Patents by Inventor Markus Kircher

Markus Kircher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enzymatic asymmetric decarboxylation of disubstituted malonic acids
    Patent number: 7981645
    Abstract: A process for the stereoselective decarboxylation of malonic acid derivatives with mutated decarboxylases is disclosed.
    Type: Grant
    Filed: February 4, 2005
    Date of Patent: July 19, 2011
    Assignee: BioSpring GmbH
    Inventors: Hüseyin Aygün, Sylvia Wojczewski, Markus Kircher, Susann Rosmus
  • Enzymatic Asymmetric Decarboxylation of Disubstituted Malonic Acids
    Publication number: 20100144010
    Abstract: A process for the stereoselective decarboxylation of malonic acid derivatives with mutated decarboxylases is disclosed.
    Type: Application
    Filed: February 4, 2005
    Publication date: June 10, 2010
    Inventors: Hüseyin Aygün, Sylvia Wojczewski, Markus Kircher, Susann Rosmus
  • Method for the manufacture of DNA
    Publication number: 20030152984
    Abstract: The present invention relates to a method for manufacturing DNA comprising the steps of preparing n single stranded base-DNA-oligonucleotides which form immediately consecutive parts of the nucleotide sequence of the DNA being manufactured, in which the second to the n-th base-DNA-oligonucleotide is phosphorylated at the 5′ end and n is at least 2; preparing at least (n−1) single stranded joint-DNA-oligonucleotides capable of functioning as ligation templates for the base-DNA-oligonucleotides; contacting the base-DNA-oligonucleotides with the joint-DNA-oligonucleotides; subjecting the resultant product DNA-hybrid to a ligation reaction; and finally subjecting the resultant reaction product to an exonuclease reaction, in which the DNA strand of the reaction product formed by ligated base-DNA-oligonucleotides includes at least two cap-structures. Further the invention relates to DNA obtained by the method and a kit for carrying out the method.
    Type: Application
    Filed: January 13, 2003
    Publication date: August 14, 2003
    Inventors: Huseyin Aygun, Markus Kircher, Susann Rosmus, Sylvia Wojczewski