invention relates to the use of 4-oxa-1-azabicyclo [3,2,0] heptan-7-one derivatives of formula (I) or a pharmaceutically acceptable salt thereof, as antitumor agents. ##STR1## Wherein R is --OCOR.sub.1 group wherein R.sub.1 is hydrogen atom, a C.sub.1-9 alkyl group which may be substituted by either one or two substituents selected together from halogen atom, hydroxy, carboxy group or (3RS,5SR)-(4-oxo-1-azabicyclo[3,2,0]heptan-7-one-3-yl) methyloxycarbonyl, a C.sub.2-17 alkenyl group, which may be substituted by carboxy group or (3RS,5SR)-(4-oxa-1-azabicyclo [3,2,0]heptan-7-one-3-yl)methyloxycarbonyl, A C.sub.2-4 alkynyl group, a C.sub.3-6 cycloalkyl group which may be substituted by carboxy group or phenyl group which may have 1, 2 or 3 substituents selected from the group consisting of cyano group, halogen atom, C.sub.1-6 alkoxy group which may be substituted by carboxy group, C.sub.1-6 alkyl group, amino group or hydroxy group.--OR.sub.2 wherein R.sub.
    Type: Grant
    Filed: March 16, 1995
    Date of Patent: October 1, 1996
    Assignees: Taiho Pharmaceutical Co., Ltd., Synphar Laboratories, Inc.
    Inventors: Toshio Otani, Shinji Oie, Hiroshi Matsumoto, Mark Tempest, Ronald Micetich, Rajeshwar Singh, Tomohiro Yamashita