Patents by Inventor Mark W. Bleyer

Mark W. Bleyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9456815
    Abstract: An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the graft from the fistula of a patient, the graft may be provided with a cap that extends laterally from at least one end of the body of the graft, where the cap may be integral with the body of the graft, attachable to at least one end of the body of the graft, and/or moveable along the body of the graft. The graft may also have a tail that extends from one end of the body of the graft to assist in placement of the graft in a fistula tract. The graft may be an integral unit made of a single material, such as a heterograft material, or may include distinct components made of the same or different materials. Methods for closing a fistula tract are also provided.
    Type: Grant
    Filed: August 21, 2014
    Date of Patent: October 4, 2016
    Assignees: COOK MEDICAL TECHNOLOGIES LLC, COOK BIOTECH INCORPORATED
    Inventors: David N. Armstrong, Brian L. Bates, Mark W. Bleyer, F. Joseph Obermiller, Umesh H. Patel
  • Publication number: 20160206785
    Abstract: Described are embodiments of a multilaminate or multiple layer implantable surgical graft with an illustrative graft comprising a remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.
    Type: Application
    Filed: March 29, 2016
    Publication date: July 21, 2016
    Inventors: Umesh H. Patel, Jeffrey Miller, Neal E. Fearnot, Mark W. Bleyer
  • Patent number: 9295757
    Abstract: Described are embodiments of a multilaminate or multiple layer implantable surgical graft with an illustrative graft comprising a remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.
    Type: Grant
    Filed: December 10, 2010
    Date of Patent: March 29, 2016
    Assignee: Cook Biotech Incorporated
    Inventors: Umesh H. Patel, Jeffrey Miller, Neal E. Fearnot, Mark W. Bleyer
  • Patent number: 9089626
    Abstract: Disclosed is a medical device (5) and more particularly, an implantable biomaterial. The biomaterial comprises a radiopaque (22) collagenous biomaterial (10).
    Type: Grant
    Filed: April 19, 2010
    Date of Patent: July 28, 2015
    Assignee: Cook Biotech Incorporated
    Inventors: Mark W. Bleyer, Michael C. Hiles, Umesh H. Patel
  • Publication number: 20140364902
    Abstract: An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the graft from the fistula of a patient, the graft may be provided with a cap that extends laterally from at least one end of the body of the graft, where the cap may be integral with the body of the graft, attachable to at least one end of the body of the graft, and/or moveable along the body of the graft. The graft may also have a tail that extends from one end of the body of the graft to assist in placement of the graft in a fistula tract. The graft may be an integral unit made of a single material, such as a heterograft material, or may include distinct components made of the same or different materials. Methods for closing a fistula tract are also provided.
    Type: Application
    Filed: August 21, 2014
    Publication date: December 11, 2014
    Inventors: David N. Armstrong, Brian L. Bates, Mark W. Bleyer, F. Joseph Obermiller, Umesh H. Patel
  • Patent number: 8840917
    Abstract: An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the graft from the fistula of a patient, the graft may be provided with a cap that extends laterally from at least one end of the body of the graft, where the cap may be integral with the body of the graft, attachable to at least one end of the body of the graft, and/or moveable along the body of the graft. The graft may also have a tail that extends from one end of the body of the graft to assist in placement of the graft in a fistula tract. The graft may be an integral unit made of a single material, such as a heterograft material, or may include distinct components made of the same or different materials. Methods for closing a fistula tract are also provided.
    Type: Grant
    Filed: July 15, 2013
    Date of Patent: September 23, 2014
    Assignees: Cook Medical Technologies LLC, Cook Biotech Incorporated
    Inventors: David N. Armstrong, Brian L. Bates, Mark W. Bleyer, F. Joseph Obermiller, Umesh H. Patel
  • Publication number: 20130304119
    Abstract: An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the graft from the fistula of a patient, the graft may be provided with a cap that extends laterally from at least one end of the body of the graft, where the cap may be integral with the body of the graft, attachable to at least one end of the body of the graft, and/or moveable along the body of the graft. The graft may also have a tail that extends from one end of the body of the graft to assist in placement of the graft in a fistula tract. The graft may be an integral unit made of a single material, such as a heterograft material, or may include distinct components made of the same or different materials. Methods for closing a fistula tract are also provided.
