Patents by Inventor Markus Klein

Markus Klein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9656949
    Abstract: The present invention relates to compounds of the formula I and in particular medicaments comprising at least one compound of the formula I for use in the treatment and/or prophylaxis of physiological and/or pathophysiological states in the triggering of which ADAMTS5 is involved, in particular for use in the treatment and/or prophylaxis of osteoarthritis, hepatocirrhosis, traumatic cartilage injuries, pain, allodynia or hyperalgesia.
    Type: Grant
    Filed: January 16, 2014
    Date of Patent: May 23, 2017
    Assignee: MERCK PATENT GMBH
    Inventors: Markus Klein, Sven Lindemann
  • Patent number: 9647186
    Abstract: A method for producing an electronic component comprising barrier layers for the encapsulation of the component comprises, in particular, the following steps: providing a substrate with at least one functional layer, applying at least one first barrier layer on the functional layer via plasma enhanced atomic layer deposition (PEALD), and applying at least one second barrier layer on the functional layer by means of plasma-enhanced chemical vapor deposition (PECVD), where the at least one first barrier layer is applied at a temperature of less than 100° C.
    Type: Grant
    Filed: January 24, 2014
    Date of Patent: May 9, 2017
    Assignee: OSRAM OLED GmbH
    Inventors: Christian Schmid, Tilman Schlenker, Heribert Zull, Ralph Paetzold, Markus Klein, Karsten Heuser
  • Patent number: 9624264
    Abstract: The present invention relates to compounds of the formula (I) and in particular to medicaments comprising at least one compound of the formula (I) for use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions in the triggering of which cathepsin D is involved, in particular for use in the treatment and/or prophylaxis of arthrosis, traumatic cartilage injuries arthritis, pain, allodynia or hyperalgesia.
    Type: Grant
    Filed: June 26, 2013
    Date of Patent: April 18, 2017
    Assignee: Merck Patent GmbH
    Inventors: Christos Tsaklakidis, Markus Klein
  • Publication number: 20170081361
    Abstract: The present invention relates to compounds of the formula (I) and in particular to medicaments comprising at least one compound of the formula (I) for use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions in the triggering of which cathepsin D is involved, in particular for use in the treatment and/or prophylaxis of arthrosis, traumatic cartilage injuries arthritis, pain, allodynia or hyperalgesia.
    Type: Application
    Filed: November 30, 2016
    Publication date: March 23, 2017
    Applicant: Merck Patent GmbH
    Inventors: Christos TSAKLAKIDIS, Markus KLEIN
  • Publication number: 20160238234
    Abstract: A glazing comprising a luminous means with a substrate having a first main surface, to which a first electrode is applied, a second electrode, and an organic layer stack within an active region of the substrate between the first and the second electrode, wherein the organic layer stack comprises at least one organic layer which is suitable for generating light, wherein the luminous means is arranged between two glass plates of the glazing of a window. Also, storage furniture is disclosed comprising a storage element shaped in planar fashion and having at least one storage surface and at least one radiation-emitting component, and at least one holding apparatus for holding the storage element.
    Type: Application
    Filed: February 12, 2016
    Publication date: August 18, 2016
    Inventors: Karsten Diekmann, Karsten Heuser, Markus Klein, Dieter Lang, Georg Lechermann, Michael Reithmeier, Carsten Plumeyer, Makarand H. Chipalkatti, Udo Custodis, Diane Seymour, Dmytro Poplavskyy, Reinhard Weitzel
  • Publication number: 20160228493
    Abstract: The present invention relates to compounds of the formula (I) and in particular medicaments comprising at least one compound of the formula (I) for use in the treatment and/or prophylaxis of physiological and/or pathophysiological states in the triggering of which cathepsin D is involved, in particular for use in the treatment and/or prophylaxis of arthrosis, traumatic cartilage injuries, arthritis, pain, allodynia or hyperalgesia.
    Type: Application
    Filed: February 11, 2016
    Publication date: August 11, 2016
    Applicant: Merck Patent GmbH
    Inventors: Markus KLEIN, Christos TSAKLAKIDIS, Hans GUEHRING, Brigitta LEUTHNER
  • Publication number: 20160175381
    Abstract: The present invention relates to pharmaceutical preparations and medicaments for intraarticular administration, comprising pepstatin, and to the preparation and use thereof, in particular in the treatment and/or prophylaxis of arthrosis, traumatic cartilage injuries, arthritis, pain, allodynia or hyperalgesia, particularly preferably in arthrosis.
