Patents by Inventor Mark W. Dudley

Mark W. Dudley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Serotonin antagonists
    Publication number: 20040176413
    Abstract: The present invention is directed to a new class of serotonin 5HT2 antagonists and thier use in the treatment of a variety of diseases.
    Type: Application
    Filed: March 16, 2004
    Publication date: September 9, 2004
    Applicant: Aventis Pharmaceuticals Inc.
    Inventors: Thaddeus R. Nieduzak, Mark W. Dudley, John H. Kehne
  • Serotonin antagonists
    Publication number: 20030212141
    Abstract: The present invention is directed to a new class of serotonin 5HT2 antagonists and thier use in the treatment of a variety of diseases.
    Type: Application
    Filed: April 9, 2003
    Publication date: November 13, 2003
    Inventors: Thaddeus R. Nieduzak, Mark W. Dudley, John H. Kehne
  • Serotonin antagonists
    Publication number: 20030083325
    Abstract: The present invention is directed to a new class of serotonin 5HT2 antagonists and thier use in the treatment of a variety of diseases.
    Type: Application
    Filed: June 21, 2002
    Publication date: May 1, 2003
    Inventors: Thaddeus R. Nieduzak, Mark W. Dudley, John H. Kehne
  • Serotonin antagonists
    Publication number: 20020002174
    Abstract: The present invention is directed to a new class of serotonin 5HT2 antagonists and thier use in the treatment of a variety of diseases.
    Type: Application
    Filed: May 19, 2000
    Publication date: January 3, 2002
    Inventors: Thaddeus R. Nieduzak, John H. Kehne, Mark W. Dudley
  • Antidepressants
    Patent number: 6136803
    Abstract: The present invention provides novel compounds such as certain aryloxy indanamines which are useful as anti-depressants and as inhibitors of synaptic norepinephrine and serotonin uptake. The present invention also provides an improvement in the treatment of depression which comprises inhibiting synaptic serotonin and epinepherine uptake.
    Type: Grant
    Filed: December 10, 1998
    Date of Patent: October 24, 2000
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Jules Freedman, Mark W. Dudley
  • Treating depression by administering an antidepressant
    Patent number: 5880120
    Abstract: The present invention provides novel compounds such as certain aryloxy indanamines which are useful as anti-depressants and as inhibitors of synaptic norepinephrine and serotonin uptake. The present invention also provides an improvement in the treatment of depression which comprises inhibiting synaptic serotonin and epinepherine uptake.
    Type: Grant
    Filed: September 11, 1997
    Date of Patent: March 9, 1999
    Assignee: Merrell Pharmaceuticals, Inc.
    Inventor: Mark W. Dudley
  • Xanthine derivatives as adenosine A1 receptor antagonists
    Patent number: 5840729
    Abstract: A method of attenuating a cognitive deficit in a patient in need thereof comprising administering to the patient a xanthine derivative.
    Type: Grant
    Filed: December 18, 1995
    Date of Patent: November 24, 1998
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Janice M. Hitchcock, Stephen M. Sorensen, Mark W. Dudley, Norton P. Peet
  • Piperidinyl thiacyclic derivatives
    Patent number: 5739150
    Abstract: Piperidinyl thiacyclic derivatives useful in the treatment of allergic diseases and diseases responding to antagonism of 5HT.sub.2 receptors, pharmaceutical compositions and a methods of treatment using these compounds.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: April 14, 1998
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Albert A. Carr, John M. Kane, George D. Maynard, Hsien C. Cheng, Mark W. Dudley
  • Piperidinyl thiacyclic derivatives
    Patent number: 5650416
    Abstract: Piperidinyl thiacyclic derivatives of the formula ##STR1## wherein X, Y, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are defined in the specification, are useful in the treatment of allergic diseases and diseases responding to antagonism of 5HT.sub.2 receptors. Pharmaceutical compositions and methods of treatment using these compounds are also disclosed.
    Type: Grant
    Filed: May 24, 1995
    Date of Patent: July 22, 1997
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Albert A. Carr, John M. Kane, George D. Maynard, Hsien C. Cheng, Mark W. Dudley
  • Piperidinyl thiacyclic derivatives
    Patent number: 5631268
    Abstract: Piperidinyl thiacyclic derivatives of the formula ##STR1## wherein X, Y, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are defined in the specification, are useful in the treatment of allergic diseases and diseases responding to antagonism of 5HT.sub.2 receptors. Pharmaceutical compositions and methods of treatment using these compounds are also disclosed.
