Patents by Inventor Markus Enderle

Markus Enderle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240074695
    Abstract: A treatment device allows a treatment of tissue with a treatment medium that does not directly show a tissue trace with manual as well as machine instrument guidance and under adjustment of a treatment plan map, due to preceding treatments. The treatment plan map represents the transformation rules for the treating person. The concept allows the adaption to different patients or patient collectives as well as the individualization of the creation of the treatment plan map with regard to the using treating persons.
    Type: Application
    Filed: August 29, 2023
    Publication date: March 7, 2024
    Inventors: Yannick Daniel, Markus Enderle, Ovidiu Jurjut, Elena Leonberger
  • Patent number: 11918733
    Abstract: A medical instrument with an aerosol outlet, which is fluidically connected—via an aerosol line—to a generation device. The generation device is adapted to generate aerosol for dispensing by means of the medical instrument. In addition, a generation device is stated, which, in embodiments of the generation device, for example can be used in a device with the instrument according to the invention. The generation device comprises a mixing unit for mixing a liquid and a gas together, which mixing unit is connected to a liquid container for supplying the mixing unit with a liquid, in which case the generation device is adapted to utilize the gas pressure of a gas under pressure subjecting the liquid to a pressure in order to press the liquid out of the liquid container to the mixing unit.
    Type: Grant
    Filed: September 25, 2019
    Date of Patent: March 5, 2024
    Assignee: ERBE ELEKTROMEDIZIN GMBH
    Inventors: Alexander Neagos, Markus Enderle, Christian Schaefer
  • Publication number: 20220273278
    Abstract: A retrieve device for retrieving tissue having a retrieve bag that is at least in part a hydrophilic water permeable filter diaphragm. The filter diaphragm may have a pore width that allows for blocking passage of pathogen cells or other pathogen material. The pores width may also be large enough to allow water to exit out of the retrieve bag. Liquid in the retrieve bag can be expelled through the filter diaphragm and thus does not contribute the volume of the retrieve bag.
    Type: Application
    Filed: February 15, 2022
    Publication date: September 1, 2022
    Applicant: Erbe Elektromedizin GmbH
    Inventors: Uwe Schnitzler, Markus Enderle
  • Patent number: 11357406
    Abstract: The instrument according to the invention for electrosurgically impacting biological tissue comprises an electrode (18) as well as a light guide (21), which is connected to a light inlet window (19), which is formed by means of a fluid body (27). The light guide is connected to a light analysis device (13), so as to absorb the light, which is generated at the electrode (18) in response to the HF surgery and so as to supply it to the light analysis device (13). The light inlet window (19) is arranged at the point of origin of the light, namely immediately at the electrode, that is, at the spark, which is generated. An adulteration of the absorbed light by means of smoke or particle deposition on the light inlet window (19) can virtually be avoided.
    Type: Grant
    Filed: November 26, 2018
    Date of Patent: June 14, 2022
    Assignee: Erbe Elektromedizin GmbH
    Inventors: Klaus Fischer, Alexander Neugebauer, Dominik Spether, Markus Enderle
  • Patent number: 11229476
    Abstract: A cryosurgical instrument, in particular a biopsy instrument for transbronchial biopsy, having an elongated instrument base body with a distal and proximal end, in relation to the operational position, a cooled section close to the distal end and which removes tissue, said section being designed such that surrounding biological material adheres thereto, by means of cryoadhesion, when said instrument is in use in the cooled state, and a security section which is provided at a distance from the tissue removal section and which comprises means for preventing or reducing the adhesion of biological material.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: January 25, 2022
    Assignee: ERBE ELEKTROMEDIZIN GMBH
    Inventors: Klaus Fischer, Mara Szyrach, Markus Enderle
  • Patent number: 11052257
    Abstract: A two-part NMS-test bench is provided with which instruments, generator voltages, and surgery modes can be evaluated with regard to neuromuscular stimulations. By separating the NMS-test bench in a first part for application of the instrument and in the second part for evaluation of the physiological effect on nerves, a measurement free of artifacts is possible. The spatial and timely separation of the RF-application from the recording of the compound action potentials makes RF-disturbances ineffective. The electrical signals gained in the instrument test chamber can be pre-processed. The recorded electrical signals emitted from the instrument can be evaluated at the nerve model an arbitrary number of times. The variance involved with the recording of compound action potentials during direct use of the instrument can thus be minimized. The separated test of the signals at the nerve model avoids thermal damage of a prepared nerve and falsification of measurement results.
