Patents by Inventor Markus M. Heiss

Markus M. Heiss has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230310597
    Abstract: The present invention relates to methods for reducing or eliminating the non-specific release of a cytokine associated with a disease comprising administering at least one glucocorticoid and an immunostimulating antibody. Additionally, the present invention relates to a pharmaceutical composition that contains at least one immunostimulating antibody and at least one glucocorticoid.
    Type: Application
    Filed: January 30, 2023
    Publication date: October 5, 2023
    Inventors: Markus M. HEISS, Horst LINDHOFER
  • Patent number: 11406486
    Abstract: A suction stent for introduction into a hollow organ of the human or animal body, preferably into the gastrointestinal tract, in particular the intestine, includes a tubular hollow body which is open in the longitudinal direction and made of biocompatible material. The tubular hollow body has a fixed diameter at least in its central portion; and a porous shapeable material, preferably a sponge material, which is biocompatible and shapeable in the radial direction, the porous shapeable material radially sheathing the tubular hollow body at least in a section of the tubular hollow body. Further, a method is provided for sealing a leakage, especially an anastomosis, of the hollow organ.
    Type: Grant
    Filed: August 19, 2020
    Date of Patent: August 9, 2022
    Assignee: Vac Stent Medtec AG
    Inventor: Markus M. Heiss
  • Publication number: 20210015917
    Abstract: The present invention relates to methods for reducing or eliminating the non-specific release of a cytokine associated with a disease comprising administering at least one glucocorticoid and an immunostimulating antibody. Additionally, the present invention relates to a pharmaceutical composition that contains at least one immunostimulating antibody and at least one glucocorticoid.
    Type: Application
    Filed: February 6, 2020
    Publication date: January 21, 2021
    Inventors: Markus M. HEISS, Horst LINDHOFER
  • Publication number: 20200375718
    Abstract: A suction stent for introduction into a hollow organ of the human or animal body, preferably into the gastrointestinal tract, in particular the intestine, includes a tubular hollow body which is open in the longitudinal direction and made of biocompatible material. The tubular hollow body has a fixed diameter at least in its central portion; and a porous shapeable material, preferably a sponge material, which is biocompatible and shapeable in the radial direction, the porous shapeable material radially sheathing the tubular hollow body at least in a section of the tubular hollow body. Further, a method is provided for sealing a leakage, especially an anastomosis, of the hollow organ.
    Type: Application
    Filed: August 19, 2020
    Publication date: December 3, 2020
    Inventor: Markus M. Heiss
  • Patent number: 10779928
    Abstract: The invention relates to a suction stent for introduction into a hollow organ of the human or animal body, preferably into the gastrointestinal tract, in particular the intestine, comprising a tubular hollow body which is open in the longitudinal direction and made of biocompatible material, the tubular hollow body having a fixed diameter at least in its central portion; and a porous shapeable material, preferably a sponge material, which is biocompatible and shapeable in the radial direction, the porous shapeable material radially sheathing the tubular hollow body at least in a section of the tubular hollow body. Further, the invention relates to a method for sealing a leakage, especially an anastomosis, of the hollow organ.
    Type: Grant
    Filed: July 13, 2018
    Date of Patent: September 22, 2020
    Assignee: Vac Stent Medtec AG
    Inventor: Markus M. Heiss
  • Patent number: 10576149
    Abstract: The present invention relates to methods for reducing or eliminating the non-specific release of a cytokine associated with a disease comprising administering at least one glucocorticoid and an immunostimulating antibody. Additionally, the present invention relates to a pharmaceutical composition that contains at least one immunostimulating antibody and at least one glucocorticoid.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: March 3, 2020
    Assignee: Lindis Biotech GmbH
    Inventors: Markus M. Heiss, Horst Lindhofer
  • Publication number: 20190008630
    Abstract: The invention relates to a suction stent for introduction into a hollow organ of the human or animal body, preferably into the gastrointestinal tract, in particular the intestine, comprising a tubular hollow body which is open in the longitudinal direction and made of biocompatible material, the tubular hollow body having a fixed diameter at least in its central portion; and a porous shapeable material, preferably a sponge material, which is biocompatible and shapeable in the radial direction, the porous shapeable material radially sheathing the tubular hollow body at least in a section of the tubular hollow body. Further, the invention relates to a method for sealing a leakage, especially an anastomosis, of the hollow organ.
    Type: Application
    Filed: July 13, 2018
    Publication date: January 10, 2019
    Inventor: Markus M. Heiss
  • Patent number: 10071158
    Abstract: The present invention relates to methods for reducing or eliminating the non-specific release of a cytokine associated with a disease comprising administering at least one glucocorticoid and an immunostimulating antibody. Additionally, the present invention relates to a pharmaceutical composition that contains at least one immunostimulating antibody and at least one glucocorticoid.
