Patents by Inventor Markus Loffler

Markus Loffler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180291083
    Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
    Type: Application
    Filed: April 10, 2018
    Publication date: October 11, 2018
    Inventors: Juliane Sarah WALZ, Daniel KOWALEWSKI, Markus LÖFFLER, Moreno DI MARCO, Nico TRAUTWEIN, Annika NELDE, Stefan STEVANOVIC, Hans-Georg RAMMENSEE, Sebastian HAEN
  • Publication number: 20100277451
    Abstract: A display is disclosed, such as for a vehicle. A brightness sensor receives light from a flexible fiber-optic cable. An adapter element is provided proximate, such as between, the light output point of the optical fiber and the brightness sensor. The adapter element may be an angled piece, and may be extruded onto the optical cable.
    Type: Application
    Filed: June 11, 2008
    Publication date: November 4, 2010
    Applicant: Johnson Control Technology Company
    Inventors: Thomas Arheit, Markus Loffler, Gerhard Kammerer, Detlef Kuehn
  • Patent number: 7823559
    Abstract: In an internal combustion engine including a camshaft for operating inlet and outlet valves of the engine with lift curves EV, AV of the inlet and the outlet valves determined by the shape of cams of the camshaft, an additional auxiliary cam which acts on the outlet valve is arranged on the camshaft, as a result of which a phase-offset auxiliary lift curve AVZ is impressed onto the outlet valve.
    Type: Grant
    Filed: February 9, 2009
    Date of Patent: November 2, 2010
    Assignee: Daimler AG
    Inventors: Daniel Böhme, Markus Löffler, Siegfried Sumser
  • Publication number: 20090173313
    Abstract: In an internal combustion engine including a camshaft for operating inlet and outlet valves of the engine with lift curves EV, AV of the inlet and the outlet valves determined by the shape of cams of the camshaft, an additional auxiliary cam which acts on the outlet valve is arranged on the camshaft, as a result of which a phase-offset auxiliary lift curve AVZ is impressed onto the outlet valve.
    Type: Application
    Filed: February 9, 2009
    Publication date: July 9, 2009
    Inventors: Daniel Bohme, Markus Loffler, Siegfried Sumser
  • Publication number: 20060210739
    Abstract: The invention relates to a container having a wall structure comprising a polymer material including an acid diffusion barrier. The invention also relates to a use of a cycloolefin polymer, COP, and/or a cycloolefin copolymer, COC, as an acid diffusion barrier polymer in a container for an acid. The invention further relates to a use of such a container and to a system for providing a medical solution comprising at least one container according to the invention. Finally the invention relates to a method for treatment by means of a container according to the invention.
    Type: Application
    Filed: November 7, 2003
    Publication date: September 21, 2006
    Inventors: Markus Loffler, Reinhold Deppisch, Ernst Luppold, Patrik Dalholm
  • Patent number: 5331879
    Abstract: An electrothermal firing device (1) including a tube containing a charge chamber (4') in which a first electrode (9) is disposed at the end of the charge chamber (4') adjacent the breechblock (2) and a second electrode (10) is disposed at the end of the charge chamber adjacent the projectile (6). To permit the first electrode (9) adjacent the breechblock to be arranged in the charge chamber without expensive supports, in contrast to such prior art devices, this first electrode (9) is configured as the grounded electrode and the second electrode (10) is configured as the high voltage electrode. Preferably, the two electrodes (9, 10) are arranged in an exchangeable cartouche (18) so that conventional charge chambers employing corresponding loading devices can be retrofitted in a simple manner for use with electrothermal firing devices (1).
    Type: Grant
    Filed: October 1, 1992
    Date of Patent: July 26, 1994
    Assignee: TZN Forschungs-und Entwicklungszentrum Unterluss GmbH
    Inventor: Markus Loffler
  • Patent number: 5294850
    Abstract: An electromagnetic accelerator arrangement includes a stationary arrangement including at least one stationary primary coil, and a movable arrangement including at least one moveable secondary coil. The planes of the stationary and the moveable coils are parallel to a direction of movement of the moveable arrangement. The coils of the stationary and the movable arrangements have approximately the same coil width in the direction of movement of the moveable arrangement and transversely thereto, as well as the same coil separation in the direction of movement of the moveable arrangement. The at least one stationary primary coil includes at least two layers between which the at least one secondary coil of the movable component is movably disposed, the distance between the layers being kept small transversely to the direction of movement of the moveable arrangement.
