Abstract: The current invention pertains to nitroimidazooxazine and nitroimidazooxazole analogues, their methods of preparation, and uses of the compounds as treatment for Mycobacterium tuberculosis, for use as anti-tubercular drugs, for use as anti-protozoal agents with unexpectedly high potency against Trypanosoma cruzi or Leishmania donovani, and for the treatment of other microbial infections.

Abstract: A mug shot acquisition system is disclosed that includes an image acquisition interface that is operative to receive digital mug shot images from an imaging device. An image viewing display is responsive to the image acquisition interface and operative to display the received digital mug shot images. One or more standards-based image adjustment software tools allow the digital mug shot images to be adjusted to meet at least one predetermined mug shot image uniformity standard. The system also includes a software interface responsive to requests to initiate one or more operations by the mug shot acquisition system, and an image export interface operative to export digital mug shot images adjusted based on the standards-based image adjustment software.

Abstract: A process for the plasma-assisted treatment of coal in which coal is directly converted to heavy hydrocarbons. The first step in the process is direct conversion of coal to aliphatic hydrocarbons under plasma conditions in the presence of light hydrocarbons, such as natural gas. In the second process step, the aliphatic hydrocarbons are upgraded to a liquid fuel. The energy for the process can be provided by radio frequency energy, such as microwave energy, that is powered by a renewable energy source. The process has flexibility to adjust aromatic content in the fuel to match fuel specification requirements.

Abstract: A method for adjusting a controller of a scanner includes obtaining a scan of a predefined image. The method further includes moving the sensor-element signals of the control signal pattern generated by the controller earlier in the pattern by at least one unit and obtaining an additional scan. The obtaining and moving are repeated until a comparison of a latest additional scan to the image is worse than a comparison of a second-latest additional scan to the image. Another method obtains a noise-reducing heuristic which modifies a time parameter of a sensor-element signal. A set of repeated scans of a same scan line is obtained, noise is measured there from, the time parameter is modified by one predetermined unit, and the process repeats until the noise measured from the latest set of repeated scans is worse than that from the second-latest set of repeated scans.

Abstract: This invention pertains in part to the development of a vaccine for poultry against necrotic enteritis (NE). The vaccine utilizes a protective antigen that is a mutated, full-length, non-toxic Clostridium perfringens (Cp) ?-toxin protein (Mcpa). Utility of this vaccine was demonstrated by reduction of lesion severity in NE challenge trails, for example. Also disclosed herein are novel approaches for producing this vaccine in significant quantities. One exemplified approach involves producing NE vaccine (mutated alpha toxin) in bacterial expression systems, preferably utilizing the Pseudomonas fluorescens system, for commercial use in controlling NE in the poultry industry. The subject vaccines can be administered preferably to chickens in several different ways. A novel, Type VI alpha toxin from chicken isolates of Cp is also disclosed.

Abstract: An improved method, apparatus, and control/guiding software for localizing, characterizing, and correcting defects in integrated circuits, particularly open or resistive contact/via defects and metal bridging defects, using FIB technology. An apparatus for identifying an abnormal discontinuity in a contact/via in an integrated circuit comprising a focused ion beam system to scan the ion beam over the contact/via to do remove or deposit via material, a detector to collect a secondary particle signal from the contact/via material that gets removed, a sub-system for storing the secondary particle signal from the contact/via in time as well as x-y scan position, a sub-system for correlating secondary particle signals and identifying discontinuities in the correlated secondary particle signals, a sub-system for optimizing the display of the abnormal discontinuity; and a computer to implement software aspects of the system.

Abstract: A communications network (12) for use by a utility (10) for communication, command, and control of the utility's distribution area for gas, water and electrical services including the utility's distribution system, security, workforce, and asset management. The network includes apparatus for obtaining information and data concerning usage of the electricity, gas, or water by each of the utility's customers, the operation of installations throughout the system, and how electricity, gas, or water is being distributed throughout the system. The information and data from each source (16) is processed to provide an up-to-date overview of the system and its operation to the utility's management and operating personnel. This includes identification of any current problems, including distribution or security, within the system, and asset monitoring and management to identify possible future problems which may occur within a predetermined period of time.

Abstract: The present invention relates to the calibration of devices using a secondary binding agent or reference material. In one embodiment, the present invention provides a method of calibrating a nanosensor by providing a nanosensor comprising an analyte binder attached to a reference binder, extracting a calibration curve from binding a reference material to the reference binder, and calibrating the nanosensor by using the calibration curve to correct for device variation.

Abstract: One method involves the use of stored value account that may be used, for example, to make internet payments, and that can be credited using a variety of payment techniques. Such a method involves receiving money at a money transfer location from a potential purchaser. The money is then stored as an electronic record in a stored value account of the purchaser. This money is then available for transfer at the request of the purchaser. Upon such a request, the money may be electronically sent to a recipient and the stored value account may be debited.

