Patents by Inventor Markku La Saloheimo

Markku La Saloheimo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Increased production of secreted proteins by recombinant eukaryotic cells
    Patent number: 8753866
    Abstract: Described herein are methods for increasing the amount of protein secreted by a cell. In one case, a cell is provided which contains a heterologous nucleic acid encoding a protein having unfolded protein response modulating activity and a heterologous nucleic acid encoding a protein of interest to be secreted. In one case, the protein having unfolded protein response modulating activity is selected from the proteins selected from the group consisting of HAC1, PTC2 and IRE1. The protein of interest can be any secreted protein such as a therapeutic or an industrial enzyme. For example the protein can be selected from the group consisting of lipase, cellulase, endo-glucosidase H, protease, carbohydrase, reductase, oxidase, isomerase, transferase, kinase, phosphatase, alpha-amylase, glucoamylase, lignocellulose hemicellulase, pectinase and ligninase.
    Type: Grant
    Filed: December 16, 2009
    Date of Patent: June 17, 2014
    Assignee: Danisco US Inc.
    Inventors: Merja E. Penttila, Michael Ward, Huaming Wang, Mari J. Valkonen, Markku La Saloheimo
  • Xylanase from Trichoderma reesei , method for production thereof, and methods employing this enzyme
    Patent number: 6555335
    Abstract: The present invention is directed to novel xylanases (referred to as XYL-IV) and to nucleic acid molecules encoding those xylanases. Also provided herein are vectors and host cells including those nucleic acid sequences, antibodies which bind to the xylanases of the present invention, methods for producing the xylanases of the present invention, and methods employing the xylanases of the present invention.
    Type: Grant
    Filed: September 11, 2000
    Date of Patent: April 29, 2003
    Assignee: Genencor International, Inc.
    Inventors: Markku La Saloheimo, Matti Siika-Aho, Maija Tenkanen, Merja E. Penttila
  • Novel xylanase from trichoderma reesei, method for production thereof, and methods employing this enzyme
    Publication number: 20030054518
    Abstract: The present invention is directed to novel xylanases (referred to as XYL-IV) and to nucleic acid molecules encoding those xylanases. Also provided herein are vectors and host cells including those nucleic acid sequences, antibodies which bind to the xylanases of the present invention, methods for producing the xylanases of the present invention, and methods employing the xylanases of the present invention.
    Type: Application
    Filed: May 31, 2002
    Publication date: March 20, 2003
    Inventors: Markku La Saloheimo, Matti Siika-Aho, Maija Tenkanen, Merja E. Penttila