Abstract: The invention relates to heterocyclic compounds, pharmaceutically acceptable salts thereof, and pharmaceutical preparations thereof. Also described herein are compositions and the use of such compounds in methods of treating diseases and conditions mediated by deficient CFTR activity, in particular cystic fibrosis.

Abstract: A swinging-sliding door for a vehicle, particularly for a public transport vehicle, with fastening components for fastening the swinging-sliding door on the vehicle and a door leaf that can be displaced between a closed position and an open position via intermediate positions, and with a door leaf displacement device for displacing the door leaf, wherein the door leaf displacement device has a controllable actuator, as well as a guide element that can be adjusted by the controllable actuator, and wherein the open position and/or the intermediate positions of the door leaf can be changed by adjusting the adjustable guide element.

Abstract: The disclosure relates to a vehicle lock having a locking mechanism, a lock mechanism and an electrical setting arrangement, wherein the setting arrangement has a rotor arrangement, and a stator, wherein the stator forms at least two magnetic, unlike stator poles of the stator magnet arrangement, wherein at least one of the magnet arrangements is associated with a coil arrangement, wherein by supplying current to the coil arrangement and a resulting magnetic interaction between rotor and stator, a drive torque to the rotor and thus an adjustment of the rotor can be generated in a predetermined number of actuator positions. Proposed is that the rotor magnet arrangement and the stator magnet arrangement are stationarily fixed to a support section of the motor vehicle lock, and the rotor is pivotable about a rotor axis relative to the support section and relative to the rotor magnet arrangement.

Abstract: Various embodiments provide a vehicle lock with a supporting structure for holding at least one locking element and a lock mechanism, wherein the lock mechanism can be put into different function states and has a function element that can be moved into different function positions, wherein a drive assembly having a drive train to the function element is provided, wherein an actuating element is provided, by the actuating motion of which said locking element can be actuated, wherein the function element in one function position guides the actuating motion of the actuating element either into a free-movement path, in which the actuating element moves freely, or into an actuation path, in which the actuating element actuates the locking element, and for this purpose applies a guiding force to the actuating element, the force flow of which guiding force runs outside of the drive train of the drive assembly.

Abstract: A motor vehicle lock arrangement for a motor vehicle door which is adjustably coupled to a motor vehicle body work, wherein the motor vehicle lock arrangement has a motor vehicle lock wherein the motor vehicle lock arrangement has a push-open arrangement for applying a drive force to the motor vehicle door in its opening direction, so that the motor vehicle door can be adjusted, in a motor-operated push-open process, from a closed door position into a push-open door position which is located further in the opening direction of said motor vehicle door, and as a result an engagement gap can be produced between the motor vehicle door and the motor vehicle body work. It is proposed that the motor vehicle lock arrangement has a light arrangement and a light controller for actuating the light arrangement.

Abstract: A functional component of a motor vehicle lock arrangement, the functional component has a drive arrangement with a motor and an adjustment element coupled to the drive arrangement. The adjustment element can be deflected out of a predetermined engaged position in a deflecting movement, and the deflected adjustment element can be reset into the engaged position in a resetting movement. The deflecting movement can be produced by means of the drive arrangement and the drive motor operates in the motor mode, and the resetting movement is spring-driven and the drive motor operates in the generator mode. The functional component may include a monitoring unit which determines the position of the adjustment element reached in the resetting movement from the motor voltage of the drive motor in accordance with a monitoring rule.

Abstract: A motor vehicle lock arrangement for a motor vehicle door which is adjustably coupled to a motor vehicle body work, wherein the motor vehicle lock arrangement has a motor vehicle lock wherein the motor vehicle lock arrangement has a push-open arrangement for applying a drive force to the motor vehicle door in its opening direction, so that the motor vehicle door can be adjusted, in a motor-operated push-open process, from a closed door position into a push-open door position which is located further in the opening direction of said motor vehicle door, and as a result an engagement gap can be produced between the motor vehicle door and the motor vehicle body work. It is proposed that the motor vehicle lock arrangement has a light arrangement and a light controller for actuating the light arrangement.

