Patents by Inventor Mark Tepper
Mark Tepper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20220117931Abstract: This application is in the field of medicinal chemistry and relates to ultrapure ajulemic acid, its synthesis, pharmaceutical compositions and methods of use thereof for the treatment and/or prevention of inflammation, pain, and fibrotic diseases including scleroderma, systemic sclerosis, scleroderma-like disorders, sine scleroderma, liver cirrhosis, interstitial pulmonary fibrosis, idiopathic pulmonary fibrosis, Dupuytren's contracture, keloids, chronic kidney disease, chronic graft rejection, and other scarring-wound healing abnormalities, post-operative adhesions, and reactive fibrosis.Type: ApplicationFiled: June 2, 2021Publication date: April 21, 2022Inventors: Mark TEPPER, Dean A. FREY, David GOEDDEL, Karl E. REINEKE
-
Publication number: 20210401798Abstract: The invention relates to (S)-6-((1 R,2E,4E,8E,10S)-11-(4-fluorophenoxy)-1,10-dihydroxyundeca-2,4,8-trien-6-yn-1-yl)-1,4-dioxan-2-one (compound (1)), which is a lactone-containing analog of lipoxin A4 (LXA4). In particular, the invention features pharmaceutical compositions including compound (1) and the use of compound (1) for the treatment of a disorder (e.g., a fibrotic disorder or an inflammatory disorder, such as an autoimmune disorder) in a subject in need thereof.Type: ApplicationFiled: October 23, 2019Publication date: December 30, 2021Applicants: The Brigham and Women's Hospital, Inc., Corbus Pharmaceuticals, Inc., Corbus Pharmaceuticals, Inc.Inventors: Nan CHIANG, Sheldon N. CRANE, Thomas JENNEQUIN, Valdas JURKAUSKAS, Clifton D. LEIGH, Kristos Adrian MOSHOS, Charles N. Serhan, Mark A. Tepper, Yuhua George Zhang
-
Publication number: 20210284621Abstract: The invention relates to cannabinoid compounds, pharmaceutical compositions including one or more cannabinoid compounds, and the use of pharmaceutical compositions including one or more cannabinoid compounds for the treatment of a disease or condition (e.g., a fibrotic disease or an inflammatory disease) in a subject in need thereof.Type: ApplicationFiled: May 31, 2019Publication date: September 16, 2021Inventors: Kristos Adrian MOSHOS, Clifton D. LEIGH, Yuhua George ZHANG, Mark TEPPER, Hongfeng DENG
-
Patent number: 11052066Abstract: This application is in the field of medicinal chemistry and relates to ultrapure ajulemic acid, its synthesis, pharmaceutical compositions and methods of use thereof for the treatment and/or prevention of inflammation, pain, and fibrotic diseases including scleroderma, systemic sclerosis, scleroderma-like disorders, sine scleroderma, liver cirrhosis, interstitial pulmonary fibrosis, idiopathic pulmonary fibrosis, Dupuytren's contracture, keloids, chronic kidney disease, chronic graft rejection, and other scarring-wound healing abnormalities, post-operative adhesions, and reactive fibrosis.Type: GrantFiled: May 29, 2019Date of Patent: July 6, 2021Assignee: Corbus Pharmaceuticals, Inc.Inventors: Mark Tepper, Dean A. Frey, David Goeddel, Karl E. Reineke
-
Publication number: 20200405687Abstract: The invention provides methods for treating an infection in a subject in need thereof by administering to the subject a pharmaceutical composition including ajulcmic acid, or a pharmaceutically acceptable salt thereof. In various embodiments, the infection may be a bacterial, viral, or fungal infection. The invention also features methods of treating an infection in a subject in need thereof by administering to the subject ajulemic acid, or a pharmaceutically acceptable salt thereof, and a suitable antibiotic, antifungal, or antiviral.Type: ApplicationFiled: January 31, 2020Publication date: December 31, 2020Inventors: Mark A. TEPPER, Derek W. GILROY, Madhur MOTWANI, Tracey L. BONFIELD
-
