Abstract: The present invention relates to a bispecific antibody construct comprising a first binding domain which binds to human EGFRVIII on the surface of a target cell and a second binding domain which binds to human CD3 on the surface of a T cell. Moreover, the invention provides a polynucleotide encoding the antibody construct, a vector comprising said polynucleotide and a host cell transformed or transfected with said polynucleotide or vector. Furthermore, the invention provides a process for the production of the antibody construct of the invention, a medical use of said antibody construct and a kit comprising said antibody construct.

Abstract: A support rod for a vehicle seat head restraint, which is formed as a tube, having at least one structure as part of a locking device and intended for cooperating with a catch of the locking device which is associated with a holding structure. The structure has a base surface which prevents movement of the catch radially to a central axis of the support rod and includes a catch surface that prevents, together with the catch, movement of the support rod in a first direction. At least one catch structure as a detent structure has a cut-out tongue. An inner surface of the tongue radially facing a central axis of the support rod at a free end being spaced apart from the base surface by a height so that the catch is movable at least with a partial region radially under a region of the inner surface of the tongue.

Abstract: A motor vehicle including a latch and a pawl, the latch is adjustable between an open position and a locked position, the pawl is adjustable between a lowered position and a raised position, a drive arrangement which, in an opening movement, adjusts an adjusting arrangement such that the adjusting arrangement raises the pawl, an actuating lever and a clutch arrangement arranged between the actuating lever and the pawl, in the disengaging state, the actuating stroke of the actuating lever is an idle stroke with regard to the raising of the pawl and in the engaging state, the pawl is able to be raised via the actuating stroke of the actuating lever, the adjusting arrangement with the opening movement, shifts the clutch arrangement from the disengaging state to the engaging state. An unlocking movement shifts the clutch arrangement from the disengaging state into the engaging state via the adjusting arrangement.

Abstract: The invention relates to a dental composition provided as a kit of parts comprising a base paste and an initiator paste, the base paste comprising, a cationically curable pre-polymer comprising a backbone and at least two aziridine moieties, filler, the initiator paste comprising an initiator being able to start the hardening of the polyether pre-polymer, filler, optionally diluent, the base paste or the initiator paste or the base paste and the initiator paste comprising in addition an isosorbide component. The invention also relates to a process of taking an impression of dental tissue.

Abstract: The invention relates to a method for producing a plastic film from a total amount of raw materials using a film extrusion machine. According to the invention, the method comprises the following steps: detecting film parameters relating to desired properties of the plastic film, detecting raw material parameters relating to properties of the raw materials, grouping the raw material parameter into at least two raw material parameter groups, forming correlations between raw material parameter groups, forming correlations between film parameters and the raw material parameter groups based on a film production model, detecting a selection of at least one raw material from at least one raw material parameter group, calculating at least one production parameter of the film extrusion machine based on the film production model.

Abstract: The invention relates to a method for producing a film from a total quantity of raw materials using an extrusion machine, comprising the following steps: detecting machine parameters relating to properties and/or settings of at least one film extrusion machine, detecting film parameters relating to desired properties of the film, detecting raw material parameters relating to properties of the raw materials, inputting the detected parameters in a film production model, calculating a selection and/or an amount of raw materials from the total quantity of raw materials based on the detected parameters and the film production model, outputting information relating to the selection and/or the amount of raw materials.

Abstract: The invention relates to a method for producing a plastic film from a total quantity of raw materials in a film extrusion machine. Said method according to the invention comprises the following steps: providing a selection of raw materials from a total quantity of raw materials, setting machine and production parameters of the film extrusion machine, supplying the selection of raw materials to the film extrusion machine in a composition, detecting at least one actual value of a property of the plastic film, forming a difference between the actual value and a target value of the property, changing the selection of raw materials and/or the composition of the raw materials, if the difference exceeds a threshold.

Abstract: A method for the semi-automated assembly of a headrest for a vehicle seat, including the following method steps: feeding a cover stretched in a holder of the headrest to a conveying device, which cover includes an opening, such that an edge region of the opening is held open by the holder in such a way that a head box can be inserted into an inner space of the cover; transporting the holder in the conveying device to at least one workstation; feeding and mounting of an upholstered part; orienting seam edges of the cover; automatic assembly of a head box assembly in an inner space of the pocket-like cover; closing the opening of the cover; removing the headrest from the holder; removing the holder from the conveying device; and performing an ironing process.

Abstract: The present embodiments relate to an antifouling polymer comprising a plurality of repeating units. At least a portion of the plurality of repeating units comprises medetomidine, or an enantiomer, base or salt thereof, covalently bound to the repeating unit through a hydrolysable bond. The antifouling polymer can comprised in an antifouling composition applied as a surface coating on underwater or submersible structures to prevent or at least inhibit marine biofouling on surfaces of the structures.

Abstract: A method for operating a brake system of a vehicle in a maintenance mode and in a normal mode includes providing a brake pressure in the brake system in the normal mode using a brake pressure generator. The method further includes preventing a provision of a brake pressure by the brake pressure generator in the maintenance mode.

