Patents by Inventor Markus Junker

Markus Junker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12146510
    Abstract: A hydrostatic cylinder with a gas pressure accumulator, which is preferably designed as a piston accumulator, and which is arranged concentrically on the outer circumference of the cylinder is disclosed. A gas pressure is produced via a constant pressure source and is limited or is essentially constant in the gas pressure accumulator and also a constant pressure medium pressure is independent of the degree of filling of the gas pressure accumulator.
    Type: Grant
    Filed: October 20, 2020
    Date of Patent: November 19, 2024
    Assignee: Robert Bosch GmbH
    Inventors: Marc Weigand, Markus Junker
  • Publication number: 20240239882
    Abstract: The present invention relates to novel monoclonal anti-human-GDF-15 antibodies, pharmaceutical compositions, kits, methods and uses and the cell lines capable of producing the monoclonal antibodies described herein. The present invention further relates to novel antibodies to human GDF-15 capable of inhibiting cancer growth.
    Type: Application
    Filed: December 21, 2023
    Publication date: July 18, 2024
    Inventors: Jörg WISCHHUSEN, Markus JUNKER, Thomas MÜLLER, Stefan SAREMBA
  • Patent number: 11891436
    Abstract: The present invention relates to novel monoclonal anti-human-GDF-15 antibodies, pharmaceutical compositions, kits, methods and uses and the cell lines capable of producing the monoclonal antibodies described herein. The present invention further relates to novel antibodies to human GDF-15 capable of inhibiting cancer growth.
    Type: Grant
    Filed: August 11, 2020
    Date of Patent: February 6, 2024
    Assignee: JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG
    Inventors: Jörg Wischhusen, Markus Junker, Thomas Müller, Stefan Saremba
  • Patent number: 11873848
    Abstract: A hydraulic control block for controlling a supply of pressurizing medium to an electrohydraulic or servo hydraulic axle includes a plurality of internally situated hydraulic interfaces configured to fluidically connect at least one of a source of pressurizing medium and a pressurizing medium sink of the axle to any hydraulic cylinder selected from a group of hydraulic cylinders of different structural forms, wherein the internally situated hydraulic interfaces are configured to selectively supply pressurizing medium to the selected hydraulic cylinder. The control block further includes an insert part configured as a function of the structural form of the selected hydraulic cylinder such that each of the plurality of internally situated hydraulic interfaces is one of tapped and blocked for the purpose of the fluidic connection.
    Type: Grant
    Filed: June 19, 2020
    Date of Patent: January 16, 2024
    Assignee: Robert Bosch GmbH
    Inventors: Markus Junker, Manuel Rumpel
  • Publication number: 20230382987
    Abstract: The present invention relates to monoclonal anti-human-GDF-15 antibodies. The antibodies include chimeric antibodies and humanized antibodies. The invention also relates to monoclonal anti-human-GDF-15 antibodies including murine antibodies, chimeric antibodies and humanized antibodies for use in methods for the treatment of cancer cachexia and also for the treatment of cancer. The invention also provides pharmaceutical compositions, kits, methods and uses and cell lines capable of producing the monoclonal antibodies of the invention.
    Type: Application
    Filed: August 2, 2023
    Publication date: November 30, 2023
    Inventors: Jörg WISCHHUSEN, Markus JUNKER, Tina SCHÄFER, Dirk PÜHRINGER
  • Patent number: 11760795
    Abstract: The present invention relates to monoclonal anti-human-GDF-15 antibodies. The antibodies include chimeric antibodies and humanized antibodies. The invention also relates to monoclonal anti-human-GDF-15 antibodies including murine anti bodies, chimeric antibodies and humanized antibodies for use in methods for the treatment of cancer cachexia and also for the treatment of cancer. The invention also provides pharmaceutical compositions, kits, methods and uses and cell lines capable of producing the monoclonal antibodies of the invention.
    Type: Grant
    Filed: February 19, 2020
    Date of Patent: September 19, 2023
    Assignee: JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG
    Inventors: Jörg Wischhusen, Markus Junker, Tina Schäfer, Dirk Pühringer
  • Patent number: 11634482
    Abstract: The present invention relates to monoclonal anti-human-GDF-15 antibodies. The antibodies include chimeric anti-bodies and humanized antibodies. The invention also relates to monoclonal anti-human-GDF-15 antibodies including murine anti-bodies, chimeric antibodies and humanized antibodies for use in methods for the treatment of cancer cachexia and also for the treatment of cancer. The invention also provides pharmaceutical compositions, kits, methods and uses and cell lines capable of producing the monoclonal antibodies of the invention.