    Type: Grant
    Filed: May 26, 2020
    Date of Patent: July 6, 2021
    Assignee: Erbe Elektromedizin GmbH
    Inventors: Markus Enderle, Ulrich Biber, Ovidiu Jurjut
  • Publication number: 20210169548
    Abstract: An instrument for thermal treatment of tissue (34), particularly for electrosurgical treatment and particularly for argon plasma coagulation, is disclosed. The instrument has an instrument body (25) extending between a proximal end (27) and a distal end (28). In an end section (38) adjoining a distal end (28) the instrument body (25) comprises at least one color mark (39) in a defined color. This color corresponds to the color of a treated tissue (34) that is created, if the dosage of an energy introduction for achieving a desired depth effect in the tissue (34) has been selected correctly. Preferably the instrument is configured as probe (17), particularly as endoscope probe and has a flexible bendable instrument body (25) that can be referenced as instrument hose (26).
    Type: Application
    Filed: December 4, 2020
    Publication date: June 10, 2021
    Inventors: Sandra Keller, Markus Enderle, Michael Ederer
  • Publication number: 20200376283
    Abstract: A two-part NMS-test bench is provided with which instruments, generator voltages, and surgery modes can be evaluated with regard to neuromuscular stimulations. By separating the NMS-test bench in a first part for application of the instrument and in the second part for evaluation of the physiological effect on nerves, a measurement free of artifacts is possible. The spatial and timely separation of the RF-application from the recording of the compound action potentials makes RF-disturbances ineffective. The electrical signals gained in the instrument test chamber can be pre-processed. The recorded electrical signals emitted from the instrument can be evaluated at the nerve model an arbitrary number of times. The variance involved with the recording of compound action potentials during direct use of the instrument can thus be minimized. The separated test of the signals at the nerve model avoids thermal damage of a prepared nerve and falsification of measurement results.
    Type: Application
    Filed: May 26, 2020
    Publication date: December 3, 2020
    Inventors: Markus Enderle, Ulrich Biber, Ovidiu Jurjut
  • Publication number: 20200306450
    Abstract: An instrument with a first conduit for emitting a first fluid from a first opening of the first conduit in an axial direction into a reacceleration zone and with a second conduit for channeling of a second fluid in the reacceleration zone in axial direction is provided such that active ingredient components, e.g. cells, of the second fluid are reaccelerated in axial direction as a result of the flow in the reacceleration zone by means of the first fluid that enters the reacceleration zone. A coaxial configuration of the first and the second conduit is preferred, because in doing so, around the first opening a shell jet of second fluid can be created that flows downstream in axial direction around the central working jet. In addition, a head for an inventive instrument and an application system with an inventive instrument is provided.
    Type: Application
    Filed: March 27, 2020
    Publication date: October 1, 2020
    Applicant: Erbe Elektromedizin GmbH
    Inventors: Markus Enderle, Andreas Fech, Achim Brodbeck
  • Publication number: 20200188009
    Abstract: A method for the selective elevation and separation of tissues comprised of multiple layers and a surgical instrument for performing the method. The method may be performed without the requirement of a solid mechanical device insertion or transection through the mucosal layer. In particular, the method and surgical instrument may be used for the selected separation and/or resection of selected portions of benign or malignant tissues (e.g. defining tissue planes, polyp elevation and removal, submucosal tissue tunnelling, endoscopic mucosa resection, etc).
