Patents by Inventor Markus Kegel

Markus Kegel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing a substituted dimethyl-(3-arylbutyl)amine compound by homogeneous catalysis
    Patent number: 8791300
    Abstract: Compounds of the formula II can be hydrogenated to the corresponding butane derivatives in the presence of homogeneous cataslysts composed of metal salts or complexes containing metals selected from the group consisting of Rh, Ir, and Ru and preferably containing diphosphine ligands, with, in addition, excellent optical yields being achieved when one of R2 and R3 is not a hydrogen atom and the diphosphine ligand is chiral.
    Type: Grant
    Filed: May 1, 2008
    Date of Patent: July 29, 2014
    Assignee: Gruenenthal GmbH
    Inventors: Wolfgang Hell, Markus Kegel, Helmut Buschmann, Felix Spindler, Detlef Heller, Hans-Joachin Drexler
  • HCl Polymorphs of 3-((2-(Dimethylamino)methyl(cyclohex-1-yl))phenol
    Publication number: 20130245125
    Abstract: A crystalline salt of 3-[2-(dimethylamino)methyl(cyclohex-1-yl)] phenol and hydrogen chloride, preferably in a 1:1 composition, including various crystalline forms of this salt, processes for preparing the various crystalline forms of this salt, pharmaceutical compositions containing the various crystalline forms of this salt, and the use of this salt as a pharmacologically active agent in a pharmaceutical composition to treat or inhibit pain or other disorders or disease states.
    Type: Application
    Filed: May 1, 2013
    Publication date: September 19, 2013
    Applicant: GRUENENTHAL GmbH
    Inventors: Michael GRUSS, Andreas FISCHER, Markus KEGEL, Wolfgang HELL, Markus VON RAUMER, Joerg BERGHAUSEN, Susan Margaret DE PAUL
  • Drive device for refrigerator doors
    Patent number: 8347553
    Abstract: An arrangement comprises a housing, in particular of a cooling and/or freezing device, a door which is articulated to the housing so as to be pivotable about a pivot axis of a hinge, and at least one drive device for pivoting the door relative to the housing, with the drive device comprising a drive unit by means of which a moment is exertable on the door relative to the hinge axis via at least one force transmission means.
    Type: Grant
    Filed: July 24, 2009
    Date of Patent: January 8, 2013
    Assignees: SUSPA GmbH, Liebherr-Hausgeraete Ochsenhausen GmbH
    Inventors: Josef Hecht, Dietmar Blersch, Armin Pfister, Florian Stephan, Jens Scharg, Markus Kegel, Herbert Müller
  • HCI polymorphs of 3-((2-(dimethylamino)methyl(cyclohex-1-yl)) phenol
    Patent number: 8058476
    Abstract: A crystalline salt of 3-[2-(dimethylamino)methyl(cyclohex-1-yl)]phenol and hydrogen chloride, preferably in a 1:1 composition, including various crystalline forms of this salt, processes for preparing the various crystalline forms of this salt, pharmaceutical compositions containing the various crystalline forms of this salt, and the use of this salt as a pharmacologically active agent in a pharmaceutical composition to treat or inhibit pain or other disorders or disease states.
    Type: Grant
    Filed: January 18, 2008
    Date of Patent: November 15, 2011
    Assignee: Gruenenthal GmbH
    Inventors: Michael Gruss, Andreas Fischer, Markus Kegel, Wolfgang Hell, Markus Von Raumer, Joerg Berghausen, Susan Margaret Paul
  • HCI POLYMORPHS OF 3-((2-(DIMETHYLAMINO)METHYL (CYCLOHEX-1-YL))PHENOL
    Publication number: 20110251287
    Abstract: A crystalline salt of 3-[2-(dimethylamino)methyl(cyclohex-1-yl)]phenol and hydrogen chloride, preferably in a 1:1 composition, including various crystalline forms of this salt, processes for preparing the various crystalline forms of this salt, pharmaceutical compositions containing the various crystalline forms of this salt, and the use of this salt as a pharmacologically active agent in a pharmaceutical composition to treat or inhibit pain or other disorders or disease states.