    Type: Application
    Filed: July 15, 2013
    Publication date: November 14, 2013
    Inventors: David N. Armstrong, Brian L. Bates, Mark W. Bleyer, F. Joseph Obermiller, Umesh H. Patel
  • Patent number: 8501217
    Abstract: An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the graft from the fistula of a patient, the graft may be provided with a cap that extends laterally from at least one end of the body of the graft, where the cap may be integral with the body of the graft, attachable to at least one end of the body of the graft, and/or moveable along the body of the graft. The graft may also have a tail that extends from one end of the body of the graft to assist in placement of the graft in a fistula tract. The graft may be an integral unit made of a single material, such as a heterograft material, or may include distinct components made of the same or different materials. Methods for closing a fistula tract are also provided.
    Type: Grant
    Filed: February 1, 2011
    Date of Patent: August 6, 2013
    Assignees: Cook Medical Technologies LLC, Cook Biotech Incorporated
    Inventors: David N. Armstrong, Brain L. Bates, Mark W. Bleyer, F. Joseph Obermiller, Umesh H. Patel
  • Patent number: 8439942
    Abstract: A medical device (40) including a collagenous biomaterial (10) for causing embolus and treating an aneurysm. The collagenous biomaterial (10) includes a small intestine submucosa (12) that is configured into various components (16) for causing a vascular occlusion or a packing aneurysm lumen.
    Type: Grant
    Filed: December 3, 2010
    Date of Patent: May 14, 2013
    Assignee: Cook Bioteck Incorporated
    Inventors: Christopher J. Moran, Thomas G. Kozma, Umesh H. Patel, Mark W. Bleyer
  • Patent number: 8049059
    Abstract: A tissue graft product includes at least one collagen layer comprised of submucosa or renal capsule tissue having slits therein to provide a mesh pattern which in turn establishes a graft structure that is highly deformable. The slits and mesh pattern provide for improved characteristics when utilized as a tissue graft and in particular an external wound care. Preferred devices have multiple submucosa, renal capsule or other collagenous extracellular matrix layers, providing a substantial and lasting scaffold for tissue ingrowth during wound treatment.
    Type: Grant
    Filed: October 25, 2002
    Date of Patent: November 1, 2011
    Assignee: Cook Biotech Incorporated
    Inventors: Mark W. Bleyer, Umesh H. Patel
  • Patent number: 8021417
    Abstract: A prosthetic valve for regulating fluid flow through a body vessel is provided. The valve includes an expandable support frame and a valve leaflet, and includes at least one opening that permits a controlled amount of retrograde flow through the valve when the valve is in a closed configuration. A flap disposed adjacent the opening is able to temporarily and substantially close the opening to contribute to the regulation of retrograde flow proceeding through the valve.
    Type: Grant
    Filed: June 16, 2008
    Date of Patent: September 20, 2011
    Assignee: Cook Medical Technologies LLC
    Inventors: Thomas A. Osborne, Brian C. Case, Mark W. Bleyer, Ram H. Paul
  • Publication number: 20110166673
    Abstract: Described are embodiments of a multilaminate or multiple layer implantable surgical graft with an illustrative graft comprising a remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.
    Type: Application
    Filed: December 10, 2010
    Publication date: July 7, 2011
    Inventors: Umesh H. Patel, Jeffrey Miller, Neal E. Fearnot, Mark W. Bleyer
  • Publication number: 20110125289
    Abstract: An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the graft from the fistula of a patient, the graft may be provided with a cap that extends laterally from at least one end of the body of the graft, where the cap may be integral with the body of the graft, attachable to at least one end of the body of the graft, and/or moveable along the body of the graft. The graft may also have a tail that extends from one end of the body of the graft to assist in placement of the graft in a fistula tract. The graft may be an integral unit made of a single material, such as a heterograft material, or may include distinct components made of the same or different materials. Methods for closing a fistula tract are also provided.