    Type: Application
    Filed: February 21, 2020
    Publication date: June 18, 2020
    Inventors: Klaus Fischer, Dan Maurice, John Day, Markus Enderle
  • Publication number: 20200129700
    Abstract: The invention relates to an instrument head, comprising: an exit opening (23); a first feed line (11) for the feed of a first fluid; a second feed line (12) for the feed of a second fluid; a reservoir (24) for storing the fluid fed via the second feed line (12); wherein the reservoir (24) is in fluid communication with the first feed line (11) and/or is adapted to be brought in fluid communication with the first feed line (11) via at least a valve (25) arranged in the instrument head, to deliver fluid stored in the reservoir (24) via the exit opening (23).
    Type: Application
    Filed: December 30, 2019
    Publication date: April 30, 2020
    Inventors: Andreas Fech, Klaus Fischer, Lars Blobel, Waldemar Wandel, Markus Enderle
  • Patent number: 10624689
    Abstract: The ablation device (11) according to the invention is distinguished by a head (20) having a noncircular cross-section and by electrodes (32, 33) being positioned at an acute angle relative to each other. Due to the angular arrangement of the electrodes and the appropriate configuration of the channels (28, 29), there results an approximately fan-shaped plasma beam with which—in particular with the alternating activation of the two electrodes—a wide strip-shaped ablation region can be achieved on hollow organs of living beings. Handling is reliable and simplified, and, compared to existing measures, the treatment time is reduced.
    Type: Grant
    Filed: September 9, 2016
    Date of Patent: April 21, 2020
    Assignee: Erbe Elektromedizin GmbH
    Inventors: Markus Enderle, Klaus Fischer, Thomas Stäbler
  • Patent number: 10603095
    Abstract: A method for the selective elevation and separation of tissues comprised of multiple layers and a surgical instrument for performing the method. The method may be performed without the requirement of a solid mechanical device insertion or transection through the mucosal layer. In particular, the method and surgical instrument may be used for the selected separation and/or resection of selected portions of benign or malignant tissues (e.g. defining tissue planes, polyp elevation and removal, submucosal tissue tunnelling, endoscopic mucosa resection, etc).
    Type: Grant
    Filed: February 2, 2017
    Date of Patent: March 31, 2020
    Assignee: Erbe Elektromedizin GmbH
    Inventors: Klaus Fischer, Dan Maurice, John Day, Markus Enderle
  • Publication number: 20200093999
    Abstract: A medical instrument with an aerosol outlet, which is fluidically connected—via an aerosol line—to a generation device. The generation device is adapted to generate aerosol for dispensing by means of the medical instrument. In addition, a generation device is stated, which, in embodiments of the generation device, for example can be used in a device with the instrument according to the invention. The generation device comprises a mixing unit for mixing a liquid and a gas together, which mixing unit is connected to a liquid container for supplying the mixing unit with a liquid, in which case the generation device is adapted to utilize the gas pressure of a gas under pressure subjecting the liquid to a pressure in order to press the liquid out of the liquid container to the mixing unit.
    Type: Application
    Filed: September 25, 2019
    Publication date: March 26, 2020
    Inventors: Alexander Neagos, Markus Enderle, Christian Schaefer
  • Publication number: 20200093537
    Abstract: A preparation instrument comprising an HF-instrument with an electrode that is partially insulated by means of an insulating body, which is combined with a fluid applicator having a channel arranged in the insulating body for the application of a fluid to or into tissue. In some embodiments of the preparation instrument, the electrode is a spatula electrode which is inserted in the insulating body that does not cover sections of the surface of the electrode so that these sections may be in contact with the tissue. The insulating body preferably forms the channel wall that delimits the channel. The insulating body and the electrode may be flexible in order to adapt the form of the insulating body and the electrode, together, to the surgical task.