    Type: Grant
    Filed: February 19, 2020
    Date of Patent: April 25, 2023
    Assignee: Julius-Maxmilians-Universitat Wurzburg
    Inventors: Jörg Wischhusen, Markus Junker, Tina Schäfer, Dirk Pühringer
  • Publication number: 20230018337
    Abstract: A method for producing a diaphragm for an ultrasonic sensor. In the method, a diaphragm body made of metal material is first provided. Next, an external surface region of the diaphragm body is degreased. The external surface region of the diaphragm body is then pickled. To pre-activate the subsequently applied second passivation layer, a first passivation layer is also deposited on the external surface region as a first layer.
    Type: Application
    Filed: November 18, 2020
    Publication date: January 19, 2023
    Inventors: Eva-Maria Neugebauer, Tobias Liebelt, Stefanie Boetticher, Markus Junker
  • Publication number: 20220397127
    Abstract: A hydrostatic cylinder with a gas pressure accumulator, which is preferably designed as a piston accumulator, and which is arranged concentrically on the outer circumference of the cylinder is disclosed. A gas pressure is produced via a constant pressure source and is limited or is essentially constant in the gas pressure accumulator and also a constant pressure medium pressure is independent of the degree of filling of the gas pressure accumulator.
    Type: Application
    Filed: October 20, 2020
    Publication date: December 15, 2022
    Inventors: Marc Weigand, Markus Junker
  • Publication number: 20220381269
    Abstract: A hydraulic control block for controlling a supply of pressurizing medium to an electrohydraulic or servo hydraulic axle includes a plurality of internally situated hydraulic interfaces configured to fluidically connect at least one of a source of pressurizing medium and a pressurizing medium sink of the axle to any hydraulic cylinder selected from a group of hydraulic cylinders of different structural forms, wherein the internally situated hydraulic interfaces are configured to selectively supply pressurizing medium to the selected hydraulic cylinder. The control block further includes an insert part configured as a function of the structural form of the selected hydraulic cylinder such that each of the plurality of internally situated hydraulic interfaces is one of tapped and blocked for the purpose of the fluidic connection.
    Type: Application
    Filed: June 19, 2020
    Publication date: December 1, 2022
    Inventors: Markus Junker, Manuel Rumpel
  • Patent number: 11085466
    Abstract: An electrohydraulic system for use under water includes an electrohydraulic actuator and a container having an internal space provided for forming a volume which is enclosed from the environment and which is provided for receiving a hydraulic pressurized fluid. A hydraulic cylinder is provided in the internal space of the container, the inside of which is divided into a first cylinder chamber and a second cylinder chamber by a piston to which a first piston rod and a second piston rod are connected. The two active surfaces of the piston are the same or approximately the same size.
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: August 10, 2021
    Assignee: Robert Bosch GmbH
    Inventors: Alexandre Orth, Gottfried Hendrix, Markus Junker
  • Publication number: 20210054060
    Abstract: The present invention relates to novel monoclonal anti-human-GDF-15 antibodies, pharmaceutical compositions, kits, methods and uses and the cell lines capable of producing the monoclonal antibodies described herein. The present invention further relates to novel antibodies to human GDF-15 capable of inhibiting cancer growth.
    Type: Application
    Filed: August 11, 2020
    Publication date: February 25, 2021
    Inventors: Jörg WISCHHUSEN, Markus JUNKER, Thomas MÜLLER, Stefan SAREMBA
  • Publication number: 20200308265
    Abstract: The present invention relates to monoclonal anti-human-GDF-15 antibodies. The antibodies include chimeric antibodies and humanized antibodies. The invention also relates to monoclonal anti-human-GDF-15 antibodies including murine anti bodies, chimeric antibodies and humanized antibodies for use in methods for the treatment of cancer cachexia and also for the treatment of cancer. The invention also provides pharmaceutical compositions, kits, methods and uses and cell lines capable of producing the monoclonal antibodies of the invention.
    Type: Application
    Filed: February 19, 2020
    Publication date: October 1, 2020
    Inventors: Jörg WISCHHUSEN, Markus JUNKER, Tina SCHÄFER, Dirk PÜHRINGER
  • Publication number: 20200308264
    Abstract: The present invention relates to monoclonal anti-human-GDF-15 antibodies. The antibodies include chimeric anti-bodies and humanized antibodies. The invention also relates to monoclonal anti-human-GDF-15 antibodies including murine anti-bodies, chimeric antibodies and humanized antibodies for use in methods for the treatment of cancer cachexia and also for the treatment of cancer. The invention also provides pharmaceutical compositions, kits, methods and uses and cell lines capable of producing the monoclonal antibodies of the invention.