    Type: Application
    Filed: February 1, 2011
    Publication date: May 26, 2011
    Applicant: Cook Biotech Incorporated
    Inventors: David N. Armstrong, Brain L. Bates, Mark W. Bleyer, F. Joseph Obermiller, Umesh H. Patel
  • Publication number: 20110077679
    Abstract: A medical device (40) including a collagenous biomaterial (10) for causing embolus and treating an aneurysm. The collagenous biomaterial (10) includes a small intestine submucosa (12) that is configured into various components (16) for causing a vascular occlusion or a packing aneurysm lumen.
    Type: Application
    Filed: December 3, 2010
    Publication date: March 31, 2011
    Inventors: Christopher J. Moran, Thomas G. Kozma, Umesh H. Patel, Mark W. Bleyer
  • Patent number: 7897167
    Abstract: An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the graft from the fistula of a patient, the graft may be provided with a cap that extends laterally from at least one end of the body of the graft, where the cap may be integral with the body of the graft, attachable to at least one end of the body of the graft, and/or moveable along the body of the graft. The graft may also have a tail that extends from one end of the body of the graft to assist in placement of the graft in a fistula tract. The graft may be an integral unit made of a single material, such as a heterograft material, or may include distinct components made of the same or different materials. Methods for closing a fistula tract are also provided.
    Type: Grant
    Filed: June 21, 2006
    Date of Patent: March 1, 2011
    Assignees: Cook Incorporated, Cook Biotech Incorporated
    Inventors: David N. Armstrong, Brian L. Bates, Mark W. Bleyer, F. Joseph Obermiller, Umesh H. Patel
  • Patent number: 7857825
    Abstract: A medical device (40) including a collagenous biomaterial (10) for causing embolus and treating an aneurysm. The collagenous biomaterial (10) includes a small intestine submucosa (12) that is configured into various components (16) for causing a vascular occlusion or a packing aneurysm lumen.
    Type: Grant
    Filed: November 20, 2003
    Date of Patent: December 28, 2010
    Assignee: Cook Biotech Incorporated
    Inventors: Christopher J. Moran, Mark W. Bleyer, Thomas G. Kozma, Umesh H. Patel
  • Publication number: 20100204782
    Abstract: Disclosed is a medical device (5) and more particularly, an implantable biomaterial. The biomaterial comprises a radiopaque (22) collagenous biomaterial (10).
    Type: Application
    Filed: April 19, 2010
    Publication date: August 12, 2010
    Inventors: Mark W. Bleyer, Michael C. Hiles, Umesh H. Patel
  • Patent number: 7713552
    Abstract: Disclosed is a medical device (5) and more particularly, an implantable biomaterial. The biomaterial comprises a radiopaque (22) collagenous biomaterial (10).
    Type: Grant
    Filed: December 19, 2001
    Date of Patent: May 11, 2010
    Assignee: Cook Biotech Incorporated
    Inventors: Mark W. Bleyer, Michael C. Hiles, Umesh H. Patel
  • Publication number: 20080249612
    Abstract: A prosthetic valve for regulating fluid flow through a body vessel is provided. The valve includes an expandable support frame and a valve leaflet, and includes at least one opening that permits a controlled amount of retrograde flow through the valve when the valve is in a closed configuration. A flap disposed adjacent the opening is able to temporarily and substantially close the opening to contribute to the regulation of retrograde flow proceeding through the valve.
    Type: Application
    Filed: June 16, 2008
    Publication date: October 9, 2008
    Applicant: COOK INCORPORATED
    Inventors: THOMAS A. OSBORNE, BRIAN C. CASE, MARK W. BLEYER, RAM H. PAUL
  • Patent number: 7402171
    Abstract: A prosthetic valve for regulating fluid flow through a body vessel is provided. The valve includes an expandable support frame and a valve leaflet, and includes at least one opening that permits a controlled amount of retrograde flow through the valve when the valve is in a closed configuration.
    Type: Grant
    Filed: March 10, 2004
    Date of Patent: July 22, 2008
    Assignee: Cook Incorporated
    Inventors: Thomas A. Osborne, Brian C. Case, Mark W. Bleyer, Ram H. Paul