Patents by Inventor Mark W. Bleyer
Mark W. Bleyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20220296351Abstract: Described are embodiments of a multilaminate or multiple layer implantable surgical graft with an illustrative graft comprising a remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.Type: ApplicationFiled: June 6, 2022Publication date: September 22, 2022Applicant: Cook Biotech IncorporatedInventors: Umesh H. Patel, Jeffrey Miller, Neal E. Fearnot, Mark W. Bleyer
-
Patent number: 11351021Abstract: Described are embodiments of a multilaminate or multiple layer implantable surgical graft with an illustrative graft comprising a remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.Type: GrantFiled: March 29, 2016Date of Patent: June 7, 2022Assignee: Cook Biotech IncorporatedInventors: Umesh H. Patel, Jeffrey Miller, Neal E. Fearnot, Mark W. Bleyer
-
Patent number: 9456815Abstract: An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the graft from the fistula of a patient, the graft may be provided with a cap that extends laterally from at least one end of the body of the graft, where the cap may be integral with the body of the graft, attachable to at least one end of the body of the graft, and/or moveable along the body of the graft. The graft may also have a tail that extends from one end of the body of the graft to assist in placement of the graft in a fistula tract. The graft may be an integral unit made of a single material, such as a heterograft material, or may include distinct components made of the same or different materials. Methods for closing a fistula tract are also provided.Type: GrantFiled: August 21, 2014Date of Patent: October 4, 2016Assignees: COOK MEDICAL TECHNOLOGIES LLC, COOK BIOTECH INCORPORATEDInventors: David N. Armstrong, Brian L. Bates, Mark W. Bleyer, F. Joseph Obermiller, Umesh H. Patel
-
Publication number: 20160206785Abstract: Described are embodiments of a multilaminate or multiple layer implantable surgical graft with an illustrative graft comprising a remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.Type: ApplicationFiled: March 29, 2016Publication date: July 21, 2016Inventors: Umesh H. Patel, Jeffrey Miller, Neal E. Fearnot, Mark W. Bleyer
-
Patent number: 9295757Abstract: Described are embodiments of a multilaminate or multiple layer implantable surgical graft with an illustrative graft comprising a remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.Type: GrantFiled: December 10, 2010Date of Patent: March 29, 2016Assignee: Cook Biotech IncorporatedInventors: Umesh H. Patel, Jeffrey Miller, Neal E. Fearnot, Mark W. Bleyer
-
Patent number: 9089626Abstract: Disclosed is a medical device (5) and more particularly, an implantable biomaterial. The biomaterial comprises a radiopaque (22) collagenous biomaterial (10).Type: GrantFiled: April 19, 2010Date of Patent: July 28, 2015Assignee: Cook Biotech IncorporatedInventors: Mark W. Bleyer, Michael C. Hiles, Umesh H. Patel
-
Publication number: 20140364902Abstract: An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the graft from the fistula of a patient, the graft may be provided with a cap that extends laterally from at least one end of the body of the graft, where the cap may be integral with the body of the graft, attachable to at least one end of the body of the graft, and/or moveable along the body of the graft. The graft may also have a tail that extends from one end of the body of the graft to assist in placement of the graft in a fistula tract. The graft may be an integral unit made of a single material, such as a heterograft material, or may include distinct components made of the same or different materials. Methods for closing a fistula tract are also provided.Type: ApplicationFiled: August 21, 2014Publication date: December 11, 2014Inventors: David N. Armstrong, Brian L. Bates, Mark W. Bleyer, F. Joseph Obermiller, Umesh H. Patel
-
Patent number: 8840917Abstract: An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the graft from the fistula of a patient, the graft may be provided with a cap that extends laterally from at least one end of the body of the graft, where the cap may be integral with the body of the graft, attachable to at least one end of the body of the graft, and/or moveable along the body of the graft. The graft may also have a tail that extends from one end of the body of the graft to assist in placement of the graft in a fistula tract. The graft may be an integral unit made of a single material, such as a heterograft material, or may include distinct components made of the same or different materials. Methods for closing a fistula tract are also provided.Type: GrantFiled: July 15, 2013Date of Patent: September 23, 2014Assignees: Cook Medical Technologies LLC, Cook Biotech IncorporatedInventors: David N. Armstrong, Brian L. Bates, Mark W. Bleyer, F. Joseph Obermiller, Umesh H. Patel
-
Publication number: 20130304119Abstract: An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the graft from the fistula of a patient, the graft may be provided with a cap that extends laterally from at least one end of the body of the graft, where the cap may be integral with the body of the graft, attachable to at least one end of the body of the graft, and/or moveable along the body of the graft. The graft may also have a tail that extends from one end of the body of the graft to assist in placement of the graft in a fistula tract. The graft may be an integral unit made of a single material, such as a heterograft material, or may include distinct components made of the same or different materials. Methods for closing a fistula tract are also provided.Type: ApplicationFiled: July 15, 2013Publication date: November 14, 2013Inventors: David N. Armstrong, Brian L. Bates, Mark W. Bleyer, F. Joseph Obermiller, Umesh H. Patel
-
Patent number: 8501217Abstract: An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the graft from the fistula of a patient, the graft may be provided with a cap that extends laterally from at least one end of the body of the graft, where the cap may be integral with the body of the graft, attachable to at least one end of the body of the graft, and/or moveable along the body of the graft. The graft may also have a tail that extends from one end of the body of the graft to assist in placement of the graft in a fistula tract. The graft may be an integral unit made of a single material, such as a heterograft material, or may include distinct components made of the same or different materials. Methods for closing a fistula tract are also provided.Type: GrantFiled: February 1, 2011Date of Patent: August 6, 2013Assignees: Cook Medical Technologies LLC, Cook Biotech IncorporatedInventors: David N. Armstrong, Brain L. Bates, Mark W. Bleyer, F. Joseph Obermiller, Umesh H. Patel