    Type: Application
    Filed: June 21, 2011
    Publication date: October 13, 2011
    Applicant: Gruenenthal GmbH
    Inventors: Michael GRUSS, Andreas Fischer, Markus Kegel, Wolfgang Hell, Markus Von Raumer, Joerg Berghausen, Susan Margaret Paul
  • Process for producing 6-dimethylaminomethyl-phenyl-cyclohexane-1,3-diols
    Patent number: 7858826
    Abstract: A process for producing 6-dimethylaminomethyl-1-(3-hydroxy- or 3-C1-C4 alkoxyphenyl)-cyclohexane-1,3-diols from 6-dimethylaminomethyl-1-hydroxy-1-(3-hydroxy- or 3-C1-C4 alkoxyphenyl)-cyclohexane-3-ones by catalytic hydrogenation in the presence of heterogeneous or homogeneous catalysts, or by using metal hydrides.
    Type: Grant
    Filed: February 27, 2009
    Date of Patent: December 28, 2010
    Assignee: Gruenenthal GmbH
    Inventors: Wolfgang Hell, Oswald Zimmer, Markus Kegel, Olaf Schaefer, Felix Spindler, Anita Schnyder, Urs Siegrist, Detlef Heller, Hans-Joachim Drexler
  • HCl Polymorphs of 3-((2-(Dimethylamino)methyl-(cyclohex-1-yl))phenol
    Publication number: 20100076085
    Abstract: A crystalline salt of 3-[2-(dimethylamino)methyl(cyclohex-1-yl)]phenol and hydrogen chloride, preferably in a 1:1 composition, including various crystalline forms of this salt, processes for preparing the various crystalline forms of this salt, pharmaceutical compositions containing the various crystalline forms of this salt, and the use of this salt as a pharmacologically active agent in a pharmaceutical composition to treat or inhibit pain or other disorders or disease states.
    Type: Application
    Filed: November 30, 2009
    Publication date: March 25, 2010
    Applicant: Gruenenthal GmbH
    Inventors: Michael Gruss, Andreas Fischer, Markus Kegel, Wolfgang Hell, Markus Von Raumer, Joerg Berghausen, Susan Margaret Paul
  • DRIVE DEVICE FOR REFRIGERATOR DOORS
    Publication number: 20100018122
    Abstract: An arrangement comprises a housing, in particular of a cooling and/or freezing device, a door which is articulated to the housing so as to be pivotable about a pivot axis of a hinge, and at least one drive device for pivoting the door relative to the housing, with the drive device comprising a drive unit by means of which a moment is exertable on the door relative to the hinge axis via at least one force transmission means.
    Type: Application
    Filed: July 24, 2009
    Publication date: January 28, 2010
    Applicants: SUSPA Holding Gmbh, Liebherr-Hausgerate Ochsenhausen GmbH
    Inventors: Josef HECHT, Dietmar Blersch, Armin Pfister, Florian Stephan, Jens Scharf, Markus Kegel, Herbert Müller
  • Process for Producing 6-Dimethylaminomethyl-phenyl-cyclohexane-1,3-diols
    Publication number: 20090227813
    Abstract: A process for producing 6-dimethylaminomethyl-1-(3-hydroxy- or 3-C1-C4 alkoxyphenyl)-cyclohexane-1,3-diols from 6-dimethylaminomethyl-1-hydroxy-1-(3-hydroxy- or 3-C1-C4 alkoxyphenyl)-cyclohexane-3-ones by catalytic hydrogenation in the presence of heterogeneous or homogeneous catalysts, or by using metal hydrides.
    Type: Application
    Filed: February 27, 2009
    Publication date: September 10, 2009
    Applicant: Gruenenthal GmbH
    Inventors: Wolfgang Hell, Oswald Zimmer, Markus Kegel, Olaf Schaefer, Felix Spindler, Anita Schnyder, Urs Siegrist, Detlef Heller, Hans-Joachim Drexler
  • Process for Preparing a Substituted Dimethyl-(3-arylbutyl)amine Compound by Homogeneous Catalysis
    Publication number: 20090043132
    Abstract: Compounds of the formula II can be hydrogenated to the corresponding butane derivatives in the presence of homogeneous cataslysts composed of metal salts or complexes containing metals selected from the group consisting of Rh, Ir, and Ru and preferably containing diphosphine ligands, with, in addition, excellent optical yields being achieved when one of R2 and R3 is not a hydrogen atom and the diphosphine ligand is chiral.
