Patents by Inventor Mark Wallet

Mark Wallet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
    Patent number: 12269888
    Abstract: Provided are polynucleotides encoding inactivated cell surface receptors. Also provided are genetically engineered induced pluripotent stem cells (iPSCs) and derivative cells thereof expressing a chimeric antigen receptor (CAR) and methods of using the same. Also provided are compositions, polypeptides, vectors, and methods of manufacturing.
    Type: Grant
    Filed: March 30, 2023
    Date of Patent: April 8, 2025
    Assignee: Century Therapeutics, Inc.
    Inventors: Michael Naso, Jill Carton, John Wheeler, Luis Borges, Mark Wallet, Barry Morse, Hillary Quinn, Liam Campion, Buddha Gurung, Heidi Jessup, Kenneth Brasel, Lucas Thompson
  • GENETICALLY ENGINEERED CELLS HAVING ANTI-CD19 / ANTI-CD22 CHIMERIC ANTIGEN RECEPTORS, AND USES THEREOF
    Publication number: 20250064934
    Abstract: Provided are genetically engineered induced pluripotent stem cells (iPSCs) and derivative cells thereof expressing a chimeric antigen receptor (CAR) and methods of using the same. Also provided are compositions, polypeptides, vectors, and methods of manufacturing.
    Type: Application
    Filed: December 27, 2022
    Publication date: February 27, 2025
    Inventors: Jill Marinari CARTON, John WHEELER, Christopher DOWER, Raisa UCHUROVA, Michael MILLER, Toshinobu NISHIMURA, Katherine SANTOSTEFANO, Mark WALLET
  • Compositions and Methods for Generating Gamma-Delta T Cells from Induced Pluripotent Stem Cells
    Publication number: 20250066728
    Abstract: Provided are methods for generating ?? T cells from induced pluripotent stem cells. Also provided are genetically engineered iPSCs, ?? T cells, CAR-?? T cells, and methods of using the same.
    Type: Application
    Filed: September 16, 2024
    Publication date: February 27, 2025
    Inventors: Mark Wallet, Toshinobu Nishimura, Mark Mendonca, Andriana Lebid, Brenda Salantes, Katherine Santostefano, Michael Francis Naso, Buddha Gurung, Zengrong Zhu, Barry Morse, Luis Borges, Christina Del Casale, Marilda Beqiri, Lucas Thompson
  • ARTIFICIAL CELL DEATH POLYPEPTIDE FOR CHIMERIC ANTIGEN RECEPTOR AND USES THEREOF
    Publication number: 20250059286
    Abstract: Provided are polynucleotides encoding inactivated cell surface receptors. Also provided are genetically engineered induced pluripotent stem cells (iPSCs) and derivative cells thereof expressing a chimeric antigen receptor (CAR) and methods of using the same. Also provided are compositions, polypeptides, vectors, and methods of manufacturing.
    Type: Application
    Filed: November 4, 2024
    Publication date: February 20, 2025
    Inventors: Michael Naso, Jill Carton, Mark Wallet, Barry Morse, Luis Borges, Buddha Gurung, Hillary Quinn, Liam Campion, Heidi Jessup, Kenneth Brasel, Lucas Thompson, John Wheeler
  • Compositions and Methods for Generating Gamma-Delta T Cells from Induced Pluripotent Stem Cells
    Publication number: 20220333073
    Abstract: Provided are methods for generating ?? T cells from induced pluripotent stem cells. Also provided are genetically engineered iPSCs, ?? T cells, CAR-?? T cells, and methods of using the same.
    Type: Application
    Filed: April 4, 2022
    Publication date: October 20, 2022
    Inventors: Mark Wallet, Toshinobu Nishimura, Mark Mendonca, Andriana Lebid, Brenda Salantes, Katherine Santostefano, Michael Francis Naso, Buddha Gurung, Zengrong Zhu, Barry Morse, Luis Borges, Christina Del Casale, Marilda Beqiri, Lucas Thompson
  • Compositions and Methods for Generating Alpha-Beta T Cells from Induced Pluripotent Stem Cells
    Publication number: 20220333074
    Abstract: Provided are method for generating ?? T cells from induced pluripotent stem cells. Also provided are genetically engineered iPSCs, ?? T cells, CAR-?? T cells, and methods of using the same.
    Type: Application
    Filed: April 4, 2022
    Publication date: October 20, 2022
    Inventors: Mark Wallet, Katherine Santostefano, Brenda Salantes, Mark Mendonca, Toshinobu Nishimura, Michael Francis Naso, Buddha Gurung, Zengrong Zhu, Barry Morse, Luis Borges, Jill Marinari Carton
  • Genetically Engineered Cells and Uses Thereof
    Publication number: 20220195396
    Abstract: Provided are genetically engineered induced pluripotent stem cells (iPSCs) and derivative cells thereof expressing a chimeric antigen receptor (CAR) and methods of using the same. Also provided are compositions, polypeptides, vectors, and methods of manufacturing.
    Type: Application
    Filed: December 1, 2021
    Publication date: June 23, 2022
    Inventors: Michael Naso, Jill Carton, Mark Wallet, Barry Morse, Luis Borges, Buddha Gurung, Hillary Quinn, Liam Campion, Heidi Jessup, Kenneth Brasel, Lucas Thompson
  • Genetically Engineered Cells and Uses Thereof
    Publication number: 20220184123
    Abstract: Provided are genetically engineered induced pluripotent stem cells (iPSCs) and derivative cells thereof expressing a chimeric antigen receptor (CAR) and methods of using the same. Also provided are compositions, polypeptides, vectors, and methods of manufacturing.
    Type: Application
    Filed: December 1, 2021
    Publication date: June 16, 2022
    Inventors: Michael Naso, Jill Carton, Mark Wallet, Barry Morse, Luis Borges, Hillary Quinn, Liam Campion, Buddha Gurung, Heidi Jessup, Kenneth Brasel, Lucas Thompson