Abstract: A wheel spoke adjuster guard for protecting wheel spokes, wheel spoke adjuster lugs, and the wheel rim openings through which the adjuster lugs are recieved, of motorcycles, bicycles and the like, from the intrusion of foreign materials. The spoke adjuster guard comprises a plurality of semi-tubular sections adapted for lockable engagement to wrap around and closely surround the spoke adjuster lug and a portion of the adjacent wheel spoke, including the threaded end receivable in the spoke adjuster lug. Upon lockable engagement, the sections also engage the spoke so as to remain fixedly in place to protectively cover the spoke adjuster lug, the threaded end of the spoke, and the wheel rim opening receiving the spoke adjuster lug.