Publication number: 20200093784Abstract: This application is in the field of medicinal chemistry and relates to ultrapure ajulemic acid, its synthesis, pharmaceutical compositions and methods of use thereof for the treatment and/or prevention of inflammation, pain, and fibrotic diseases including scleroderma, systemic sclerosis, scleroderma-like disorders, sine scleroderma, liver cirrhosis, interstitial pulmonary fibrosis, idiopathic pulmonary fibrosis, Dupuytren's contracture, keloids, chronic kidney disease, chronic graft rejection, and other scarring-wound healing abnormalities, post-operative adhesions, and reactive fibrosis.Type: ApplicationFiled: May 29, 2019Publication date: March 26, 2020Inventors: Mark TEPPER, Dean A. FREY, David GOEDDEL, Karl E. REINEKE
-
Patent number: 10470979Abstract: An intelligent pacifier estimates its state based on one or more sensors. Based on the estimated state, the pacifier may provide an alert or notification to a child or caretaker regarding the state of the child. The alert or notification may be generated by one or more output transducers and may increase in level depending on the estimated state. An application program communicates with the intelligent pacifier, allowing the caretaker to review and analyze the data collected by the intelligent pacifier, and to configure the intelligent pacifier. Embodiments of the intelligent pacifier may vary in the number and type of sensors, the number and type of estimated states, and the number and type of output transducers. The intelligent pacifier may be constructed as a single device or may consist of a housing that interfaces to a typical pacifier.Type: GrantFiled: January 24, 2017Date of Patent: November 12, 2019Assignee: HIVE DESIGN, INC.Inventors: Mark Tepper, Lesley Tepper, Loren Vittetoe, Andrew Straub, Shane Rogers
-
Patent number: 10369131Abstract: This application is in the field of medicinal chemistry and relates to ultrapure ajulemic acid, its synthesis, pharmaceutical compositions and methods of use thereof for the treatment and/or prevention of inflammation, pain, and fibrotic diseases including scleroderma, systemic sclerosis, scleroderma-like disorders, sine scleroderma, liver cirrhosis, interstitial pulmonary fibrosis, idiopathic pulmonary fibrosis, Dupuytren's contracture, keloids, chronic kidney disease, chronic graft rejection, and other scarring-wound healing abnormalities, post-operative adhesions, and reactive fibrosis.Type: GrantFiled: November 21, 2018Date of Patent: August 6, 2019Assignee: Corbus Pharmaceuticals, Inc.Inventors: Mark Tepper, Dean A. Frey, David Goeddel, Karl E. Reineke
-
Publication number: 20190133995Abstract: The invention provides methods for treating an infection in a subject in need thereof by administering to the subject a pharmaceutical composition including ajulemic acid, or a pharmaceutically acceptable salt thereof. In various embodiments, the infection may be a bacterial, viral, or fungal infection. The invention also features methods of treating an infection in a subject in need thereof by administering to the subject ajulemic acid, or a pharmaceutically acceptable salt thereof, and a suitable antibiotic, antifungal, or antiviral.Type: ApplicationFiled: April 28, 2017Publication date: May 9, 2019Inventors: Mark A. TEPPER, Derek W. GILROY, Madhur MOTWANI, Tracey L. BONFIELD
-
Publication number: 20190091200Abstract: This application is in the field of medicinal chemistry and relates to ultrapure ajulemic acid, its synthesis, pharmaceutical compositions and methods of use thereof for the treatment and/or prevention of inflammation, pain, and fibrotic diseases including scleroderma, systemic sclerosis, scleroderma-like disorders, sine scleroderma, liver cirrhosis, interstitial pulmonary fibrosis, idiopathic pulmonary fibrosis, Dupuytren's contracture, keloids, chronic kidney disease, chronic graft rejection, and other scarring-wound healing abnormalities, post-operative adhesions, and reactive fibrosis.Type: ApplicationFiled: November 21, 2018Publication date: March 28, 2019Inventors: Mark TEPPER, Dean A. FREY, David GOEDDEL, Karl E. REINEKE