Abstract: The invention relates to a method of manufacturing components, comprising the steps of: a) manufacturing a component blank in an additive manufacturing process, comprising: a1) determining component regions of the component blank to be cured in an electronic planning process and generating a component blank data set defining the component regions to be cured, a2) arranging a raw material and selectively curing and joining the raw material in the component regions to be cured on the basis of the component blank data set to form the component blank, wherein the curing and joining of the raw material on the basis of the component blank data set is carried out such, that the component blank has a component blank density which is less than 99.

Abstract: A support rod for a vehicle seat head restraint, which is formed as a tube, having at least one structure as part of a locking device and intended for cooperating with a catch of the locking device which is associated with a holding structure. The structure has a base surface which prevents movement of the catch radially to a central axis of the support rod and includes a catch surface that prevents, together with the catch, movement of the support rod in a first direction. At least one catch structure as a detent structure has a cut-out tongue. An inner surface of the tongue radially facing a central axis of the support rod at a free end being spaced apart from the base surface by a height so that the catch is movable at least with a partial region radially under a region of the inner surface of the tongue.

Abstract: An arrangement with operator servers and operator clients, wherein process image modules associated with process objects and having tags are stored in the operator servers, where the operator server functions as a local server and the other operator server functions as a remote server, the local server receives the tags stored in the remote servers, where each operator client registers with one of the operator servers to establish a client-server connection, and is also configured to display a system image with block symbols associated with the process objects, and where the local server transmits the process data of the local and the process data of the remote server to the registered operator client via the client-server connection in order to update the block symbols of the system image such that, within the scope of updating a system image, an operator is referred to the communication load between the operator servers.

Abstract: A method for operating a brake system of a vehicle in a maintenance mode and in a normal mode includes providing a brake pressure in the brake system in the normal mode using a brake pressure generator. The method further includes preventing a provision of a brake pressure by the brake pressure generator in the maintenance mode.

Abstract: An arrangement with operator servers and operator clients, wherein process image modules associated with process objects and having tags are stored in the operator servers, where the operator server functions as a local server and the other operator server functions as a remote server, the local server receives the tags stored in the remote servers, where each operator client registers with one of the operator servers to establish a client-server connection, and is also configured to display a system image with block symbols associated with the process objects, and where the local server transmits the process data of the local and the process data of the remote server to the registered operator client via the client-server connection in order to update the block symbols of the system image such that, within the scope of updating a system image, an operator is referred to the communication load between the operator servers.

Abstract: The invention relates to a headrest for a seat, in particular for a vehicle seat, having a base (11) mounted on at least one support post (12a, 12b) on the seat and displaceable relative to the support post, having a latch (16) moveable between a locking position and a release position and capable of locking the base in at least one position relative to the support post, the latch comprising first holding means (46) on the base (11) and second holding means (47) on the support post (12a, 12b), the first holding means being formed on a slide (19) moveably mounted on the base (11) such that the first holding means and the second holding means are in engagement in the locking position and are in disengagement in the release position.

Abstract: The invention relates to a headrest for a seat, in particular for a vehicle seat, having a base (11) mounted on at least one support post (12a, 12b) on the seat and displaceable relative to the support post, having a latch (16) moveable between a locking position and a release position and capable of locking the base in at least one position relative to the support post, the latch comprising first holding means (46) on the base (11) and second holding means (47) on the support post (12a, 12b), the first holding means being formed on a slide (19) moveably mounted on the base (11) such that the first holding means and the second holding means are in engagement in the locking position and are in disengagement in the release position.

Abstract: A support tube adapted to carry a motor-vehicle accessory and to slide in a bearing tube provided with a latch element is hollow, cylindrical, centered on an axis, and formed with a plurality of outwardly open notches. These notches are each in turned formed by a flat latch face extending generally perpendicular to the axis, an outwardly open indent adjacent the latch face, a cam face extending from the latch radially outward to an outer surface of the tube, and a flat base face extending generally parallel to the axis from an inner edge of the latch face to an inner edge of the cam face.

Abstract: A lamp has an LED, a base, and a reflector. The base is rigidly connected to the LED and has a base contact surface. The reflector, which can be connected to the base, has a reflector contact surface, an entry opening, an exit opening, and a longitudinal direction (L) that runs from the exit opening to the entry opening. The reflector contact surface is arranged in the longitudinal direction (L) between the entry opening and the exit opening, and the base contact surface abuts the reflector contact surface. Thus, movement of the base and/or reflector towards each other is prevented when the reflector is connected to the base. The reflector is formed in such a way that a projection of the reflector contact surface in the longitudinal direction (L) of the reflector is free of undercuts.

Abstract: The present invention relates to compounds of the general formula I in which the variables are each defined as follows: W is a (Y4-T2-)s(Y3-A2-)tY2—Z2 moiety, Z1, Z2 are each independently unreactive radicals as defined more specifically in the description or reactive radicals through which polymerization can be brought about, A1, A2 are each independently spacers as defined more specifically in the description, Y1 to Y5 are linking units as defined more specifically in the description, Y6 is a chemical single bond or —CO—, T1, T2 are each independently, as defined more specifically in the description, divalent saturated or unsaturated, optionally substituted and optionally fused iso- or heterocyclic radicals, Q is substituents as defined more specifically in the description, r, t are each independently 0 or 1, s is 0, 1, 2 or 3 and q is 0, 1, 2, 3 or 4.