    Type: Application
    Filed: May 1, 2008
    Publication date: February 12, 2009
    Applicant: Gruenenthal GmbH
    Inventors: Wolfgang Hell, Markus Kegel, Helmut Buschmann, Felix Spindler, Detlef Heller, Hans-Joachin Drexler
  • HCI POLYMORPHS OF 3-((2-(DIMETHYLAMINO)METHYL(CYCLOHEX-1-YL)) PHENOL
    Publication number: 20080255242
    Abstract: A crystalline salt of 3-[2-(dimethylamino)methyl(cyclohex-1-yl)] phenol and hydrogen chloride, preferably in a 1:1 composition, including various crystalline forms of this salt, processes for preparing the various crystalline forms of this salt, pharmaceutical compositions containing the various crystalline forms of this salt, and the use of this salt as a pharmacologically active agent in a pharmaceutical composition to treat or inhibit pain or other disorders or disease states.
    Type: Application
    Filed: January 18, 2008
    Publication date: October 16, 2008
    Applicant: Gruenenthal GmbH
    Inventors: Michael Gruss, Andreas Fischer, Markus Kegel, Wolfgang Hell, Markus Von Raumer, Joerg Berghausen, Susan Margaret Paul
  • Process for the preparation of substituted 3-aryl-butylamine compounds
    Patent number: 7417170
    Abstract: Methods for the dehydration of substituted 1-amino-3-aryl-butan-3-ol compounds for the preparation of substituted 3-aryl-butyl-amine compounds.
    Type: Grant
    Filed: December 6, 2005
    Date of Patent: August 26, 2008
    Assignee: Gruenenthal GmbH
    Inventors: Wolfgang Hell, Markus Kegel, Bernhard Akteries, Helmut Buschmann, Jorg Holenz, Harmut Loebermann, Detlef Heller, Hans-Joachim Drexler, Stefan Gladow
  • Process for chlorinating tertiary alcohols
    Patent number: 7235693
    Abstract: The present invention relates to a process for converting a tertiary OH group of an organic compound into a tertiary Cl group of the organic compound by using a solvent selected from the group comprising toluene, o-xylene, m-xylene, p-xylene and mixtures thereof, and thionyl chloride as the chlorinating agent.
    Type: Grant
    Filed: October 26, 2004
    Date of Patent: June 26, 2007
    Assignee: Gruenenthal GmbH
    Inventors: Helmut Buschmann, Wolfgang Hell, Markus Kegel
  • Process for chlorinating tertiary alcohols
    Publication number: 20070142681
    Abstract: The present invention relates to a process for converting a tertiary OH group of an organic compound into a tertiary C1 group of the organic compound by using a solvent selected from the group comprising toluene, o-xylene, m-xylene, p-xylene and mixtures thereof, and thionyl chloride as the chlorinating agent.
    Type: Application
    Filed: February 9, 2007
    Publication date: June 21, 2007
    Applicant: GRUENENTHAL GmbH
    Inventors: Helmut Buschmann, Wolfgang Hell, Markus Kegel
  • Process for the preparation of substitued 3-aryl-butylamine compounds
    Publication number: 20060194988
    Abstract: Methods for the dehydration of substituted 1-amino-3-aryl-butan-3-ol compounds for the preparation of substituted 3-aryl-butyl-amine compounds.
    Type: Application
    Filed: December 6, 2005
    Publication date: August 31, 2006
    Inventors: Wolfgang Hell, Markus Kegel, Berhard Akteries, Helmut Buschmann, Joerg Holenz, Harmut Loebermann, Detlef Heller, Hans-Joachim Drexler, Stefan Gladow
  • Process for chlorinating tertiary alcohols
    Publication number: 20050119349
    Abstract: The present invention relates to a process for converting a tertiary OH group of an organic compound into a tertiary Cl group of the organic compound by using a solvent selected from the group comprising toluene, o-xylene, m-xylene, p-xylene and mixtures thereof, and thionyl chloride as the chlorinating agent.
    Type: Application
    Filed: October 26, 2004
    Publication date: June 2, 2005
    Applicant: Gruenenthal GmbH
    Inventors: Helmut Buschmann, Wolfgang Hell, Markus Kegel