-
Patent number: 10154986Abstract: This application is in the field of medicinal chemistry and relates to ultrapure ajulemic acid, its synthesis, pharmaceutical compositions and methods of use thereof for the treatment and/or prevention of inflammation, pain, and fibrotic diseases including scleroderma, systemic sclerosis, scleroderma-like disorders, sine scleroderma, liver cirrhosis, interstitial pulmonary fibrosis, idiopathic pulmonary fibrosis, Dupuytren's contracture, keloids, chronic kidney disease, chronic graft rejection, and other scarring-wound healing abnormalities, post-operative adhesions, and reactive fibrosis.Type: GrantFiled: September 7, 2017Date of Patent: December 18, 2018Assignee: Corbus Pharmaceuticals, Inc.Inventors: Mark Tepper, Dean A. Frey, David Goeddel, Karl E. Reineke
-
Patent number: 10085964Abstract: This application is in the field of medicinal chemistry and relates to ultrapure ajulemic acid, its synthesis, pharmaceutical compositions and methods of use thereof for the treatment and/or prevention of inflammation, pain, and fibrotic diseases including scleroderma, systemic sclerosis, scleroderma-like disorders, sine scleroderma, liver cirrhosis, interstitial pulmonary fibrosis, idiopathic pulmonary fibrosis, Dupuytren's contracture, keloids, chronic kidney disease, chronic graft rejection, and other scarring-wound healing abnormalities, post-operative adhesions, and reactive fibrosis.Type: GrantFiled: July 26, 2016Date of Patent: October 2, 2018Assignee: Corbus Pharmaceuticals, Inc.Inventors: Mark Tepper, Dean A. Frey, David Goeddel, Karl E. Reineke
-
Publication number: 20180207065Abstract: An intelligent pacifier estimates its state based on one or more sensors. Based on the estimated state, the pacifier may provide an alert or notification to a child or caretaker regarding the state of the child. The alert or notification may be generated by one or more output transducers and may increase in level depending on the estimated state. An application program communicates with the intelligent pacifier, allowing the caretaker to review and analyze the data collected by the intelligent pacifier, and to configure the intelligent pacifier. Embodiments of the intelligent pacifier may vary in the number and type of sensors, the number and type of estimated states, and the number and type of output transducers. The intelligent pacifier may be constructed as a single device or may consist of a housing that interfaces to a typical pacifier.Type: ApplicationFiled: January 24, 2017Publication date: July 26, 2018Applicant: Baby Goose LLCInventors: Mark Tepper, Lesley Tepper, Loren Vittetoe, Andrew Straub, Shane Rogers
-
Publication number: 20180177757Abstract: This application is in the field of medicinal chemistry and relates to ultrapure ajulemic acid, its synthesis, pharmaceutical compositions and methods of use thereof for the treatment and/or prevention of inflammation, pain, and fibrotic diseases including scleroderma, systemic sclerosis, scleroderma-like disorders, sine scleroderma, liver cirrhosis, interstitial pulmonary fibrosis, idiopathic pulmonary fibrosis, Dupuytren's contracture, keloids, chronic kidney disease, chronic graft rejection, and other scarring-wound healing abnormalities, post-operative adhesions, and reactive fibrosis.Type: ApplicationFiled: September 7, 2017Publication date: June 28, 2018Inventor: Mark TEPPER
-
Patent number: 9820964Abstract: This application is in the field of medicinal chemistry and relates to ultrapure ajulemic acid, its synthesis, pharmaceutical compositions and methods of use thereof for the treatment and/or prevention of inflammation, pain, and fibrotic diseases including scleroderma, systemic sclerosis, scleroderma-like disorders, sine scleroderma, liver cirrhosis, interstitial pulmonary fibrosis, idiopathic pulmonary fibrosis, Dupuytren's contracture, keloids, chronic kidney disease, chronic graft rejection, and other scarring-wound healing abnormalities, post-operative adhesions, and reactive fibrosis.Type: GrantFiled: November 9, 2016Date of Patent: November 21, 2017Assignee: Corbus Pharmaceuticals, Inc.Inventor: Mark Tepper
