Patents by Inventor Markus Magerlein

Markus Magerlein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7846477
    Abstract: The invention concerns a method for producing solid galenic formulations which consists in: forming a processable paste comprising a) 50 to 99.4 wt. % of at least one non-thermoplastic carrier, b) 0.5 to 30 wt. % of at least an adjuvant selected among thermoplastic polymers, lipids, sugar alcohols and solubilizing agents, c) 0.1 to 49.5 wt. % of at least one active principle, at a temperature not less than the softening temperature of the adjuvant but rising to at least 70° C.; then in cooling the resulting paste. Said solid galenic formulations quickly disintegrate in an aqueous medium.
    Type: Grant
    Filed: October 9, 2003
    Date of Patent: December 7, 2010
    Assignee: Abbott GmbH & Co. KG
    Inventors: Jörg Rosenberg, Gunther Berndl, Markus Magerlein
  • Publication number: 20090012184
    Abstract: A method is described for the production of dosage forms, which comprise a solid dispersion of a microcrystalline active substance, in which a thermoplastic polymer with a glass transition temperature Tg of at least 40° C. is melted and an active substance is dissolved homogeneously in the melt; crystallization of the active substance is initiated in the mass obtained; and the mass is cooled. Crystallization of the active substance can be initiated by adding a nonsolvent, seed crystals of the active substance or a derivatization reagent. In addition, crystallization can be initiated by holding the mass for a sufficient length of time at a temperature that is below the temperature at which the active substance is completely soluble in the mass.
    Type: Application
    Filed: February 9, 2006
    Publication date: January 8, 2009
    Applicant: ABBOTT GMBH & CO. KG
    Inventors: Jorg Rosenberg, Markus Magerlein, Bernd Liepold, Jorg Breitenbach
  • Publication number: 20060257470
    Abstract: The invention concerns a method for producing solid galenic formulations which consists in: forming a processable paste comprising a) 50 to 99.4 wt. % of at least one non-thermoplastic carrier, b) 0.5 to 30 wt. % of at least an adjuvant selected among thermoplastic polymers, lipids, sugar alcohols and solubilizing agents, c) 0.1 to 49.5 wt. % of at least one active principle, at a temperature not less than the softening temperature of the adjuvant but rising to at least 70° C.; then in cooling the resulting paste. Said solid galenic formulations quickly disintegrate in an aqueous medium.
    Type: Application
    Filed: October 9, 2003
    Publication date: November 16, 2006
    Applicant: Abbott GmbH & Co. KG
    Inventors: Joerg Rosenberg, Gunther Berndl, Markus Magerlein
  • Patent number: 6030790
    Abstract: The present invention is directed to peptides from the sequence of hPTH(1-37), which contain .alpha.-helical amino acid sequence regions and/or non-structured amino acid sequence regions, said peptides being capable of inducing antibodies when injected into animals. Furthermore, the invention is directed to a diagnostic agent and antibodies obtainable by immunizing animals using the peptides according to the invention.
    Type: Grant
    Filed: March 27, 1997
    Date of Patent: February 29, 2000
    Assignee: Haemopep Pharma GmbH
    Inventors: Knut Adermann, Dieter Hock, Markus Magerlein