Patents by Inventor Mark Tomishima

Mark Tomishima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF IN VITRO DIFFERENTIATION OF MIDBRAIN DOPAMINE (MDA) NEURONS
    Publication number: 20210123018
    Abstract: The presently disclosed subject matter provides for in vitro methods of inducing differentiation of human stem cells into midbrain dopamine neurons, and precursors thereof, and cells generated by such methods. The presently disclosed subject matter also provides for uses of such cells for treating neurodegenerative disorders.
    Type: Application
    Filed: November 9, 2020
    Publication date: April 29, 2021
    Applicant: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Lorenz Studer, Stefan Irion, Mark Tomishima, Sonja Kriks
  • Methods of in vitro differentiation of midbrain dopamine (MPA) neurons
    Patent number: 10858625
    Abstract: The presently disclosed subject matter provides for in vitro methods of inducing differentiation of human stem cells into midbrain dopamine neurons, and precursors thereof, and cells generated by such methods. The presently disclosed subject matter also provides for uses of such cells for treating neurodegenerative disorders.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: December 8, 2020
    Assignee: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Lorenz Studer, Stefan Irion, Mark Tomishima, Sonja Kriks
  • READY-TO-USE CRYOPRESERVED CELLS
    Publication number: 20200056149
    Abstract: The presently disclosed subject matter relates to compositions of ready-to-use cryopreserved populations of dissociated cells which can be directly used for downstream application without after-thaw expansion and/or passage. The presently disclosed subject matter also provides for methods of preparing such compositions, and in vitro methods of using such compositions.
    Type: Application
    Filed: October 25, 2019
    Publication date: February 20, 2020
    Applicant: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Mark Tomishima, Karen Wong
  • METHODS OF IN VITRO DIFFERENTIATION OF MIDBRAIN DOPAMINE (MDA) NEURONS
    Publication number: 20180094242
    Abstract: The presently disclosed subject matter provides for in vitro methods of inducing differentiation of human stem cells into midbrain dopamine neurons, and precursors thereof, and cells generated by such methods. The presently disclosed subject matter also provides for uses of such cells for treating neurodegenerative disorders.
    Type: Application
    Filed: November 22, 2017
    Publication date: April 5, 2018
    Applicant: MEMORIAL SLOAN-KETTERING CANCER CENTER
    Inventors: Lorenz Studer, Stefan Irion, Mark Tomishima, Sonja Kriks
  • Neural tracing with a conditional herpesvirus and methods and uses thereof
    Publication number: 20030054340
    Abstract: The present invention relates to methods for tracing or characterization of neural circuits or neural connections across synapses. The invention relates to recombinant neurotropic viruses which are useful in tracing or characterizing neural connections across multiple synapses.
    Type: Application
    Filed: March 28, 2002
    Publication date: March 20, 2003
    Inventors: Jeffrey M. Friedman, Jeff DeFalco, Lynn W. Enquist, Mark Tomishima