    Type: Grant
    Filed: April 7, 2014
    Date of Patent: September 11, 2018
    Assignee: LINDIS BIOTECH GMBH
    Inventors: Markus M. Heiss, Horst Lindhofer
  • Patent number: 10058413
    Abstract: A suction stent for introduction into a hollow organ of the human or animal body, preferably into the gastrointestinal tract, in particular the intestine, includes a tubular hollow body which is open in the longitudinal direction and made of biocompatible material. The tubular hollow body has a fixed diameter at least in its central portion. A porous shapeable material, preferably a sponge material, which is biocompatible and shapeable in the radial direction, radially sheaths the tubular hollow body at least in a section of the tubular hollow body. A method for sealing a leakage, especially an anastomosis, of the hollow organ utilizes the stent.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: August 28, 2018
    Assignee: Vac Stent Medtec AG
    Inventor: Markus M. Heiss
  • Publication number: 20180236067
    Abstract: The present invention relates to methods for reducing or eliminating the non-specific release of a cytokine associated with a disease comprising administering at least one glucocorticoid and an immunostimulating antibody. Additionally, the present invention relates to a pharmaceutical composition that contains at least one immunostimulating antibody and at least one glucocorticoid.
    Type: Application
    Filed: March 23, 2018
    Publication date: August 23, 2018
    Inventors: Markus M. Heiss, Horst Lindhofer
  • Publication number: 20160367352
    Abstract: A suction stent for introduction into a hollow organ of the human or animal body, preferably into the gastrointestinal tract, in particular the intestine, includes a tubular hollow body which is open in the longitudinal direction and made of biocompatible material. The tubular hollow body has a fixed diameter at least in its central portion. A porous shapeable material, preferably a sponge material, which is biocompatible and shapeable in the radial direction, radially sheaths the tubular hollow body at least in a section of the tubular hollow body. A method for sealing a leakage, especially an anastomosis, of the hollow organ utilizes the stent.
    Type: Application
    Filed: December 13, 2013
    Publication date: December 22, 2016
    Inventor: Markus M. Heiss
  • Publication number: 20150086550
    Abstract: The present invention relates to methods for reducing or eliminating the non-specific release of a cytokine associated with a disease comprising administering at least one glucocorticoid and an immunostimulating antibody. Additionally, the present invention relates to a pharmaceutical composition that contains at least one immunostimulating antibody and at least one glucocorticoid.
    Type: Application
    Filed: April 7, 2014
    Publication date: March 26, 2015
    Inventors: Markus M. Heiss, Horst Lindhofer
  • Patent number: 8709421
    Abstract: The present invention relates to methods for reducing or eliminating the non-specific release of a cytokine associated with a disease comprising administering at least one glucocorticoid and an immunostimulating antibody. Additionally, the present invention relates to a pharmaceutical composition that contains at least one immunostimulating antibody and at least one glucocorticoid.
    Type: Grant
    Filed: October 26, 2007
    Date of Patent: April 29, 2014
    Assignee: Trion Pharma GmbH
    Inventors: Markus M. Heiss, Horst Lindhofer
  • Patent number: 8663638
    Abstract: The invention describes the use of trifunctional bispecific and trispecific antibodies for destroying tumor cells which e.g. are disseminated intraperitoneally due to a surgical intervention, wherein the antibody is administered intraoperatively, preferably directly locally into the abdominal cavity.
    Type: Grant
    Filed: September 4, 2008
    Date of Patent: March 4, 2014
    Assignee: Trion Pharma GmbH
    Inventors: Horst Lindhofer, Markus M. Heiss
  • Publication number: 20100322933
    Abstract: The invention describes the use of trifunctional bispecific and trispecific antibodies for destroying tumor cells which e.g. are disseminated intraperitoneally due to a surgical intervention, wherein the antibody is administered intraoperatively, preferably directly locally into the abdominal cavity.
    Type: Application
    Filed: September 4, 2008
    Publication date: December 23, 2010
    Applicant: TRION Pharma GmbH
    Inventors: Horst Lindhofer, Markus M. Heiss
  • Publication number: 20090191201
    Abstract: The present invention relates to methods for reducing or eliminating the non-specific release of a cytokine associated with a disease comprising administering at least one glucocorticoid and an immunostimulating antibody. Additionally, the present invention relates to a pharmaceutical composition that contains at least one immunostimulating antibody and at least one glucocorticoid.
    Type: Application
    Filed: October 26, 2007
    Publication date: July 30, 2009
    Inventors: Markus M. Heiss, Horst Lindhofer