Patents by Inventor Markus Herrgard

Markus Herrgard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mass spectrometry method
    Patent number: 8871525
    Abstract: The invention provides a mechanism for semi-quantitatively measuring individual isotopomer species of a molecule using gas chromatograph mass spectrometry. The method allows for semi-quantitatively tracking the movement of ions by measuring the individual isotopomer species of a molecule.
    Type: Grant
    Filed: September 30, 2011
    Date of Patent: October 28, 2014
    Assignee: Synthetic Genomics, Inc.
    Inventors: Kevin Martin, Markus Herrgard, Kathleen Reeves
  • MASS SPECTROMETRY METHOD
    Publication number: 20120083041
    Abstract: The invention provides a mechanism for semi-quantitatively measuring individual isotopomer species of a molecule using gas chromatograph mass spectrometry. The method allows for semi-quantitatively tracking the movement of ions by measuring the individual isotopomer species of a molecule.
    Type: Application
    Filed: September 30, 2011
    Publication date: April 5, 2012
    Applicant: SYNTHETIC GENOMICS, INC.
    Inventors: Kevin Martin, Markus Herrgard, Kathleen Reeves
  • Methods and systems to identify operational reaction pathways
    Patent number: 7869957
    Abstract: The present invention provides a method of refining a biosystem reaction network. The method consists of: (a) providing a mathematical representation of a biosystem; (b) reconciling said mathematical representation of said biosystem; (c) determining differences between observed behavior of a biosystem and in silico behavior of said mathematical representation of said biosystem under similar conditions; (d) modifying a structure of said mathematical representation of said biosystem, and (e) determining differences between said observed behavior of said biosystem and in silico behavior of said modified mathematical representation of said biosystem under similar conditions.
    Type: Grant
    Filed: April 27, 2004
    Date of Patent: January 11, 2011
    Assignee: The Regents of the University of California
    Inventors: Bernhard O. Palsson, Markus W. Covert, Markus Herrgard
  • Methods and Systems to Identify Operational Reaction Pathways
    Publication number: 20100317007
    Abstract: The present invention provides a method for identifying an operational reaction pathway of a biosystem. The method includes (a) providing a set of systemic reaction pathways through a reaction network representing said biosystem; (b) providing a set of phenomenological reaction pathways of said biosystem, and (c) comparing said set of systemic reaction pathways with said set of phenomenological reaction pathways, wherein a pathway common to said sets is an operational reaction pathway of said biosystem. Also described is a method of refining a biosystem reaction network; a method of reconciling biosystem data sets; a method of determining the effect of a genetic polymorphism on whole cell function; and a method of diagnosing a genetic polymorphism-mediated pathology.
    Type: Application
    Filed: May 27, 2010
    Publication date: December 16, 2010
    Inventors: Bernard O. Palsson, Markus W. Covert, Markus Herrgard
  • Methods and systems to identify operational reaction pathways
    Patent number: 7734420
    Abstract: The present invention provides a method for identifying an operational reaction pathway of a biosystem. The method includes (a) providing a set of systemic reaction pathways through a reaction network representing said biosystem; (b) providing a set of phenomenological reaction pathways of said biosystem, and (c) comparing said set of systemic reaction pathways with said set of phenomenological reaction pathways, wherein a pathway common to said sets is an perational reaction pathway of said biosystem. Also described is a method of refining a biosystem reaction network; a method of reconciling biosystem data sets; a method of determining the effect of a genetic polymorphism on whole cell function; and a method of diagnosing a genetic polymorphism-mediated pathology.
    Type: Grant
    Filed: February 14, 2003
    Date of Patent: June 8, 2010
    Assignee: The Regents of the University of California
    Inventors: Bernhard O. Palsson, Markus W. Covert, Markus Herrgard
  • Methods and systems to identify operational reaction pathways
    Publication number: 20040210398
    Abstract: The present invention provides a method of refining a biosystem reaction network. The method consists of: (a) providing a mathematical representation of a biosystem; (b) reconciling said mathematical representation of said biosystem; (c) determining differences between observed behavior of a biosystem and in silico behavior of said mathematical representation of said biosystem under similar conditions; (d) modifying a structure of said mathematical representation of said biosystem, and (e) determining differences between said observed behavior of said biosystem and in silico behavior of said modified mathematical representation of said biosystem under similar conditions.
    Type: Application
    Filed: April 27, 2004
    Publication date: October 21, 2004
    Applicant: The Regents of the University of California
    Inventors: Bernhard O. Palsson, Markus W. Covert, Markus Herrgard
  • Methods and systems to identify operational reaction pathways
    Publication number: 20040072723
    Abstract: The present invention provides a method for identifying an operational reaction pathway of a biosystem. The method includes (a) providing a set of systemic reaction pathways through a reaction network representing said biosystem; (b) providing a set of phenomenological reaction pathways of said biosystem, and (c) comparing said set of systemic reaction pathways with said set of phenomenological reaction pathways, wherein a pathway common to said sets is an perational reaction pathway of said biosystem. Also described is a method of refining a biosystem reaction network; a method of reconciling biosystem data sets; a method of determining the effect of a genetic polymorphism on whole cell function; and a method of diagnosing a genetic polymorphism-mediated pathology.
    Type: Application
    Filed: February 14, 2003
    Publication date: April 15, 2004
    Inventors: Bernhard O. Palsson, Markus W. Covert, Markus Herrgard