Patents by Inventor Mark Zdeblick
Mark Zdeblick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11950615Abstract: An apparatus includes a food product, at least one ingestible device associated with the food product to communicate information and at least one coating material surrounding the at least one ingestible device is disclosed. The ingestible device is associated with an ingestible medication to be ingested in conjunction with the food product. The coating is configured to release the at least one ingestible device upon the occurrence of an event.Type: GrantFiled: November 10, 2021Date of Patent: April 9, 2024Assignee: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Lawrence Arne, Mark Zdeblick, Aditya Dua, George Savage, Robert Leichner, Jafar Shenasa, Patricia Johnson, Raymond Schmidt, Zahedeh Hatamkhany, Veeraperumanallu Muralidharan
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Publication number: 20230216595Abstract: An apparatus that includes a partial power source including a first material and a second material, the partial power source configured to generate, upon contact with a conducting medium, a potential difference between the first material and the second material to provide power to a control device, and generate, using the first material and the second material, a current flow within the conducting medium, the current flow including information encoded based on a variable conductance between the first material and the second material.Type: ApplicationFiled: August 24, 2022Publication date: July 6, 2023Applicant: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Mark ZDEBLICK, Andrew THOMPSON, Aleksandr PIKELNY, Timothy L. ROBERTSON, Hooman HAFEZI
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Publication number: 20220346664Abstract: Methods, devices and systems for acquiring information useful to support a patient in implementing and adhering to a medically prescribed therapy plan are provided. The therapy may incorporate biofeedback methods and/or personalized therapy aspects. A method includes steps of receiving, by a receiving device, biometric information associated with an ingestible event marker; analyzing, by a computing device having a microprocessor configured to perform a biometric information analysis, the biometric information; and determining a therapeutic recommendation at least partly on the basis of the analysis and/or integrating biofeedback techniques into patient therapy or activity. A system includes a biometric information module to receive biometric information associated with an ingestible event marker; an analysis module to analyze the biometric information; and a determination module to optionally determine and communicate a therapeutic recommendation at least partly on the basis of the analysis.Type: ApplicationFiled: July 14, 2022Publication date: November 3, 2022Applicant: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Marc JENSEN, Robert LEICHNER, Patrick BEAULIEU, Kityee AU-YEUNG, Lawrence ARNE, Mark ZDEBLICK, Andrew THOMPSON, George SAVAGE, Timothy ROBERTSON, Yashar BEHZADI
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Patent number: 11476952Abstract: An apparatus that includes a partial power source including a first material and a second material, the partial power source configured to generate, upon contact with a conducting medium, a potential difference between the first material and the second material to provide power to a control device, and generate, using the first material and the second material, a current flow within the conducting medium, the current flow including information encoded based on a variable conductance between the first material and the second material.Type: GrantFiled: October 5, 2020Date of Patent: October 18, 2022Assignee: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Mark Zdeblick, Andrew Thompson, Aleksandr Pikelny, Timothy L. Robertson, Hooman Hafezi
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Publication number: 20220323364Abstract: Controlled activation identifiers for use in ingestible compositions, such as pharma-informatics enabled compositions, are provided. The identifiers include a controlled activation element that provides for activation of the identifier in response to the presence of a predetermined stimulus at a target site of interest. The invention finds use in a variety of different applications, including but not limited to, monitoring of therapeutic regimen compliance, tracking the history of pharmaceutical agents, etc.Type: ApplicationFiled: May 10, 2022Publication date: October 13, 2022Applicant: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Hooman Hafezi, Timothy Robertson, Olivier Colliou, Mark Zdeblick
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Publication number: 20220189606Abstract: The ingestible event marker data framework provides a uniform, comprehensive framework to enable various functions and utilities related to ingestible event marker data (IEM data). The functions and utilities include data and/or information having an aspect of data derived from, collected by, aggregated by, or otherwise associated with, an ingestion event.Type: ApplicationFiled: November 29, 2021Publication date: June 16, 2022Applicant: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: David O'Reilly, Erika Karplus, Andrew Thompson, George Savage, Mark Zdeblick, Timothy Robertson, Lawrence Arne, Yashar Behzadi, Gregory Moon, Patrick Beaulieu
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Patent number: 11357730Abstract: Apparatuses for use with a pharmaceutically acceptable carrier. The apparatus can include a partial power source, which in turn includes electrodes or materials that are configured to generate an electrical potential upon contacting or being exposed to an ionic solution. The apparatus can further include a circuit electrically or communicatively coupled to the partial power source. The circuit can generate various types of signals, such as RF signals, when powered by the partial power source. The circuit is stably fittable to the pharmaceutically acceptable carrier. The apparatus can further include a barrier, a protective layer, or a membrane that isolates the electrodes or materials from the ionic solution and is configured to be dissolved by the ionic solution.Type: GrantFiled: December 28, 2018Date of Patent: June 14, 2022Assignee: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Hooman Hafezi, Timothy Robertson, Olivier Colliou, Mark Zdeblick
