Abstract: A computer-implemented method can be used for monitoring spray delivery of drug-containing liquid for remedying a discomfort. The method involves a) receiving first input data, the first input data containing a number of delivered puffs as detected by a counter of a spray device during an intake period, b) receiving second input data containing user state data representative of self-reported perceived discomfort level, particularly pain level, and/or self-reported perceived side effect severity during the intake period, the user state data being obtained from a user input via a user interface of an application, c) determining, based at least on the first input data and the second input data, a suggested number of delivered puffs for an upcoming intake period, and d) outputting, via the user interface, user instructions indicating the suggested number of delivered puffs.