Abstract: This invention pertains in part to the development of a vaccine for poultry against necrotic enteritis (NE). The vaccine utilizes a protective antigen that is a mutated, full-length, non-toxic Clostridium perfringens (Cp) ?-toxin protein (Mcpa). Utility of this vaccine was demonstrated by reduction of lesion severity in NE challenge trails, for example. Also disclosed herein are novel approaches for producing this vaccine in significant quantities. One exemplified approach involves producing NE vaccine (mutated alpha toxin) in bacterial expression systems, preferably utilizing the Pseudomonas fluorescens system, for commercial use in controlling NE in the poultry industry. The subject vaccines can be administered preferably to chickens in several different ways. A novel, Type VI alpha toxin from chicken isolates of Cp is also disclosed.

Abstract: Systems and methods of applying an ozone-depleting catalytic coating to an air stream component for producing a durable surface with optimal ozone depletion characteristics are provided. An air stream component having a surface with favorable adhesive properties or coatings is exposed to a concentration of ozone-depleting catalytic particles, wherein the receptive surface of the coated substrate binds the ozone-depleting catalytic coating.

Abstract: A system and method for measuring a thickness of a refractory wall of a gasifier using electromagnetic energy is disclosed. The system includes a waveguide with a bistatic or monostatic phased array antenna at one end. The waveguide is operably connected to a Network Analyzer that generates a pulse of electromagnetic energy with a desired bandwidth. The pulse is transmitted through a coaxial cable to the waveguide. The reflection of the pulse is received by the waveguide and input to a data acquisition system.

Abstract: The present invention relates to novel MDCK cells which can be to grow viruses, e.g., influenza viruses, in cell culture to higher titer than previously possible. The MDCK cells can be adapted to serum-free culture medium. The present invention further relates to cell culture compositions comprising the MDCK cells and cultivation methods for growing the MDCK cells. The present invention further relates to methods for producing influenza viruses in cell culture using the MDCK cells of the invention.

Abstract: Certain examples described herein are directed to optical devices and systems for use in spectroscopy. In particular, certain embodiments described herein are directed to devices and methods that may separate excitation light and Raman optical pathways, prior to sample irradiation, so that, if desired, the excitation light and the Raman scattered radiation may be independently manipulated.

Abstract: The present invention provides novel serum-free cell culture medium and methods for cultivating MDCK cells. In particular, non-tumorigenic MDCK cells. The present invention also provides methods for producing influenza viruses (e.g., particularly cold-adapted, and/or temperature sensitive, and/or attenuated influenza viruses) that eliminate the need for a cell culture medium exchange step. The novel medium and methods are useful to grow influenza viruses, in cell culture to high titer. The present invention further provides purification methods for purifying influenza viruses with high overall recovery of live virus and result in levels of host cell DNA (HCD), host cell protein (HCP) and non-specific endonuclease (e.g., Benzonase), which are below the specifications required by regulatory agencies. The immunogenic compositions can be used to actively immunize subjects or to generate antibodies for a variety of uses, including passive immunization and diagnostic immunoassays.

Abstract: Methods of applying an ozone-depleting catalytic coating to a heat exchanging device for producing a durable surface with optimal ozone depletion characteristics are provided. An adhesively coated metallic substrate is exposed to a concentration of ozone-depleting catalytic particles, wherein the receptive surface of the coated substrate binds the ozone-depleting catalytic coating.

Abstract: Provided are methods, compositions and articles of manufacture for detecting biomarkers indicative of exposure of a mammal to organophosphate compounds. The interaction of such a biomarker with a receptor bound to a biopolymer results in an optical readout that reports the presence of the biomarker.

Abstract: A treated refractory material includes a porous refractory material having one or more protective materials disposed within pores of the refractory material. Methods of preparing the treated refractory material are also provided. The treated refractory material provides protection from the penetration of slag and extends the service life of the refractory material.

Abstract: One method involves the use of stored value account that may be used, for example, to make internet payments, and that can be credited using a variety of payment techniques. Such a method involves receiving money at a money transfer location from a potential purchaser. The money is then stored as an electronic record in a stored value account of the purchaser. This money is then available for transfer at the request of the purchaser. Upon such a request, the money may be electronically sent to a recipient and the stored value account may be debited.

Abstract: A method to prevent chain jump in a drivetrain of a four-wheel drive vehicle including receiving sensed vehicle parameters from sensors in the four-wheel drive vehicle, generating transfer case chain-jump parameters based on the sensed vehicle parameters and sending a command signal to initiate disengagement of a clutch pack in a transfer case of the drivetrain responsive to the generated transfer case chain-jump parameters.