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Publication number: 20220116124Abstract: The present disclosure includes ingestible devices. In some examples, an ingestible device is presented that includes a framework, a control device secured to the framework, and a partial power source. The partial power source may include a first digestible material secured to the framework and electrically coupled to the control device, and a second digestible material electrically isolated from and dissimilar to the first digestible material, electrically coupled to the control device, and secured to the framework. The partial power source may be configured to provide power to the control device when the first and second digestible materials come in contact with a conductive fluid. The control device, after being provided power by the first and second digestible materials, may be configured to alter conductance between the first and second digestible materials to produce a current signature through the conductive fluid that is detectable by a receiver.Type: ApplicationFiled: May 20, 2021Publication date: April 14, 2022Applicant: OTSUKA PHARMACEUTICALInventors: Mark ZDEBLICK, Timothy ROBERTSON, Aleksandr PIKELNY, Hooman HAFEZI
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Publication number: 20220061369Abstract: An apparatus includes a food product, at least one ingestible device associated with the food product to communicate information and at least one coating material surrounding the at least one ingestible device is disclosed. The ingestible device is associated with an ingestible medication to be ingested in conjunction with the food product. The coating is configured to release the at least one ingestible device upon the occurrence of an event.Type: ApplicationFiled: November 10, 2021Publication date: March 3, 2022Applicant: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Lawrence Arne, Mark Zdeblick, Aditya Dua, George Savage, Robert Leichner, Jafar Shenasa, Patricia Johnson, Raymond Schmidt, Zahedeh Hatamkhany, Veeraperumanallu Muralidharan
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Patent number: 11217342Abstract: The ingestible event marker data framework provides a uniform, comprehensive framework to enable various functions and utilities related to ingestible event marker data (IEM data). The functions and utilities include data and/or information having an aspect of data derived from, collected by, aggregated by, or otherwise associated with, an ingestion event.Type: GrantFiled: April 26, 2017Date of Patent: January 4, 2022Assignee: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: David O'Reilly, Erika Karplus, Andrew Thompson, George Savage, Mark Zdeblick, Timothy Robertson, Lawrence Arne, Yashar Behzadi, Gregory Moon, Patrick Beaulieu
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Patent number: 11197492Abstract: An apparatus includes a food product, at least one ingestible device associated with the food product to communicate information and at least one coating material surrounding the at least one ingestible device is disclosed. The ingestible device is associated with an ingestible medication to be ingested in conjunction with the food product. The coating is configured to release the at least one ingestible device upon the occurrence of an event.Type: GrantFiled: July 17, 2019Date of Patent: December 14, 2021Assignee: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Lawrence Arne, Mark Zdeblick, Aditya Dua, George Savage, Robert Leichner, Jafar Shenasa, Patricia Johnson, Raymond Schmidt, Zahedeh Hatamkhany, Veeraperumanallu Muralidharan
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Publication number: 20210273734Abstract: An apparatus that includes a partial power source including a first material and a second material, the partial power source configured to generate, upon contact with a conducting medium, a potential difference between the first material and the second material to provide power to a control device, and generate, using the first material and the second material, a current flow within the conducting medium, the current flow including information encoded based on a variable conductance between the first material and the second material.Type: ApplicationFiled: October 5, 2020Publication date: September 2, 2021Inventors: Mark ZDEBLICK, Andrew THOMPSON, Aleksandr PIKELNY, Timothy L. ROBERTSON, Hooman HAFEZI
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Patent number: 11102038Abstract: A method may comprise receiving and sampling a signal. The signal may encode a data packet. A slice may be generated and stored comprising a pair of values for each of a selected number of samples of the signal representing a correlation of the signal to reference functions in the receiver. The presence of the data packet may then be detected and the detected packet decoded from the stored slices. The generating and storing slices may be carried out as the received signal is sampled. The sampled values of the signal may be discarded as the slices are generated and stored. The slice representation of the signal can be manipulated to generate filters with flexible bandwidth and center frequency.Type: GrantFiled: October 11, 2019Date of Patent: August 24, 2021Assignee: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Robert Fleming, Cherie Kushner, William H. McAllister, Mark Zdeblick
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Patent number: 11044024Abstract: The system of the present invention includes a conductive element, an electronic component, and a partial power source in the form of dissimilar materials. Upon contact with a conducting fluid, a voltage potential is created and the power source is completed, which activates the system. The electronic component controls the conductance between the dissimilar materials to produce a unique current signature. The system can be used in a variety of different applications, including as components of ingestible identifiers, such as may be found in ingestible event markers, e.g., pharma-informatics enabled pharmaceutical compositions.Type: GrantFiled: December 18, 2019Date of Patent: June 22, 2021Assignee: Proteus Digital Health, Inc.Inventors: Mark Zdeblick, Timothy Robertson, Aleksandr Pikelny, Hooman Hafezi
