Patents by Inventor Markus Essler

Markus Essler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Radiolabelled antibody and uses thereof
    Patent number: 9486547
    Abstract: The present disclosure describes a radioconjugate of an anti-CD38 antibody and a radionuclide, e.g., Bi213.
    Type: Grant
    Filed: November 4, 2013
    Date of Patent: November 8, 2016
    Assignee: MORPHOSYS AG
    Inventor: Markus Essler
  • Radiolabelled Antibody And Uses Thereof
    Publication number: 20150283275
    Abstract: The present disclosure describes a radioconjugate of an anti-CD38 antibody and a radionuclide, e.g., Bi213.
    Type: Application
    Filed: November 4, 2013
    Publication date: October 8, 2015
    Inventor: Markus Essler
  • Breast homing peptides and methods of identifying same using aminopeptidase P
    Patent number: 7666391
    Abstract: The present invention provides a method of directing a moiety to breast vasculature in a subject by administering to the subject a conjugate which contains a moiety linked to a homing molecule that selectively homes to breast vasculature, whereby the moiety is directed to breast vasculature. In one embodiment, the homing molecule is a peptide containing the amino acid sequence PGPEGAG (SEQ ID NO: 1), or a peptidomimetic thereof.
    Type: Grant
    Filed: May 29, 2002
    Date of Patent: February 23, 2010
    Assignee: Burnham Institute for Medical Research
    Inventors: Erkki Ruoslahti, Markus Essler
  • Collagen-binding molecules that selectively home to tumor vasculature and methods of using same
    Patent number: 7488792
    Abstract: The present invention provides a conjugate containing a therapeutic agent linked to a homing molecule that selectively homes to tumor vasculature and selectively binds collagen such as non-helical collagen or collagen IV. In one embodiment, the conjugate contains a homing peptide or peptidomimetic that includes the amino acid sequence CREKA (SEQ ID NO: 1) or a conservative variant or peptidomimetic thereof.
    Type: Grant
    Filed: August 25, 2003
    Date of Patent: February 10, 2009
    Assignee: Burnham Institute for Medical Research
    Inventors: Erkki Ruoslahti, Markus Essler, Darren M. Brown
  • Collagen-binding molecules that selectively home to tumor vasculature and methods of using same
    Publication number: 20050048063
    Abstract: The present invention provides a conjugate containing a therapeutic agent linked to a homing molecule that selectively homes to tumor vasculature and selectively binds collagen such as non-helical collagen or collagen IV. In one embodiment, the conjugate contains a homing peptide or peptidomimetic that includes the amino acid sequence CREKA (SEQ ID NO: 1) or a conservative variant or peptidomimetic thereof.
    Type: Application
    Filed: August 25, 2003
    Publication date: March 3, 2005
    Inventors: Erkki Ruoslahti, Markus Essler, Darren Brown
  • Breast homing peptides and methods of identifying same using aminopeptidase P
    Publication number: 20030232762
    Abstract: The present invention provides a method of directing a moiety to breast vasculature in a subject by administering to the subject a conjugate which contains a moiety linked to a homing molecule that selectively homes to breast vasculature, whereby the moiety is directed to breast vasculature. In one embodiment, the homing molecule is a peptide containing the amino acid sequence PGPEGAG (SEQ ID NO: 1), or a peptidomimetic thereof.
    Type: Application
    Filed: May 29, 2002
    Publication date: December 18, 2003
    Inventors: Erkki Ruoslahti, Markus Essler