Abstract: A lift device includes a hydraulic actuator configured to move an implement relative to a chassis, an implement circuit including a first pump coupled to the hydraulic actuator, a charge circuit including a second pump configured to selectively provide a flow of pressurized fluid to the implement circuit, a valve assembly fluidly coupled to the implement circuit and the charge circuit, and processing circuitry. The processing circuitry is configured to: in a first mode of operation, control the valve assembly to direct the flow of pressurized fluid to the charge circuit; in a second mode of operation, control the valve assembly to divert the flow of pressurized fluid to the implement circuit; and reconfigure the lift device between the first mode of operation and the second mode of operation in response to a command for the hydraulic actuator to at least one of move or reconfigure the implement.

Abstract: A vehicle includes a hydraulic actuator configured to move an implement relative to the chassis, a hydraulic motor configured to propel the vehicle, a drive pump fluidly coupled to the hydraulic motor, a charge pump configured to provide a flow of pressurized fluid, and a valve assembly fluidly coupled to the charge pump. The valve assembly is configured to (a) direct a first portion of the flow of pressurized fluid to the drive pump, the first portion of the flow having a first flow rate and (b) direct a second portion of the flow of pressurized fluid to the hydraulic actuator, the second portion of the flow having a second flow rate. The valve assembly includes a valve element that is configured to vary at least one of the first flow rate or the second flow rate based on a pressure at a position upstream of the valve element.

Abstract: Disclosed herein are several embodiments of a negative pressure appliance and methods of using the same in the treatment of wounds. Some embodiments are directed to improved fluidic connectors or suction adapters for connecting to a wound site, for example using softer, kink-free conformable suction adapters.

Abstract: Apparatuses, systems, and methods to move end connectors. In at least one embodiment, a linkage system to move an end connector between at least a first position and a second position is driven by an actuator in a first direction to drive movement of the end connector in a second direction, perpendicular to the first direction.

Abstract: Anti-PVRIG and anti-TIGIT antibodies are provided.

Abstract: The present invention is directed to anti-PVRIG antibodies and methods of using same.

Abstract: The present invention is directed to anti-PVRIG antibodies and stable liquid pharmaceutical formulations thereof. The present invention is directed to monotherapy and combination treatments with anti-PVRIG antibodies and anti-PD-1 antibodies, in particular nivolumab, using stable liquid pharmaceutical formulations thereof.

Abstract: Anti-PVRIG and anti-TIGIT antibodies are provided.

Abstract: A data processing system is configured to pre-process data for a machine learning classifier. The data processing system includes an input port that receives one or more data items, an extraction engine that extracts a plurality of data signatures and structure data, a logical rule set generation engine configured to generate a data structure, select a particular data signature of the data structure, identify each instance of the particular data signature in the data structure, segment the data structure around instances of the particular data signature, identify one or more sequences of data signatures connected to the particular data signature, and generate a logical ruleset. A classification engine executes one or more classifiers against the logical ruleset to classify the one or more data items received by the input port.

Abstract: The present invention is directed to PVRIG polypeptides and their uses.

Abstract: A vehicle includes a hydraulic actuator configured to move an implement relative to the chassis, a hydraulic motor configured to propel the vehicle, a drive pump fluidly coupled to the hydraulic motor, a charge pump configured to provide a flow of pressurized fluid, and a valve assembly fluidly coupled to the charge pump. The valve assembly is configured to (a) direct a first portion of the flow of pressurized fluid to the drive pump, the first portion of the flow having a first flow rate and (b) direct a second portion of the flow of pressurized fluid to the hydraulic actuator, the second portion of the flow having a second flow rate. The valve assembly includes a valve element that is configured to vary at least one of the first flow rate or the second flow rate based on a pressure at a position upstream of the valve element.

Abstract: The present invention is directed to PVRIG polypeptides and their uses.

Abstract: The present invention is directed to anti-PVRIG antibodies and methods of using same.

Abstract: A vehicle includes a chassis, an implement coupled to the chassis, a hydraulic actuator configured to move the implement relative to the chassis, a tractive element coupled to the chassis, a hydraulic motor configured to drive the tractive element to propel the vehicle, a drive pump fluidly coupled to the hydraulic motor, a charge pump coupled to the chassis and configured to provide a flow of pressurized fluid, and a valve assembly fluidly coupled to the charge pump. The valve assembly is configured to (a) direct a first portion of the flow of pressurized fluid to the drive pump and (b) selectively direct a second portion of the flow of pressurized fluid to the hydraulic actuator.

Abstract: Methods, systems, and computer-readable media for sizing a population of nucleic acid fragments. In an exemplary method of sizing a population of nucleic acid fragments provided by a sample, partitions may be formed, each containing a portion of the sample. Each target of at least two targets may be present in only a fraction of the nucleic acid fragments. Amplification reactions may be performed for each of the at least two targets in the partitions. Amplification data may be collected for the at least two targets from the partitions. Target-defined subsets of the partitions may be enumerated using the amplification data. At least one length characteristic of the population of nucleic acid fragments may be predicted using results of enumerating.

Abstract: Anti-PVRIG and anti-TIGIT antibodies are provided.

Abstract: Disclosed herein are several embodiments of a negative pressure appliance and methods of using the same in the treatment of wounds. Some embodiments are directed to improved fluidic connectors or suction adapters for connecting to a wound site, for example using softer, kink-free conformable suction adapters.

Abstract: Apparatuses, systems, and methods to move end connectors. In at least one embodiment, a linkage system to move an end connector between at least a first position and a second position is driven by an actuator in a first direction to drive movement of the end connector in a second direction, perpendicular to the first direction.