    Type: Grant
    Filed: September 17, 1992
    Date of Patent: March 15, 1994
    Assignee: Rheinmetall GmbH
    Inventors: Herbert Weh, Hardo May, Markus Loffler
  • Patent number: 5272965
    Abstract: A rail gun for accelerating a projectile therein includes a hollow insulating body forming a gun tube; and two rail assemblies supported in the gun tube and together defining an acceleration channel to accommodate a projectile for being propelled therein by a plasma armature generated by a high intensity current flowing through the rail assemblies and an electric arc connecting the rail assemblies. At least one of the rail assemblies includes a layer of an electrically conducting metal wool mass extending along and bounding the acceleration channel and an insulating substance held in the metal wool mass.
    Type: Grant
    Filed: October 16, 1992
    Date of Patent: December 28, 1993
    Assignee: TZN Forschungs- und Entwicklungszentrum Unterluss GmbH
    Inventor: Markus Loffler
  • Patent number: 5115743
    Abstract: A propellant casing assembly for an electrothermic projectile firing device has a casing and an electrically energizable coil disposed in the casing. The coil vaporizes at a predetermined current intensity and generates at least one part of propellant gases for accelerating a projectile.
    Type: Grant
    Filed: June 12, 1990
    Date of Patent: May 26, 1992
    Assignee: TZN Forschungs- und Entwicklungszentrum Unterluss GmbH
    Inventor: Markus Loffler
  • Patent number: 5094141
    Abstract: An arrangement for the accelerating of a projectile through the intermediary of a plasma, wherein the plasma is generated by means of an electrical discharging circuit within a metallic tube which has the bottom thereof closed. The one pole of the discharging circuit contacts a first electrode which is formed on the tube rearwardly of the projectile, and in the other pole of the discharging circuit is connected with the casing or jacket of the tube. The projectile, which constitutes the second electrode, forms a current collector which contacts in the casing or jacket of the tube and slides therein during the acceleration of the projectile. The current collector hereby acts in the manner of a sliding contact which, during the acceleration of the projectile, remains in electrical contact with the tube.
    Type: Grant
    Filed: August 22, 1991
    Date of Patent: March 10, 1992
    Assignees: Diehl GmbH & Co., Rheinmetall GmbH
    Inventors: Dieter Zwingel, Klaus Zocha, Markus Loffler
  • Patent number: 5042359
    Abstract: A device for accelerating projectiles from a muzzle of a launching tube, with an electrically heated plasma, the plasma being produced by two electrodes between which is formed an electric arc that creates and heats the plasma. To assure in a simple manner that the pressure at the projectile base is almost constant during launching of the projectile, one of the two electrodes is provided at a breechblock of the tube and the other is formed by the base of the projectile.
    Type: Grant
    Filed: April 12, 1989
    Date of Patent: August 27, 1991
    Assignees: Rheinmetall GmbH, TZN Forschungs- und Entwicklungszentrum GmbH
    Inventors: Wolfram Witt, Markus Loffler, Ulrich Braunsberger, Jurgen Salge
  • Patent number: 4996455
    Abstract: An inductive energy converter includes a coil assembly having coil windings, with at least some of the coil windings respectively having spaced contact regions. A contact bar within the coil assembly is insulated from the coil windings, and a conductive body is in electrical contact with the contact bar and is movably supported by the coil assembly, wherein movement of the conductive body brings it into electrical contact with consecutive ones of the spaced contact regions, to complete an electrical circuit between one of the windings and the contact bar.
    Type: Grant
    Filed: February 16, 1990
    Date of Patent: February 26, 1991
    Assignees: TZN Forschungs-und Entwicklungszentrum Unterluss GmbH, Rheinmetall GmbH
    Inventors: Markus Loffler, Ulrich Braunsberger
  • Patent number: 4967637
    Abstract: A device for accelerating projectiles from a launching tube by means of an electrically heated plasma and two electrodes between which burns an electric arc so as to heat the plasma. To cause the pressure for accelerating the projectile in the launching tube to be as high as possible, the two electrodes and thus the electric arc which heats the plasma are disposed within a rear portion of the projectile.
    Type: Grant
    Filed: April 12, 1989
    Date of Patent: November 6, 1990
    Assignees: Rheinmetall GmbH, TZN Forschumgs-und Entwicklungszentrum Unterluss GmbH
    Inventors: Markus Loffler, Wolfram Witt
  • Patent number: 4930395
    Abstract: A projectile intended to be fired from an electric rail gun having spaced current-carrying rails between which the projectile is accelerated when fired, includes an armature mounted on the projectile and arranged to make contact simultaneously with the rails to electrically connect the rails to one another. The armature is of annular configuration and rotates as the projectile is propelled through the electric rail gun.
    Type: Grant
    Filed: May 15, 1989
    Date of Patent: June 5, 1990
    Assignee: TZN Forschungs- und Entwicklungszentrum Unterluss GmbH
    Inventor: Markus Loffler