Abstract: Embodiments are disclosed for estimating time outdoors and in daylight based on ambient light, motion, and location sensing. In some embodiments, a method comprises detecting daylight based on an ambient light measurement, an estimated sun elevation angle and at least one confidence threshold; determining a motion or activity state of a user based on motion sensor data; determining an indoor or outdoor class based on the motion sensor data and the ambient light detections; determining user exposure time to daylight between, before or after ambient light detections, based on the motion or activity state, and the determined indoor or outdoor class; and storing or displaying the daylight time.

Abstract: A non-fungible management system may generate non-fungible tokens based on credential data of a user. In one example, a non-fungible token can be generated responsive to receiving credential data for the user, whereby the credential data is received from a verified credentialing organization. Non-fungible tokens based on credential data can be held in a digital wallet of the user, used as a resume or record of achievement, and/or traded in a marketplace.

Abstract: A health data management method using non-fungible tokens may include receiving, via one processor, digital health data and encrypting or obscuring personal identifying information of the digital health data. The method may then involve using the digital health data with encrypted or obscured personal identifying information to generate a non-fungible token and providing the non-fungible tokens in a marketplace. The method may also involve accepting an offer from a purchaser for the non-fungible token via the marketplace and providing unobscured digital health data or an encryption key to the purchaser of the non-fungible token.

Abstract: In an embodiment, an electrolyte includes a lithium salt and a cosolvent, where the cosolvent comprises a cyclic carbonate-containing solvent and a linear carbonate-containing solvent. In an embodiment, a battery includes an anode, a cathode, an electrolyte and a separator. The anode includes an anode current collector and an anode active layer. The anode active layer comprises a lithiated silicon oxide or a combination of lithiated silicon oxide and carbon present in an amount of 20 wt % or greater, based on a total weight of the anode active layer. The cathode includes a cathode current collector and a cathode active layer. The electrolyte includes a lithium salt and a cosolvent that includes a cyclic carbonate-containing solvent and a linear carbonate-containing solvent.

Abstract: Aspects of the disclosure include systems and methods for manufacturing thermally stable nickel-rich cathodes. An exemplary method can include providing an active material including a plurality of active material particles. The plurality of active material particles include nickel. A nanoparticle slurry additive having a plurality of nanoparticles is provided. The plurality of nanoparticles include one or more of a thermally stable olivine type material, a thermally stable spinel type material, and a thermally stable manganese-nickel dioxide type material. The method includes forming a slurry by mixing the active material and the nanoparticle slurry additive. The plurality of nanoparticles form a thermal inhibitor layer on and in direct contact with a surface of the plurality of active material particles. A free-standing electrode film is formed by calendering the slurry and the free-standing electrode film is laminating to a current collector to define a thermally stable nickel-rich cathode.

Abstract: Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are inhibitors of Nav1.8 channel activity and may be useful in the treatment, prevention, management, amelioration, control and suppression of diseases mediated by Nav1.8 channel activity. The compounds of the present invention may be useful in the treatment, prevention or management of pain disorders, cough disorders, acute itch disorders, and chronic itch disorders.

Abstract: Systems and methods for searching data management systems. Administrative users may define rules for hashtags, and then the rules are dynamically applied on the fly when an end user searches customer data. Hashtags are used to filter records for specific data, so as to improve data search accuracy and efficiency.

Abstract: The present invention relates to anti-VP1 antibodies, antibody fragments, and their uses for the prevention and treatment of polyoma virus infection and associated diseases.

Abstract: An apparatus for a microprocessor computer system and method for configuring the same where said microprocessor computer system comprises a processor core and at least one hardware buffer FIFO with memory-mapped head and tail that handles data movement among the processor cores, networks, raw data input and outputs, and memory. The method for configuring said microprocessor computer system comprises utilizing a FIFO auxiliary processor to process said data traversing said hardware FIFO; utilizing said hardware FIFOs to efficiently pipe data through functional blocks; and utilizing a FIFO controller to perform DMA operations that include non-unit-stride access patterns and transfers among processor cores, networks, raw data input and outputs, memory, and other memory-mapped hardware FIFOs.

Abstract: Disclosed herein are system, method, and computer program product embodiments for asset-invoked reaction indication. According to some aspects of this disclosure, a first device may request to send an asset to a second device. A response action for the asset may be identified based on a user profile associated with the second device and a type of the asset. The asset may be sent to the second device responsive to identifying the response action. The response action may be triggered based on an indication that the second device received the asset.

Abstract: A profile or article formed from a moisture- and/or thermo-curable elastomeric polymer composition including: (A) at least one ethylene-olefinic monomer-silane polymer; wherein the polymer has an olefinic monomer content of from 5 weight percent to 50 weight percent and a silane content of from 0.1 weight percent to 2.5 weight percent; and wherein the polymer has a melt index of from 0.1 gram/10 minutes to 10.0 grams/10; and (B) at least one silanol condensation catalyst; a shaped article made from the above elastomeric polymer composition; and a method of making a shaped article using the above elastomeric polymer composition.