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Patent number: 10797758Abstract: Provided is an electronic device having a control device, a driver circuit coupled to the control device. The driver circuit is configured to alter conductance. A partial power source is coupled to the control device and is configured to provide a voltage potential difference to the control device and the driver circuit as a result of the partial power source being in contact with a conductive fluid. The partial power source includes a first material electrically coupled to the control device and a second material electrically coupled to the control device and electrically isolated from the first material. An inductor is coupled to the driver circuit. The driver circuit is configured to develop a current through the inductor. The magnitude of the current developed through the inductor is varied to produce an encoded signal that is remotely detectable by a receiver. Receivers to receive and decode also are disclosed.Type: GrantFiled: January 10, 2019Date of Patent: October 6, 2020Inventors: Alireza Shirvani, Mark Zdeblick, Jonathan Withrington
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Publication number: 20200259691Abstract: A method may comprise receiving and sampling a signal. The signal may encode a data packet. A slice may be generated and stored comprising a pair of values for each of a selected number of samples of the signal representing a correlation of the signal to reference functions in the receiver. The presence of the data packet may then be detected and the detected packet decoded from the stored slices. The generating and storing slices may be carried out as the received signal is sampled. The sampled values of the signal may be discarded as the slices are generated and stored. The slice representation of the signal can be manipulated to generate filters with flexible bandwidth and center frequency.Type: ApplicationFiled: October 11, 2019Publication date: August 13, 2020Inventors: Robert Fleming, Cherie Kushner, William H. McAllister, Mark Zdeblick
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Patent number: 10720044Abstract: A headwear device for detecting an electrical signal generated by an ingestible event marker is disclosed. The headwear device includes a detection subsystem to receive an electrical signal generated by an ingestible event marker from a detection arrangement. A processing subsystem is coupled to the detection subsystem to decode the electrical signal. A radio subsystem is configured to transmit the decoded electrical signal to a wireless node. A system includes the headwear device and the detection arrangement. A method includes receiving the electrical signal generated by the ingestible event marker at the headwear device, decoding the electrical signal to extract information associated with the ingestible event marker, and transmitting the information to a wireless node.Type: GrantFiled: January 24, 2019Date of Patent: July 21, 2020Assignee: PROTEUS DIGITAL HEALTH, INC.Inventors: Mark Zdeblick, Arna Ionescu Stoll, William McAllister, Kit Yee Au-Yeung
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Publication number: 20200121220Abstract: The system of the present invention includes a conductive element, an electronic component, and a partial power source in the form of dissimilar materials. Upon contact with a conducting fluid, a voltage potential is created and the power source is completed, which activates the system. The electronic component controls the conductance between the dissimilar materials to produce a unique current signature. The system can be used in a variety of different applications, including as components of ingestible identifiers, such as may be found in ingestible event markers, e.g., pharma-informatics enabled pharmaceutical compositions.Type: ApplicationFiled: December 18, 2019Publication date: April 23, 2020Inventors: Mark ZDEBLICK, Timothy ROBERTSON, Aleksandr PIKELNY, Hooman HAFEZI
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Patent number: 10610128Abstract: A system for administering prescription medications including a composition and a receiver. The composition may include an active agent, an identifier, and a pharmaceutically acceptable carrier. The active agent may include a controlled pharmaceutical. The identifier may include: a partial power source having a first material and a second material configured to generate a voltage in contact with a conductive fluid within a body of a patient, and a signal generation component configured to use at least a portion of the generated voltage to transmit a signal through the body of the patient. The receiver may be positioned near the body of the patient, wherein the receiver is configured to: receive the signal transmitted through the body of the patient, and automatically report the signal for at least one of identification of the controlled pharmaceutical or tracking physical administration of the controlled pharmaceutical to the body of the patient.Type: GrantFiled: October 20, 2017Date of Patent: April 7, 2020Assignee: PROTEUS DIGITAL HEALTH, INC.Inventors: Mark Zdeblick, Andrew Thompson, Aleksandr Pikelny, Timothy L. Robertson, Hooman Hafezi
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Publication number: 20200093168Abstract: An apparatus includes a food product, at least one ingestible device associated with the food product to communicate information and at least one coating material surrounding the at least one ingestible device is disclosed. The ingestible device is associated with an ingestible medication to be ingested in conjunction with the food product. The coating is configured to release the at least one ingestible device upon the occurrence of an event.Type: ApplicationFiled: July 17, 2019Publication date: March 26, 2020Inventors: Lawrence Arne, Mark Zdeblick, Aditya Dua, George Savage, Robert Leichner, Jafar Shenasa, Patricia Johnson, Raymond Schmidt, Zahedeh Hatamkhany, Veeraperumanallu Muralidharan