Patents by Inventor Markku Jeltsch

Markku Jeltsch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Materials and Methods Involving Hybrid Vascular Endothelial Growth Factor DNAs and Proteins
    Publication number: 20080058263
    Abstract: The present invention provides polypeptides that bind cellular receptors for vascular endothelial growth factor polypeptides; polynucleotides encoding such polypeptides; compositions comprising the polypeptides and polynucleotides; and methods and uses involving the foregoing. Some polypeptides of the invention exhibit unique receptor binding profiles compared to known, naturally occurring vascular endothelial growth factors.
    Type: Application
    Filed: August 28, 2007
    Publication date: March 6, 2008
    Applicants: LUDWIG INSTITUTE FOR CANCER RESEARCH, LICENTIA LTD.
    Inventors: Kari Alitalo, Markku Jeltsch
  • Modified VEGF-A with improved angiogenic properties
    Publication number: 20070142282
    Abstract: The present invention is directed to methods and compositions for making and using chimeric polypeptides that comprise a VEGFR-2 ligand. The chimeric molecules of the present invention retain VEGFR-2 binding activity and an enhanced angiogenic activity as compared to native VEGF-A.
    Type: Application
    Filed: August 15, 2006
    Publication date: June 21, 2007
    Applicants: LUDWIG INSTITUTE FOR CANCER RESEARCH, LICENTIA LTD.
    Inventors: Kari Alitalo, Tuomas Tammela, Salla Keskitalo, Katri Pajusola, Markku Jeltsch, Seppo Yla-Herttuala, Terhi Karpanen, Ulf Eriksson, Marko Uutela
  • Growth factor binding constructs materials and methods
    Publication number: 20060030000
    Abstract: The present invention provides materials and methods for antagonizing the function of vascular endothelial growth factor receptors, platelet derived growth factor receptors and other receptors. Soluble binding constructs able to bind vascular endothelial growth factors, platelet derived growth factors, and other ligands are provided.
    Type: Application
    Filed: March 7, 2005
    Publication date: February 9, 2006
    Applicants: LUDWIG INSTITUTE FOR CANCER RESEARCH, LICENTIA, LTD.
    Inventors: Kari Alitalo, Markku Jeltsch
  • Materials and methods involving hybrid vascular endothelial growth factor DNAs and proteins
    Publication number: 20050267024
    Abstract: The present invention provides polypeptides that bind cellular receptors for vascular endothelial growth factor polypeptides; polynucleotides encoding such polypeptides; compositions comprising the polypeptides and polynucleotides; and methods and uses involving the foregoing. Some polypeptides of the invention exhibit unique receptor binding profiles compared to known, naturally occurring vascular endothelial growth factors.
    Type: Application
    Filed: February 24, 2005
    Publication date: December 1, 2005
    Applicants: LUDWIG INSTITUTE FOR CANCER RESEARCH, LICENTIA, LTD.
    Inventors: Kari Alitalo, Markku Jeltsch
  • Use of VEGF-C or VEGF-D gene or protein to prevent restenosis
    Publication number: 20050256075
    Abstract: The present invention provides materials and methods for preventing stenosis or restenosis of a blood vessel using Vascular Endothelial Growth Factor C (VEGF-C) and/or Vascular Endothelial Growth Factor D (VEGF-D) genes or proteins.
    Type: Application
    Filed: February 24, 2005
    Publication date: November 17, 2005
    Inventors: Kari Alitalo, Seppo Yla-Herttuala, Mikko Hiltunen, Markku Jeltsch, Marc Achen