Patents by Inventor Marko Ahlmark

Marko Ahlmark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TEAD INHIBITORS
    Publication number: 20240246908
    Abstract: The present invention relates to a compound of formula (I) wherein A, Z, L, R1, R2, R3, R4, R5 and R33 are as defined in claim 1, or a pharmaceutically acceptable salt thereof. The compounds of formula (I) possess utility as inhibitors of TEAD. The compounds are useful as medicaments in the treatment of diseases or conditions wherein inhibition of TEAD is desired, such as cancer and chronic pain.
    Type: Application
    Filed: April 14, 2022
    Publication date: July 25, 2024
    Inventors: Marko AHLMARK, David DIN BELLE, Dimitris NOUTSIAS, Pekka PIETIKÄINEN, Petteri RUMMAKKO, Julius SIPILÄ, Gerd WOHLFAHRT
  • CATECHOL O-METHYLTRANSFERASE ACTIVITY INHIBITING COMPOUNDS
    Publication number: 20220047540
    Abstract: Compounds of formula (I), wherein R1 is as defined in the claims, exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors. Methods of treatment and pharmaceutical dosage forms are also disclosed.
    Type: Application
    Filed: September 1, 2021
    Publication date: February 17, 2022
    Inventors: Marko AHLMARK, David DIN BELLE, Mika KAUPPALA, Anne LUIRO, Taina PAJUNEN, Jarmo PYSTYNEN, Eija TIAINEN, Matti VAISMAA, Josef MESSINGER
  • CATECHOL O-METHYLTRANSFERASE ACTIVITY INHIBITING COMPOUNDS
    Publication number: 20200352898
    Abstract: Compounds of formula (I), wherein R1 is as defined in the claims, exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors. Methods of treatment and pharmaceutical dosage forms are also disclosed.
    Type: Application
    Filed: June 5, 2020
    Publication date: November 12, 2020
    Inventors: Marko AHLMARK, David DIN BELLE, Mika KAUPPALA, Anne LUIRO, Taina PAJUNEN, Jarmo PYSTYNEN, Eija TIAINEN, Matti VAISMAA, Josef MESSINGER
  • CATECHOL O-METHYLTRANSFERASE ACTIVITY INHIBITING COMPOUNDS
    Publication number: 20200009103
    Abstract: Compounds of formula (I), wherein R1 is as defined in the claims, exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors. Methods of treatment and pharmaceutical dosage forms are also disclosed.
    Type: Application
    Filed: May 17, 2019
    Publication date: January 9, 2020
    Inventors: Marko AHLMARK, David DIN BELLE, Mika KAUPPALA, Anne LUIRO, Taina PAJUNEN, Jamo PYSTYNEN, Eija TIAINEN, Matti VAISMAA, Josef MESSINGER
  • CATECHOL O-METHYLTRANSFERASE ACTIVITY INHIBITING COMPOUNDS
    Publication number: 20190029990
    Abstract: Compounds of formula (I), wherein R1 is as defined in the claims, exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors. Methods of treatment and pharmaceutical dosage forms are also disclosed.
    Type: Application
    Filed: July 30, 2018
    Publication date: January 31, 2019
    Inventors: Marko Ahlmark, David Din Belle, Mika Kauppala, Anne Luiro, Taina Pajunen, Jarmo Pystynen, Eija Tiainen, Matti Vaismaa, Josef Messinger
  • CATECHOL O-METHYLTRANSFERASE ACTIVITY INHIBITING COMPOUNDS
    Publication number: 20170165219
    Abstract: Compounds of formula (I), wherein R1 is as defined in the claims, exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors. Methods of treatment and pharmaceutical dosage forms are also disclosed.
    Type: Application
    Filed: August 2, 2016
    Publication date: June 15, 2017
    Inventors: Marko AHLMARK, David DIN BELLE, Mika KAUPPALA, Anne LUIRO, Taina PAJUNEN, Jarmo PYSTYNEN, Eija TIAINEN, Matti VAISMAA, Josef MESSINGER
  • Catechol O-methyltransferase activity inhibiting compounds
    Patent number: 9458128
    Abstract: Compounds of formula (I), wherein R1 is as defined in the claims, exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors. Methods of treatment and pharmaceutical dosage forms are also disclosed.
    Type: Grant
    Filed: May 23, 2013
    Date of Patent: October 4, 2016
    Assignee: ORION CORPORATION
    Inventors: Marko Ahlmark, David Din Belle, Mika Kauppala, Anne Luiro, Taina Pajunen, Jarmo Pystynen, Eija Tiainen, Matti Vaismaa, Josef Messinger
  • CATECHOL O-METHYLTRANSFERASE ACTIVITY INHIBITING COMPOUNDS
    Publication number: 20150218124
    Abstract: Compounds of formula (I), wherein R1 is as defined in the claims, exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors. Methods of treatment and pharmaceutical dosage forms are also disclosed.
    Type: Application
    Filed: May 23, 2013
    Publication date: August 6, 2015
    Inventors: Marko Ahlmark, David Din Belle, Mika Kauppala, Anne Luiro, Taina Pajunen, Jarmo Pystynen, Eija Tianen, Matti Vaismaa, Josef Messinger
  • Pharmaceutical compounds
    Patent number: 8318785
    Abstract: Compounds of formula (I) exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors.
    Type: Grant
    Filed: July 17, 2006
    Date of Patent: November 27, 2012
    Assignee: Orion Corporation
    Inventors: Marko Ahlmark, Reijo Bäckström, Anne Luiro, Jarmo Pystynen, Eija Tiainen
  • PHARMACEUTICAL COMPOUNDS
    Publication number: 20110086852
    Abstract: Compounds of formula (I), wherein R1-R4, X, Y and Z are as defined in claims, exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors.
    Type: Application
    Filed: July 17, 2006
    Publication date: April 14, 2011
    Applicant: Orion Corporation
    Inventors: Marko AHLMARK, Reijo BACKSTROM, Anne LUIRO, Jarmo PYSTYNEN, Eija TIAINEN
  • PHARMACEUTICAL COMPOUNDS
    Publication number: 20090209532
    Abstract: Compounds of formula (I) exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors.
    Type: Application
    Filed: July 17, 2006
    Publication date: August 20, 2009
    Inventors: Marko Ahlmark, Reijo Backstrom, Anne Luiro, Jarmo Pystynen, Eija Tiainen
  • Methylenebisphosphonic acid derivatives
    Patent number: 6326363
    Abstract: The object of the invention are novel halogen substituted methylenebisphosphonic acid anhydrides, ester anhydrides, amide anhydrides, and ester amide anhydrides, processes for the preparation of these novel compounds, as well as pharmaceutical preparations comprising these novel compounds.
    Type: Grant
    Filed: July 12, 2000
    Date of Patent: December 4, 2001
    Assignee: Leiras Oy
    Inventors: Esko Pohjala, Heikki Nupponen, Leena Laurén, Ritva Hannuniemi, Jouko Vepsäläinen, Jouni Kähkönen, Tomi Järvinen, Marko Ahlmark