Patents by Inventor Markus ALESCHKO

Markus ALESCHKO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210371835
    Abstract: The present invention relates to a method for increasing the stability of an ?/?-hydrolase. In addition, the present invention relates to an ?/?-hydrolase obtainable by the method of the present invention. Also provided are ?/?-hydrolases having a decreased grand average of hydropathy (GRAVY) value and/or comprising specific mutations. In addition, the present invention concerns a use of an ?/?-hydrolase of the present invention for degrading zearalenone (ZEN).
    Type: Application
    Filed: July 30, 2019
    Publication date: December 2, 2021
    Inventors: Michaela Thamhesl, Sebastian Fruhauf, Wulf-Dieter Moll, Andreas Hoebartner, Gerd Schatzmayr, Eva Maria Binder, Markus Aleschko, Martin Pfeffer
  • Patent number: 10264807
    Abstract: The invention relates to fusarium toxin-cleaving polypeptide variants of a fusarium toxin carboxyl esterase with the SEQ ID NO:46. Each of the polypeptide variants has an amino acid sequence shortened by 47 amino acids at the N terminus, and the amino acid sequences have at least 70%, preferably 80%, in particular 100%, sequence identity, namely SEQ ID NO:1, to the amino acid sequence portion 48-540 of the SEQ ID NO:46. The invention also relates to isolated polynucleotides which code for the polypeptide variants, to a fusarium toxin-cleaving additive containing at least one polypeptide variant and optionally at least one auxiliary agent, to the use of the polypeptide variants or the additive, and to a method for hydrolytically cleaving at least one fusarium toxin.
    Type: Grant
    Filed: February 24, 2015
    Date of Patent: April 23, 2019
    Assignee: ERBER AKTIENGESELLSCHAFT
    Inventors: Markus Aleschko, Corinna Kern, Dieter Moll, Eva Maria Binder, Gerd Schatzmayr
  • Publication number: 20180235255
    Abstract: The invention relates to fusarium toxin-cleaving polypeptide variants of a fusarium toxin carboxyl esterase with the SEQ ID NO:46. Each of the polypeptide variants has an amino acid sequence shortened by 47 amino acids at the N terminus, and the amino acid sequences have at least 70%, preferably 80%, in particular 100%, sequence identity, namely SEQ ID NO:1, to the amino acid sequence portion 48-540 of the SEQ ID NO:46. The invention also relates to isolated polynucleotides which code for the polypeptide variants, to a fusarium toxin-cleaving additive containing at least one polypeptide variant and optionally at least one auxiliary agent, to the use of the polypeptide variants or the additive, and to a method for hydrolytically cleaving at least one fusarium toxin.
    Type: Application
    Filed: February 24, 2015
    Publication date: August 23, 2018
    Applicant: ERBER AKTIENGESELLSCHAFT
    Inventors: Markus ALESCHKO, Corinna KERN, Dieter MOLL, Eva Maria BINDER, Gerd SCHATZMAYR