Abstract: The disclosure relates to a vehicle lock having a locking mechanism, a lock mechanism and an electrical setting arrangement, wherein the setting arrangement has a rotor arrangement, wherein the stator forms at least two magnetic, unlike stator poles of the stator magnet arrangement, wherein at least one of the magnet arrangements is associated with a coil arrangement, wherein by supplying current to the coil arrangement and a resulting magnetic interaction between rotor and stator, a drive torque to the rotor and thus an adjustment of the rotor can be generated in a predetermined number of actuator positions. Proposed is that the rotor magnet arrangement and the stator magnet arrangement are stationarily fixed to a support section of the motor vehicle lock, and the rotor is pivotable about a rotor axis relative to the support section and relative to the rotor magnet arrangement.

Abstract: Various embodiments provide a vehicle lock with a supporting structure for holding at least one locking element and a lock mechanism, wherein the lock mechanism can be put into different function states and has a function element that can be moved into different function positions, wherein a drive assembly having a drive train to the function element is provided, wherein an actuating element is provided, by the actuating motion of which said locking element can be actuated, wherein the function element in one function position guides the actuating motion of the actuating element either into a free-movement path, in which the actuating element moves freely, or into an actuation path, in which the actuating element actuates the locking element, and for this purpose applies a guiding force to the actuating element, the force flow of which guiding force runs outside of the drive train of the drive assembly.

Abstract: A motor vehicle lock having a positioning element, especially a control shaft, and a drive unit for moving the positioning element, wherein the drive unit has a rotor and a stator, the stator having a coil arrangement and at least two magnetically conducting poles associated with the coil arrangement for conducting the magnetic field created by the coil arrangement. It is proposed that the poles each time form, with the rotor, an axial air gap relative to the geometrical rotor axis, possibly in dependence on the rotor position, and a first segment of the coil arrangement with at least two coils and a second segment of the coil arrangement with at least two coils are arranged along the geometrical rotor axis on opposite sides of the rotor.

Abstract: A sliding door for a motor vehicle which is movable in a sliding motion into an opened and a closed position is provided with a main lock arrangement by which the sliding door can be fixed in the closed position, and an auxiliary lock arrangement which supplements the holding force of the main lock arrangement when the sliding door is in the closed position. In an improvement over conventional sliding door arrangements of this type, the auxiliary lock arrangement is used not only for supplementing the main lock arrangement when fixing the sliding door in the closed position, but also for fixing the door in the opened position.

Abstract: The present invention relates to a motor vehicle lock having a lock catch and a locking pawl. The lock catch may be brought into an opening position, a main locking position and a preliminary locking position. The locking pawl can be brought into a lowered and raised position. The locking pawl may be arranged to hold and release the lock catch in a direction of its opening position. A memory element is assigned to the locking pawl and arranged to keep the locking pawl in the raised position. The memory element may operate with a control apparatus. The locking pawl may be releasable by motor from the raised position and may further be moveable in a direction of its lowered position unhindered by the memory element. The release by motor of the locking pawl is controllable at a predetermined triggering time by the control apparatus.

Abstract: Sliding door arrangement for a motor vehicle having a lock arrangement, for fixing a sliding door in opened and closed positions, with a catch lever arrangement with a pivoting catch lever that is movable into engaged and raised states and is pretensioned toward the engaged state. The catch lever arrangement has first and second engagement elements with which the catch lever engageable, the catch lever, when the sliding door is in the opened position, engaging the first engagement element and the catch lever fixing the sliding door in the opened position. The catch lever is engageable with the second engagement element when the sliding door is in the closed position and the catch lever fixes the sliding door in the closed position. The arrangement is such that the pretensioning of the catch lever toward the engaged state rises by the movement of the sliding door into the closed position.

