Patents by Inventor Markus BAENZIGER

Markus BAENZIGER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR THE SYNTHESIS OF PYRAZOLYL DERIVATIVES USEFUL AS ANTI-CANCER AGENTS
    Publication number: 20250101006
    Abstract: The invention provides a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially KRAS G12C inhibitors. The present invention provides a direct enantioselective chemical manufacturing method of making Compound A, or a pharmaceutically acceptable hydrate or solvent thereof: (I). The invention provides a process for preparing Intermediate B6* comprising reacting Intermediate B4* with Intermediate B5* in an atroposelective coupling reaction, using a chiral catalyst.
    Type: Application
    Filed: January 30, 2023
    Publication date: March 27, 2025
    Inventors: Markus BAENZIGER, Fabrice GALLOU, Fengfeng GUO, Rudolf HÄNGGI, Enjian HAN, Guido JORDINE, Jialiang LI, Weipeng LIU, Bukeyan MIAO, Shaofeng RONG, Ernesto SANTANDREA, Paul Bernd SCHIRNER, Xiaodong SHEN, Can WANG, Hao ZHANG