Patents by Inventor Mark Yarchoan

Mark Yarchoan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FUSION PROTEINS AND METHODS OF USE THEREOF
    Publication number: 20230173049
    Abstract: The invention features compositions and methods for treating and preventing cancer. In one aspect, isolated fusion proteins are provided that comprise a DNAJBI portion and a PRKACA portion. In a further aspect, compositions are provided, including immunogenic compositions that comprise an isolated fusion protein comprising a DNAJBI portion and a PRKACA portion. In a yet further aspect, a cancer vaccine is provided that comprises an isolated fusion protein comprising a DNAJBI portion and a PRKACA portion.
    Type: Application
    Filed: December 31, 2020
    Publication date: June 8, 2023
    Inventors: Mark Yarchoan, Elizabeth Jaffee, Aditya Mohan
  • BAFF THERAPY TO PROMOTE ANTI-TUMOR IMMUNITY
    Publication number: 20220133788
    Abstract: Anti-tumor immune response are generated by induction of activated B cells to provide costimulatory signals necessary for T cell activation. Certain compositions are combined with anti-immune checkpoint inhibitors to generate a synergistic anti-tumor response.
    Type: Application
    Filed: December 19, 2018
    Publication date: May 5, 2022
    Inventors: Elizabeth A. Jaffee, Mark Yarchoan
  • Compositions and methods for treating cognitive deficits
    Patent number: 9682125
    Abstract: A method of treating or preventing cognitive impairment deficits in subjects with age-associated cognitive decline or a dementing illness includes administering to the subject a therapeutically effective amount of amylin, an amylin agonist, or an amylin derivative to treat the cognitive impairment or deficit.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: June 20, 2017
    Assignee: Case Western Reserve University
    Inventors: Gemma Casadesus Smith, Brittany Adler, Mark Yarchoan
  • COMPOSITIONS AND METHODS FOR TREATING COGNITIVE DEFICITS
    Publication number: 20150374792
    Abstract: A method of treating or preventing cognitive impairment deficits in subjects with age-associated cognitive decline or a dementing illness includes administering to the subject a therapeutically effective amount of amylin, an amylin agonist, or an amylin derivative to treat the cognitive impairment or deficit.
    Type: Application
    Filed: September 14, 2015
    Publication date: December 31, 2015
    Inventors: Gemma Casadesus Smith, Brittany Adler, Mark Yarchoan
  • Compositions and methods for treating cognitive deficits
    Patent number: 9132170
    Abstract: A method of treating or preventing cognitive impairment deficits in subjects with age-associated cognitive decline or a dementing illness includes administering to the subject a therapeutically effective amount of amylin, an amylin agonist, or an amylin derivative to treat the cognitive impairment or deficit.
    Type: Grant
    Filed: July 30, 2012
    Date of Patent: September 15, 2015
    Assignee: Case Western Reserve University
    Inventors: Gemma Casadesus Smith, Brittany Adler, Mark Yarchoan
  • COMPOSITIONS AND METHODS FOR TREATING COGNITIVE DEFICITS
    Publication number: 20130190230
    Abstract: A method of treating or preventing cognitive impairment deficits in subjects with age-associated cognitive decline or a dementing illness includes administering to the subject a therapeutically effective amount of amylin, an amylin agonist, or an amylin derivative to treat the cognitive impairment or deficit.
    Type: Application
    Filed: July 30, 2012
    Publication date: July 25, 2013
    Applicant: Case Western Reserve University
    Inventors: Gemma Casadesus Smith, Brittany Adler, Mark Yarchoan