Abstract: A method and semi-permanent system for applying various pesticides within an interior space of a building structure includes a pipeline having a plurality of solenoid valves, each valve controlled by a microcontroller so that a predetermined amount of pesticide is distributed according to a predetermined, sequential timed firing sequence. The pipeline is installed external to an interior wall surface and may extend to areas far removed from the wall. A second pipeline supplies air to the solenoid valves and the microcontroller controls the flow of air to the valves so that an effective wet spray-cold aerosol fogging may be achieved. One or more sensors may be used to monitor the interior space of the building for purposes of safety. The entire system may be controlled through a computer interface, a network interface controller, a web-based interface, or a wireless device interface.