Abstract: A motor vehicle component with a drive having a motor, a gearing and a component which is movable by the drive, the motor being coupled to a driving side of the gearing and a driven side of the gearing being coupled to the movable component, a kinematic chain of the gearing between the driving side and the driven side having at least two transmission elements. The drive is operable in blocking operation by a displaceable blocking element that is movable into blocking engagement with the drive. The displaceable blocking element is in addition to the drive and the adjustable component, and is engaged in a controlling manner with the first transmission element of the kinematic chain so that, depending on the position of a first transmission element, it can be moved into blocking engagement with a second transmission element of the kinematic chain.

Abstract: Sliding door arrangement for a motor vehicle having a lock arrangement, for fixing a sliding door in opened and closed positions, with a catch lever arrangement with a pivoting catch lever that is movable into engaged and raised states and is pretensioned toward the engaged state. The catch lever arrangement has first and second engagement elements with which the catch lever engageable, the catch lever, when the sliding door is in the opened position, engaging the first engagement element and the catch lever fixing the sliding door in the opened position. The catch lever is engageable with the second engagement element when the sliding door is in the closed position and the catch lever fixes the sliding door in the closed position. The arrangement is such that the pretensioning of the catch lever toward the engaged state rises by the movement of the sliding door into the closed position.

Abstract: A sliding door for a motor vehicle which is movable in a sliding motion into an opened and a closed position is provided with a main lock arrangement by which the sliding door can be fixed in the closed position, and an auxiliary lock arrangement which supplements the holding force of the main lock arrangement when the sliding door is in the closed position. In an improvement over conventional sliding door arrangements of this type, the auxiliary lock arrangement is used not only for supplementing the main lock arrangement when fixing the sliding door in the closed position, but also for fixing the door in the opened position.

Abstract: The present invention relates to a motor vehicle lock having a lock catch and a locking pawl. The lock catch may be brought into an opening position, a main locking position and a preliminary locking position. The locking pawl can be brought into a lowered and raised position. The locking pawl may be arranged to hold and release the lock catch in a direction of its opening position. A memory element is assigned to the locking pawl and arranged to keep the locking pawl in the raised position. The memory element may operate with a control apparatus. The locking pawl may be releasable by motor from the raised position and may further be moveable in a direction of its lowered position unhindered by the memory element. The release by motor of the locking pawl is controllable at a predetermined triggering time by the control apparatus.

Abstract: A sliding door for a motor vehicle, the sliding door being movable by a sliding motion into an opened and into a closed position, and having a fixing arrangement (2). The fixing arrangement (2) has an engagement module (3) and an engagement element (4), the engagement module (3) engaging the engagement element (4) when the sliding door is moved into the opened position and in this way fixing the sliding door in the opened position. It is proposed that the engagement module (3), when the sliding door has been fixed in the opened position, can be actuated by a drive in a motorized manner so that, in this way, the engagement element (4) is released and the sliding door can then be moved in the closing direction.

Abstract: A motor vehicle lock with a latch and a ratchet, the latch being pivotable around a pivot axis, and being movable into an open position and into at least a fully latched position and the ratchet being movable into at least one holding position and into a release position, the ratchet holding the latch in the fully latched position in the holding position. Additional kinematics are coupled in a pivoting and undetachable manner to the latch so that the resetting motion of the latch out of the fully latched position in the direction of the open position causes movement of the additional kinematics and the additional kinematics are coupled to an elastic resistance element at least when the latch is in the fully latched position so that the action of the force of the resistance element on the additional kinematics causes inhibition of the first segment of the resetting motion.

Abstract: A motor vehicle component with a drive having a motor, a gearing and a component which is movable by the drive, the motor being coupled to a driving side of the gearing and a driven side of the gearing being coupled to the movable component, a kinematic chain of the gearing between the driving side and the driven side having at least two transmission elements. The drive is operable in blocking operation by a displaceable blocking element that is movable into blocking engagement with the drive. The displaceable blocking element is in addition to the drive and the adjustable component, and is engaged in a controlling manner with the first transmission element of the kinematic chain so that, depending on the position of a first transmission element, it can be moved into blocking engagement with a second transmission element of the kinematic chain.