-
Patent number: 9801849Abstract: This application is in the field of medicinal chemistry and relates to ultrapure ajulemic acid, its synthesis, pharmaceutical compositions and methods of use thereof for the treatment and/or prevention of inflammation, pain, and fibrotic diseases including scleroderma, systemic sclerosis, scleroderma-like disorders, sine scleroderma, liver cirrhosis, interstitial pulmonary fibrosis, idiopathic pulmonary fibrosis, Dupuytren's contracture, keloids, chronic kidney disease, chronic graft rejection, and other scarring-wound healing abnormalities, post-operative adhesions, and reactive fibrosis.Type: GrantFiled: November 9, 2016Date of Patent: October 31, 2017Assignee: Corbus Pharmaceuticals, Inc.Inventor: Mark Tepper
-
Publication number: 20170124586Abstract: Systems and methods are provided for providing a personalized prepaid card by receiving a user selection for designing a user-customized product and generating a first image of a personalized prepaid card having an image of the user-customized product, whereby the personalized prepaid card image is delivered to the user with an offer to receive the card in exchange for satisfying one or more conditions associated with the offer and providing the user with a unique identifier code associated with the offer to present the code to a retail establishment selling the user-customized product for activating the personalized prepaid card.Type: ApplicationFiled: October 28, 2016Publication date: May 4, 2017Inventors: Mark Tepper, John Boldebuck
-
Publication number: 20170071898Abstract: This application is in the field of medicinal chemistry and relates to ultrapure ajulemic acid, its synthesis, pharmaceutical compositions and methods of use thereof for the treatment and/or prevention of inflammation, pain, and fibrotic diseases including scleroderma, systemic sclerosis, scleroderma-like disorders, sine scleroderma, liver cirrhosis, interstitial pulmonary fibrosis, idiopathic pulmonary fibrosis, Dupuytren's contracture, keloids, chronic kidney disease, chronic graft rejection, and other scarring-wound healing abnormalities, post-operative adhesions, and reactive fibrosis.Type: ApplicationFiled: July 26, 2016Publication date: March 16, 2017Inventor: Mark Tepper
-
Publication number: 20170071900Abstract: This application is in the field of medicinal chemistry and relates to ultrapure ajulemic acid, its synthesis, pharmaceutical compositions and methods of use thereof for the treatment and/or prevention of inflammation, pain, and fibrotic diseases including scleroderma, systemic sclerosis, scleroderma-like disorders, sine scleroderma, liver cirrhosis, interstitial pulmonary fibrosis, idiopathic pulmonary fibrosis, Dupuytren's contracture, keloids, chronic kidney disease, chronic graft rejection, and other scarring-wound healing abnormalities, post-operative adhesions, and reactive fibrosis.Type: ApplicationFiled: November 9, 2016Publication date: March 16, 2017Inventor: Mark TEPPER
-
Publication number: 20170071899Abstract: This application is in the field of medicinal chemistry and relates to ultrapure ajulemic acid, its synthesis, pharmaceutical compositions and methods of use thereof for the treatment and/or prevention of inflammation, pain, and fibrotic diseases including scleroderma, systemic sclerosis, scleroderma-like disorders, sine scleroderma, liver cirrhosis, interstitial pulmonary fibrosis, idiopathic pulmonary fibrosis, Dupuytren's contracture, keloids, chronic kidney disease, chronic graft rejection, and other scarring-wound healing abnormalities, post-operative adhesions, and reactive fibrosis.Type: ApplicationFiled: November 9, 2016Publication date: March 16, 2017Inventor: Mark TEPPER