    Type: Application
    Filed: February 19, 2020
    Publication date: October 1, 2020
    Inventors: Jörg WISCHHUSEN, Markus JUNKER, Tina SCHÄFER, Dirk PÜHRINGER
  • Patent number: 10781251
    Abstract: The present invention relates to novel monoclonal anti-human-GDF-15 antibodies, pharmaceutical compositions, kits, methods and uses and the cell lines capable of producing the monoclonal antibodies described herein. The present invention further relates to novel antibodies to human GDF-15 capable of inhibiting cancer growth.
    Type: Grant
    Filed: March 12, 2018
    Date of Patent: September 22, 2020
    Assignee: JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG
    Inventors: Jörg Wischhusen, Markus Junker, Thomas Müller, Stefan Saremba
  • Publication number: 20200158140
    Abstract: An electrohydraulic system for use under water includes an electrohydraulic actuator and a container having an internal space provided for forming a volume which is enclosed from the environment and which is provided for receiving a hydraulic pressurized fluid. A hydraulic cylinder is provided in the internal space of the container, the inside of which is divided into a first cylinder chamber and a second cylinder chamber by a piston to which a first piston rod and a second piston rod are connected. The two active surfaces of the piston are the same or approximately the same size.
    Type: Application
    Filed: March 26, 2018
    Publication date: May 21, 2020
    Inventors: Alexandre Orth, Gottfried Hendrix, Markus Junker
  • Patent number: 10604565
    Abstract: The present invention relates to monoclonal anti-human-GDF-15 antibodies. The antibodies include chimeric antibodies and humanized antibodies. The invention also relates to monoclonal anti-human-GDF-15 antibodies including murine antibodies, chimeric antibodies and humanized antibodies for use in methods for the treatment of cancer cachexia and also for the treatment of cancer. The invention also provides pharmaceutical compositions, kits, methods and uses and cell lines capable of producing the monoclonal antibodies of the invention.
    Type: Grant
    Filed: March 5, 2018
    Date of Patent: March 31, 2020
    Assignee: JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG
    Inventors: Jörg Wischhusen, Markus Junker, Tina Schäfer, Dirk Pühringer
  • Publication number: 20180305447
    Abstract: The present invention relates to novel monoclonal anti-human-GDF-15 antibodies, pharmaceutical compositions, kits, methods and uses and the cell lines capable of producing the monoclonal antibodies described herein. The present invention further relates to novel antibodies to human GDF-15 capable of inhibiting cancer growth.
    Type: Application
    Filed: March 12, 2018
    Publication date: October 25, 2018
    Inventors: Jörg WISCHHUSEN, Markus JUNKER, Thomas MÜLLER, Stefan SAREMBA
  • Publication number: 20180298091
    Abstract: The present invention relates to monoclonal anti-human-GDF-15 antibodies. The antibodies include chimeric antibodies and humanized antibodies. The invention also relates to monoclonal anti-human-GDF-15 antibodies including murine antibodies, chimeric antibodies and humanized antibodies for use in methods for the treatment of cancer cachexia and also for the treatment of cancer. The invention also provides pharmaceutical compositions, kits, methods and uses and cell lines capable of producing the monoclonal antibodies of the invention.
    Type: Application
    Filed: March 5, 2018
    Publication date: October 18, 2018
    Inventors: Jörg WISCHHUSEN, Markus JUNKER, Tina SCHÄFER, Dirk PÜHRINGER
  • Publication number: 20170204174
    Abstract: The present invention relates to monoclonal anti-human-GDF-15 antibodies. The antibodies include chimeric antibodies and humanized antibodies. The invention also relates to monoclonal anti-human-GDF-15 antibodies including murine antibodies, chimeric antibodies and humanized antibodies for use in methods for the treatment of cancer cachexia and also for the treatment of cancer. The invention also provides pharmaceutical compositions, kits, methods and uses and cell lines capable of producing the monoclonal antibodies of the invention.
    Type: Application
    Filed: March 26, 2015
    Publication date: July 20, 2017
    Inventors: Jörg WISCHHUSEN, Markus JUNKER, Tina SCHÄFER, Dirk PÜHRINGER