-
Patent number: 8439942Abstract: A medical device (40) including a collagenous biomaterial (10) for causing embolus and treating an aneurysm. The collagenous biomaterial (10) includes a small intestine submucosa (12) that is configured into various components (16) for causing a vascular occlusion or a packing aneurysm lumen.Type: GrantFiled: December 3, 2010Date of Patent: May 14, 2013Assignee: Cook Bioteck IncorporatedInventors: Christopher J. Moran, Thomas G. Kozma, Umesh H. Patel, Mark W. Bleyer
-
Patent number: 8049059Abstract: A tissue graft product includes at least one collagen layer comprised of submucosa or renal capsule tissue having slits therein to provide a mesh pattern which in turn establishes a graft structure that is highly deformable. The slits and mesh pattern provide for improved characteristics when utilized as a tissue graft and in particular an external wound care. Preferred devices have multiple submucosa, renal capsule or other collagenous extracellular matrix layers, providing a substantial and lasting scaffold for tissue ingrowth during wound treatment.Type: GrantFiled: October 25, 2002Date of Patent: November 1, 2011Assignee: Cook Biotech IncorporatedInventors: Mark W. Bleyer, Umesh H. Patel
-
Patent number: 8021417Abstract: A prosthetic valve for regulating fluid flow through a body vessel is provided. The valve includes an expandable support frame and a valve leaflet, and includes at least one opening that permits a controlled amount of retrograde flow through the valve when the valve is in a closed configuration. A flap disposed adjacent the opening is able to temporarily and substantially close the opening to contribute to the regulation of retrograde flow proceeding through the valve.Type: GrantFiled: June 16, 2008Date of Patent: September 20, 2011Assignee: Cook Medical Technologies LLCInventors: Thomas A. Osborne, Brian C. Case, Mark W. Bleyer, Ram H. Paul
-
Publication number: 20110166673Abstract: Described are embodiments of a multilaminate or multiple layer implantable surgical graft with an illustrative graft comprising a remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.Type: ApplicationFiled: December 10, 2010Publication date: July 7, 2011Inventors: Umesh H. Patel, Jeffrey Miller, Neal E. Fearnot, Mark W. Bleyer
-
Publication number: 20110125289Abstract: An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the graft from the fistula of a patient, the graft may be provided with a cap that extends laterally from at least one end of the body of the graft, where the cap may be integral with the body of the graft, attachable to at least one end of the body of the graft, and/or moveable along the body of the graft. The graft may also have a tail that extends from one end of the body of the graft to assist in placement of the graft in a fistula tract. The graft may be an integral unit made of a single material, such as a heterograft material, or may include distinct components made of the same or different materials. Methods for closing a fistula tract are also provided.Type: ApplicationFiled: February 1, 2011Publication date: May 26, 2011Applicant: Cook Biotech IncorporatedInventors: David N. Armstrong, Brain L. Bates, Mark W. Bleyer, F. Joseph Obermiller, Umesh H. Patel
-
Publication number: 20110077679Abstract: A medical device (40) including a collagenous biomaterial (10) for causing embolus and treating an aneurysm. The collagenous biomaterial (10) includes a small intestine submucosa (12) that is configured into various components (16) for causing a vascular occlusion or a packing aneurysm lumen.Type: ApplicationFiled: December 3, 2010Publication date: March 31, 2011Inventors: Christopher J. Moran, Thomas G. Kozma, Umesh H. Patel, Mark W. Bleyer
-
Patent number: 7897167Abstract: An implantable graft, which may be inserted into a fistula tract to occlude the primary opening of the fistula, is provided. To prevent unintentional displacement of the graft or extrusion of the graft from the fistula of a patient, the graft may be provided with a cap that extends laterally from at least one end of the body of the graft, where the cap may be integral with the body of the graft, attachable to at least one end of the body of the graft, and/or moveable along the body of the graft. The graft may also have a tail that extends from one end of the body of the graft to assist in placement of the graft in a fistula tract. The graft may be an integral unit made of a single material, such as a heterograft material, or may include distinct components made of the same or different materials. Methods for closing a fistula tract are also provided.Type: GrantFiled: June 21, 2006Date of Patent: March 1, 2011Assignees: Cook Incorporated, Cook Biotech IncorporatedInventors: David N. Armstrong, Brian L. Bates, Mark W. Bleyer, F. Joseph Obermiller, Umesh H. Patel
-
Patent number: 7857825Abstract: A medical device (40) including a collagenous biomaterial (10) for causing embolus and treating an aneurysm. The collagenous biomaterial (10) includes a small intestine submucosa (12) that is configured into various components (16) for causing a vascular occlusion or a packing aneurysm lumen.Type: GrantFiled: November 20, 2003Date of Patent: December 28, 2010Assignee: Cook Biotech IncorporatedInventors: Christopher J. Moran, Mark W. Bleyer, Thomas G. Kozma, Umesh H. Patel
-
Publication number: 20100204782Abstract: Disclosed is a medical device (5) and more particularly, an implantable biomaterial. The biomaterial comprises a radiopaque (22) collagenous biomaterial (10).Type: ApplicationFiled: April 19, 2010Publication date: August 12, 2010Inventors: Mark W. Bleyer, Michael C. Hiles, Umesh H. Patel
-
Patent number: 7713552Abstract: Disclosed is a medical device (5) and more particularly, an implantable biomaterial. The biomaterial comprises a radiopaque (22) collagenous biomaterial (10).Type: GrantFiled: December 19, 2001Date of Patent: May 11, 2010Assignee: Cook Biotech IncorporatedInventors: Mark W. Bleyer, Michael C. Hiles, Umesh H. Patel