    Type: Application
    Filed: July 7, 2014
    Publication date: June 23, 2016
    Applicant: Merck Patent GmbH
    Inventors: Markus KLEIN, Ralf WODOPIA, Hans GUEHRING, Sven LINDEMANN
  • Publication number: 20160145297
    Abstract: The present invention relates to compounds of the formula I and in particular medicaments comprising at least one compound of the formula I for use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions in the triggering of which cathepsin D is involved, in particular for use in the treatment and/or prophylaxis of arthrosis, traumatic cartilage injuries, arthritis, pain, allodynia or hyperalgesia.
    Type: Application
    Filed: May 14, 2014
    Publication date: May 26, 2016
    Applicant: MERCK PATENT GMBH
    Inventor: Markus KLEIN
  • Patent number: 9345742
    Abstract: The present invention relates to compounds of the formula (I) and in particular medicaments comprising at least one compound of the formula (I) for use in the treatment and/or prophylaxis of physiological and/or pathophysiological states in the triggering of which cathepsin D is involved, in particular for use in the treatment and/or prophylaxis of arthrosis, traumatic cartilage injuries, arthritis, pain, allodynia or hyperalgesia.
    Type: Grant
    Filed: January 9, 2012
    Date of Patent: May 24, 2016
    Assignee: MERCK PATENT GMBH
    Inventors: Markus Klein, Christos Tsaklakidis, Hans Guehring, Brigitta Leuthner
  • Patent number: 9312308
    Abstract: An organic luminous means and an illumination device comprising such a luminous means are specified. An optical display apparatus, emergency lighting, motor vehicle interior lighting, an item of furniture, a construction material, a glazing and a display comprising such a luminous means and, respectively, comprising an illumination device having such a luminous means are furthermore specified.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: April 12, 2016
    Assignees: OSRAM OLED GmbH, OSRAM SYLVANIA INC.
    Inventors: Karsten Diekmann, Karsten Heuser, Markus Klein, Dieter Lang, Georg Lechermann, Michael Reithmeier, Carsten Plumeyer, Makarand H. Chipalkatti, Udo Custodis, Diane Seymour, Dmytro Poplavskyy, Reinhard Weitzel
  • Publication number: 20160013369
    Abstract: An optoelectronic component, comprising: a carrier (1) and a semiconductor layer sequence (20) configured for emission of electromagnetic primary radiation and arranged on the carrier (10). The semiconductor layer sequence (20) comprises a radiation main side (21) facing away from the carrier. A connecting layer is applied directly at least on the radiation main side (21) of the semiconductor layer sequence. A conversion element (40) is configured for emission of electromagnetic secondary radiation and is arranged directly on connecting layer (30), and being formed as a prefabricated body. Connecting layer (30) comprises at least one inorganic filler (31) embedded in matrix material and being formed with a layer thickness of less than or equal to 2 ?m. The prefabricated body is attached to the semiconductor layer sequence by the connecting layer which is configured in order to filter out a short-wave component of the electromagnetic primary radiation.
    Type: Application
    Filed: March 4, 2014
    Publication date: January 14, 2016
    Applicant: OSRAM OPTO SEMICONDUCTORS GMBH
    Inventors: Kathy SCHMIDTKE, Ion STOLL, Tony ALBRECHT, Markus KLEIN
  • Publication number: 20150368188
    Abstract: The present invention relates to compounds of the formula I and in particular medicaments comprising at least one compound of the formula I for use in the treatment and/or prophylaxis of physiological and/or pathophysiological states in the triggering of which ADAMTS5 is involved, in particular for use in the treatment and/or prophylaxis of osteoarthritis, hepatocirrhosis, traumatic cartilage injuries, pain, allodynia or hyperalgesia.
    Type: Application
    Filed: January 16, 2014
    Publication date: December 24, 2015
    Applicant: MERCK PATENT GMBH
    Inventors: Markus KLEIN, Sven LINDEMANN
  • Publication number: 20150361037
    Abstract: The present invention relates to compounds of the formula (I) and in particular to medicaments comprising at least one compound of the formula I for use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions in the triggering of which cathepsin D is involved, in particular for use in the treatment and/or prophylaxis of osteoarthritis, traumatic cartilage injuries, arthritis, pain, allodynia or hyperalgesia.
    Type: Application
    Filed: December 16, 2013
    Publication date: December 17, 2015
    Applicant: Merck Patent GmbH
    Inventors: Christos TSAKLAKIDIS, Markus KLEIN, Paul CZODROWSKI
  • Publication number: 20150361053
    Abstract: The present invention relates to compounds of the formula (I) and in particular to medicaments comprising at least one compound of the formula (I) for use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions in the triggering of which cathepsin D is involved, in particular for use in the treatment and/or prophylaxis of osteoarthritis, traumatic cartilage injuries, arthritis, pain, allodynia or hyperalgesia.