    Type: Application
    Filed: September 20, 2019
    Publication date: March 26, 2020
    Inventors: Klaus Fischer, Markus Enderle, Achim Brodbeck, Alexander Neagos, Andreas Fech
  • Patent number: 10589299
    Abstract: The invention relates to a method for mixing at least two fluids using an externally mixing nozzle for medical purposes, which has at least two outlet channels (10, 20) and at least two inlet openings (13, 23) with different or identical cross-sections, wherein two fluids with different volumetric flows and/or different viscosity are sprayed, and wherein the ratio of the cross-sections of the inlet channels (13, 23) and/or the outlet channels (10, 20) corresponds to the ratio of the volumetric flows so that the fluids flow with substantially identical flow speeds through the outlet channels (10, 20) and/or the inlet openings (13, 23). The invention furthermore relates to an externally mixing nozzle, a medical instrument and a medical device for spraying substances, in particular biological material.
    Type: Grant
    Filed: February 16, 2015
    Date of Patent: March 17, 2020
    Assignee: Erbe Elektromedizin GmbH
    Inventors: Andreas Fech, Klaus Fischer, Markus Enderle
  • Patent number: 10575891
    Abstract: The ablation system (10) according to the invention works with an ablation probe (12, 12a) that comprises two alternatingly working spark plasma electrodes (31, 32). They generate a plasma beam (47, 48) having a non-circular cross-section, which beam is to be guided—transversely with respect to the large longitudinal axis of its preferably oval cross-section—over the tissue to be ablated, in particular the mucosa (14). In doing so, it is possible to treat large-area tissue regions by means of a reliable and easily controllable procedure.
    Type: Grant
    Filed: September 8, 2016
    Date of Patent: March 3, 2020
    Assignee: Erbe Elektromedizin GmbH
    Inventors: Markus Enderle, Klaus Fischer, Thomas Stäbler
  • Patent number: 10569022
    Abstract: The invention relates to a supply system having at least one outlet for connecting to an applicator instrument, and having a controller (51) that controls at least one valve (50, 50?, 50?, 50??) such that, within an application time interval of less than 4 s, in particular less than 2 s: a) a first fluid during at least a first delivery interval (T1) with a first pressure (ph) is conveyed in a first feed line (11); b) a second fluid during a second delivery interval (T2) following the first conveying interval (T1) is conveyed with a second pressure (pz) in a second feed line (23); and c) the first fluid, during at least a third delivery interval (T3), is conveyed with a third pressure (pl) in the first feed line (11).
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: February 25, 2020
    Assignee: Erbe Elektromedizin GmbH
    Inventors: Andreas Fech, Klaus Fischer, Lars Blobel, Waldemar Wandel, Markus Enderle
  • Patent number: 10549041
    Abstract: The invention relates to an instrument head, comprising: an exit opening (23); a first feed line (11) for the feed of a first fluid; a second feed line (12) for the feed of a second fluid; a reservoir (24) for storing the fluid fed via the second feed line (12); wherein the reservoir (24) is in fluid communication with the first feed line (11) and/or is adapted to be brought in fluid communication with the first feed line (11) via at least a valve (25) arranged in the instrument head, to deliver fluid stored in the reservoir (24) via the exit opening (23).
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: February 4, 2020
    Assignee: Erbe Elektromedizin GmbH
    Inventors: Andreas Fech, Klaus Fischer, Lars Blobel, Waldemar Wandel, Markus Enderle
  • Publication number: 20190090752
    Abstract: The instrument according to the invention for electrosurgically impacting biological tissue comprises an electrode (18) as well as a light guide (21), which is connected to a light inlet window (19), which is formed by means of a fluid body (27). The light guide is connected to a light analysis device (13), so as to absorb the light, which is generated at the electrode (18) in response to the HF surgery and so as to supply it to the light analysis device (13). The light inlet window (19) is arranged at the point of origin of the light, namely immediately at the electrode, that is, at the spark, which is generated. An adulteration of the absorbed light by means of smoke or particle deposition on the light inlet window (19) can virtually be avoided.
    Type: Application
    Filed: November 26, 2018
    Publication date: March 28, 2019
    Inventors: Klaus Fischer, Alexander Neugebauer, Dominik Spether, Markus Enderle