Abstract: Devices and methods of use for obtaining and maintaining vascular access for the insertion of diagnostic or therapeutic drugs or devices into a patient. A device may include a first conduit extending along a longitudinal axis between a first end and a second end, the first end configured for coupling to a needle and the second end configured for coupling to a syringe. The device also includes a second conduit oblique to the first conduit and in communication with the first conduit. And the device includes a valve in communication with the second conduit, the valve being operatable between a closed position and an open position, wherein the open position is configured to provide access to the second conduit, such that an object may be introduced through the valve and second conduit into the first conduit and out the needle.