Abstract: Devices are presented for measurement of an analyte concentration. The devices comprise: a sensor configured to generate a signal indicative of a concentration of an analyte; and a sensing membrane located over the sensor. The sensing membrane comprises an enzyme domain comprising an enzyme, a base polymer, and a hydrophilic polymer which makes up from about 5 wt. % to about 30 wt. % of the enzyme domain.

Abstract: Devices are presented for measurement of an analyte concentration. The devices comprise: a sensor configured to generate a signal indicative of a concentration of an analyte; and a sensing membrane located over the sensor. The sensing membrane comprises an enzyme domain comprising an enzyme, a base polymer, and a hydrophilic polymer which makes up from about 5 wt. % to about 30 wt. % of the enzyme domain.

Abstract: A method of monitoring compliance with an insulin regimen prescribed for a diabetic patient includes receiving continuous glucose monitoring (CGM) data for the patient over a period of time; determining a degree of variability in the CGM data obtained over the period of time; evaluating compliance with the prescribed insulin regimen based at least in part on the degree of variability in the CGM data that is determined; and responsive to the evaluating, causing at least one action to be performed to facilitate a change in patient behavior that increases compliance with the prescribed insulin regimen when compliance is determined to be less than required to optimize therapeutic treatment of diabetes in the diabetic patient.

Abstract: A working wire for a continuous biological sensor is disclosed and includes a substrate having a conductive surface and an enzyme layer formed on the conductive surface. The enzyme layer includes enzymes, an immobilization matrix and a polymeric crosslinking agent that crosslinks the enzymes and the immobilization matrix creating an enzyme immobilization network. A protective layer is included over the enzyme layer. A method for making the working wire for a continuous biological sensor is disclosed and includes combining an enzyme with a solvent creating an enzyme mixture. An immobilization matrix is mixed with the enzyme mixture. After the mixing, a polymeric crosslinking agent is combined with the enzyme mixture and the immobilization matrix creating a crosslinked mixture. The crosslinked mixture is allowed to stabilize. The stabilized crosslinked mixture is applied to the working wire, and the applied mixture is cured on the working wire.

Abstract: A glucose-specific sensor has a glucose limiting layer (GLL), an enzyme layer and an interference layer. The GLL comprises polyurethane with a molecular weight greater than 100,000 Daltons that is physically crosslinked with a water-soluble polymer having a molecular weight greater than 100,000 Daltons. The interference layer has a polymer formed from pyrrole, phenylenediamine (PDA), aminophenol, aniline, or combinations thereof. Methods for making a glucose-specific sensor include mixing a monomer with a solvent to form a monomer solution, applying the monomer solution to a substrate and electropolymerizing the monomer to form a polymer on the substrate. The polymer is an interference layer for the glucose-specific sensor. An enzyme layer is formed on the interference layer, and a glucose limiting layer is formed on the enzyme layer.

Abstract: Provided are systems and methods using which users may learn and become familiar with the effects of various aspects of their lifestyle on their health, e.g., users may learn about how food and/or exercise affects their glucose level and other physiological parameters, as well as overall health. In some cases the user selects a program to try; in other cases, a computing environment embodying the system suggests programs to try, including on the basis of pattern recognition, i.e., by the computing environment determining how a user could improve a detected pattern in some way. In this way, users such as type II diabetics or even users who are only prediabetic or non-diabetic may learn healthy habits to benefit their health.

Abstract: A metabolic analyte sensor includes a substrate having an electrically conductive surface, an interference layer on the conductive surface, an enzyme layer on the interference layer, and a glucose limiting layer on the enzyme layer. The interference layer or the enzyme layer is configured such that the metabolic analyte sensor has an improved performance characteristic after sterilization compared to before sterilization. A packaged continuous metabolic monitor includes a sealed container; a metabolic sensor in the sealed container for insertion into a patient after the metabolic sensor is removed from the sealed container, the metabolic sensor comprising a conductive surface and an enzyme layer; electronic operating circuitry in the sealed container and coupled to the metabolic sensor; and a residue of a sterilizing gas in the metabolic sensor. The sealed container, the metabolic sensor and the electronic operating circuitry are sterilized together in the sealed container using the sterilizing gas.

Abstract: Provided are systems and methods using which users may learn and become familiar with the effects of various aspects of their lifestyle on their health, e.g., users may learn about how food and/or exercise affects their glucose level and other physiological parameters, as well as overall health. In some cases the user selects a program to try; in other cases, a computing environment embodying the system suggests programs to try, including on the basis of pattern recognition, i.e., by the computing environment determining how a user could improve a detected pattern in some way. In this way, users such as type II diabetics or even users who are only prediabetic or non-diabetic may learn healthy habits to benefit their health.

Abstract: Devices are presented for measurement of an analyte concentration. The devices comprise: a sensor configured to generate a signal indicative of a concentration of an analyte; and a sensing membrane located over the sensor. The sensing membrane comprises an enzyme domain comprising an enzyme, a base polymer, and a hydrophilic polymer which makes up from about 5 wt. % to about 30 wt. % of the enzyme domain.