    Type: Grant
    Filed: May 24, 1995
    Date of Patent: May 20, 1997
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Albert A. Carr, John M. Kane, George D. Maynard, Hsien C. Cheng, Mark W. Dudley
  • Piperidinyl thiacyclic derivatives
    Patent number: 5602147
    Abstract: Piperidinyl thiacyclic derivatives useful in the treatment of allergic diseases and diseases responding to antagonism of 5HT.sub.2 receptors, pharmaceutical compositions and a methods of treatment using these compounds.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: February 11, 1997
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Albert A. Carr, John M. Kane, George D. Maynard, Hsien C. Cheng, Mark W. Dudley
  • Piperidinyl thiacyclic derivatives
    Patent number: 5596003
    Abstract: Piperidinyl thiacyclic derivatives useful in the treatment of allergic diseases and diseases responding to antagonism of 5HT.sub.2 receptors, pharmaceutical compositions and a methods of treatment using these compounds.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: January 21, 1997
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Albert A. Carr, John M. Kane, George D. Maynard, Hsien C. Cheng, Mark W. Dudley
  • Serotonin 5HT.sub.1A agonistic method
    Patent number: 5559143
    Abstract: The present invention is directed to a new class of serotonin 5HT.sub.1A agonists.
    Type: Grant
    Filed: October 7, 1994
    Date of Patent: September 24, 1996
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Ian A. McDonald, Ronald C. Bernotas, Mark W. Dudley, Jeffrey S. Sprouse
  • Piperidinyl thiacyclic derivatives
    Patent number: 5541200
    Abstract: Piperidinyl thiacyclic derivatives ##STR1## wherein X, Y, R.sub.1, R.sub.2, R.sub.3, and R.sub.4 are defined in the specification. useful in the treatment of allergic diseases and diseases responding to antagonism of 5HT.sub.2 receptors, pharmaceutical compositions and a methods of treatment using these compounds.
    Type: Grant
    Filed: May 24, 1995
    Date of Patent: July 30, 1996
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Albert A. Carr, John M. Kane, George D. Maynard, Hsien C. Cheng, Mark W. Dudley
  • Method of treating drug abuse
    Patent number: 5500433
    Abstract: The present invention is directed to a new class of piperidinyl medicinal agents which are useful for treating drug abuse.
    Type: Grant
    Filed: January 10, 1995
    Date of Patent: March 19, 1996
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Albert A. Carr, Richard C. Dage, John E. Koerner, Tung Li, Francis P. Miller, Thaddeus R. Nieduzak, Mark W. Dudley, . Christopher J. Schmidt, Robert A. Frank
  • Piperidinyl thiacyclic derivatives
    Patent number: 5476861
    Abstract: Piperidinyl thiacyclic derivatives of the formula ##STR1## wherein X, Y, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are defined in the specification, are useful in the treatment of allergic diseases and diseases responding to antagonism of 5HT.sub.2 receptors. Pharmaceutical compositions and methods of treatment using these compounds are also disclosed.
    Type: Grant
    Filed: July 28, 1994
    Date of Patent: December 19, 1995
    Assignee: Merrell Dow Pharmaceuricals Inc.
    Inventors: Albert A. Carr, John M. Kane, George D. Maynard, Hsien C. Cheng, Mark W. Dudley
  • Arylalkoxyphenoxy-imidazoline compounds
    Patent number: 5407954
    Abstract: The present invention is directed to a new class of arylalkoxyphenoxy-imidazoline compounds and their use for the treatment of depression, anxiety, hypertension, and migraine headaches.
    Type: Grant
    Filed: February 9, 1994
    Date of Patent: April 18, 1995
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Jules Freedman, Bruce M. Baron, Mark W. Dudley
  • 1,4 benzodioxin derivatives and their use as serotonin 5HT.sub.1A agonists
    Patent number: 5387604
    Abstract: The present invention is directed to a new class of serotonin 5HT.sub.1A agonists.
    Type: Grant
    Filed: October 16, 1992
    Date of Patent: February 7, 1995
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Ian A. McDonald, Ronald C. Bernotas, Mark W. Dudley, Jeffrey S. Sprouse
  • Piperidinyl thiacyclic derivatives
    Patent number: 5371093
    Abstract: Piperidinyl thiacyclic derivatives ##STR1## wherein X, Y, R.sub.1, R.sub.2, R.sub.3, and R.sub.4 are defined in the specification. useful in the treatment of allergic diseases and diseases responding to antagonism of 5HT.sub.2 receptors, pharmaceutical compositions and a methods of treatment using these compounds.
    Type: Grant
    Filed: February 24, 1994
    Date of Patent: December 6, 1994
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Albert A. Carr, George D. Maynard, John M. Kane, Hsien C. Cheng, Mark W. Dudley
  • Arylalkoxyphenoxy-imidazoline compounds
    Patent number: 5216008
    Abstract: The present invention is directed to a new class of arylalkoxyphenoxy-imidazoline compounds and their use for the treatment of depression, anxiety, hypertension, and migraine headaches.
    Type: Grant
    Filed: February 6, 1992
    Date of Patent: June 1, 1993
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Jules Freedman, Bruce M. Baron, Mark W. Dudley