Patents by Inventor Markus Dangl

Markus Dangl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MRNA-based gene expression for personalizing patient cancer therapy with an MDM2 antagonist
    Patent number: 9657351
    Abstract: Use of at least an MDM2 gene panel, preferably a four gene MDM2 gene panel, as a biomarker for predicting the response to a MDM2 antagonist.
    Type: Grant
    Filed: December 4, 2014
    Date of Patent: May 23, 2017
    Assignee: HOFFMAN-LA ROCHE INC.
    Inventors: Hua Zhong, David Geho, Gong Chen, Gwen Nichols, Markus Dangl
  • Combination therapy of an anti-CD20 antibody with a Bcl-2 inhibitor and a MDM2 inhibitor
    Publication number: 20160347852
    Abstract: The present invention is directed to the combination therapy of an anti-CD20 antibody with a Bcl-2 inhibitor and a MDM2 inhibitor for the treatment of cancer, especially to the combination therapy of CD20 expressing cancers with a type I anti-CD20 antibody or an afucosylated humanized B-Ly1 antibody and a Bcl-2 inhibitor and a MDM2 inhibitor.
    Type: Application
    Filed: May 26, 2016
    Publication date: December 1, 2016
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Christian Klein, Frank Herting, Markus Dangl
  • MRNA-BASED GENE EXPRESSION FOR PERSONALIZING PATIENT CANCER THERAPY WITH AN MDM2 ANTAGONIST
    Publication number: 20150211073
    Abstract: Use of at least an MDM2 gene panel, preferably a four gene MDM2 gene panel, as a biomarker for predicting the response to a MDM2 antagonist.
    Type: Application
    Filed: December 4, 2014
    Publication date: July 30, 2015
    Inventors: Hua Zhong, David Geho, Gong Chen, Gwen Nichols, Markus Dangl
  • INTERFERENCE REDUCTION IN A COMMUNICATION SIGNAL
    Publication number: 20090220016
    Abstract: The invention concerns the reduction of interference in a communication signal sent through a communication channel, where this interference is a performance limiting factor. The communication channel is any channel that can be described with memory elements. A Soft Input Soft Output receiver of a communication signal receives the communication signal and a priori information about the communication signal. Next creating candidate vectors having 1 to K samples by iteratively drawing samples using Gibbs sampling and using the a priori information. If a drawn kth sample of a candidate vector has not changed value for a predetermined number of created candidate vectors, then the value of the drawn kth sample is changed.
    Type: Application
    Filed: August 30, 2006
    Publication date: September 3, 2009
    Applicant: National ICT Australia Limited
    Inventors: Markus Dangl, Zhenning Shi, Mark Reed