    Type: Application
    Filed: January 20, 2014
    Publication date: December 17, 2015
    Applicant: Merck Patent GmbH
    Inventors: Markus KLEIN, Christos TSAKLAKIDIS
  • Patent number: 9156354
    Abstract: A driver assistance system for a vehicle is provided. The driver assistance system includes a detecting device, which is designed to detect driving data that characterize the driving state of the vehicle, and a controller, which is designed to process the driving data detected by the detecting device and, if predetermined driving data are present, trigger a braking device to perform autonomous braking of the vehicle. The controller is also designed such that if driving data that indicate an imminent collision with an obstacle are detected, the function of the detecting device is monitored. If the detecting device no longer provides any driving data or plausible driving data to the controller, a continuation of the autonomous braking is triggered, at least until the vehicle has been decelerated to a specified speed.
    Type: Grant
    Filed: March 21, 2014
    Date of Patent: October 13, 2015
    Assignee: KNORR-BREMSE Systeme fuer Nutzfahrzeuge GmbH
    Inventors: Mark Rossi, Thomas Hackl, Jochen Banspach, Ulrich Guecker, Markus Klein
  • Publication number: 20150225451
    Abstract: The present invention relates to compounds of the formula (I) and in particular to medicaments comprising at least one compound of the formula (I) for use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions in the triggering of which cathepsin D is involved, in particular for use in the treatment and/or prophylaxis of arthrosis, traumatic cartilage injuries arthritis, pain, allodynia or hyperalgesia.
    Type: Application
    Filed: June 26, 2013
    Publication date: August 13, 2015
    Applicant: Merck Patent GmbH
    Inventors: Christos Tsaklakidis, Markus Klein
  • Publication number: 20150228696
    Abstract: An organic luminous means and an illumination device comprising such a luminous means are specified. An optical display apparatus, emergency lighting, motor vehicle interior lighting, an item of furniture, a construction material, a glazing and a display comprising such a luminous means and, respectively, comprising an illumination device having such a luminous means are furthermore specified.
    Type: Application
    Filed: January 16, 2015
    Publication date: August 13, 2015
    Inventors: Karsten DIEKMANN, Karsten Heuser, Markus Klein, Dieter Lang, Georg Lechermann, Michael Reithmeier, Carsten Plumeyer, Makarand H. Chipalkatti, Udo Custodis, Diane Seymour, Dmytro Poplavskyy, Reinhard Weitzel
  • Patent number: 9006255
    Abstract: Compounds of the formula I in which R, X, L2 and A1-A6 have the meanings indicated in Claim 1, are PI3K inhibitors and can be employed, inter alia, for the treatment of autoimmune diseases, inflammation, cardiovascular diseases, neurodegenerative diseases and tumors.
    Type: Grant
    Filed: September 22, 2011
    Date of Patent: April 14, 2015
    Assignee: Merck Patent GmbH
    Inventor: Markus Klein
  • Publication number: 20150072451
    Abstract: A method for producing an electronic component and an electronic component, having barrier layers for the encapsulation of the component. The method involves providing a substrate (1) with at least one functional layer (22), and an electronic component, applying at least one first barrier layer (3) on the functional layer (22) by way of plasmaless atomic layer deposition (PLALD), and applying at least one second barrier layer (4) on the functional layer (22) by way of plasma-enhanced chemical v0apor deposition (PECVD).
    Type: Application
    Filed: November 13, 2014
    Publication date: March 12, 2015
    Inventors: Christian Schmid, Tilman Schlenker, Heribert Zull, Ralph Paetzold, Markus Klein, Karsten Heuser
  • Patent number: 8946986
    Abstract: An organic luminous means and an illumination device comprising such a luminous means are specified. An optical display apparatus, emergency lighting, motor vehicle interior lighting, an item of furniture, a construction material, a glazing and a display comprising such a luminous means and, respectively, comprising an illumination device having such a luminous means are furthermore specified.
    Type: Grant
    Filed: November 5, 2012
    Date of Patent: February 3, 2015
    Assignee: OSRAM Opto Semiconductors GmbH
    Inventors: Karsten Diekmann, Karsten Heuser, Markus Klein, Dieter Lang, Georg Lechermann, Michael Reithmeier, Carsten Plumeyer, Makarand H. Chipalkatti, Udo Custodis, Diane Seymour, Dmytro Poplavskyy