Patents by Inventor Markus Peter Kummer

Markus Peter Kummer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of the nitration of amyloid ? peptides and their uses in the diagnosis and treatment of Alzheimer's disease
    Patent number: 9011862
    Abstract: The present invention relates to a method for identifying an inhibitor of the aggregation of amyloid-? peptide (A?), comprising the steps of a) contacting at least one A? -peptide and/or the nitrated forms thereof with at least one candidate inhibitor that potentially specifically binds to a region in said A? -peptide capable of being nitrated, and b) detecting said inhibitor specifically binding to said region in said A? -peptide through detecting a lack of or a reduced aggregation of said at least one A? -peptide. The present invention is further directed at improved methods for treating neuronal degradation and particularly Alzheimer's disease, based on said inhibitor. The present invention is further directed at methods for diagnosing the aggregation of A? -peptide in the context of neuronal degradation and particularly Alzheimer's disease.
    Type: Grant
    Filed: July 12, 2010
    Date of Patent: April 21, 2015
    Assignee: Rheinische Friedrich-Wilhelms-Universität Bonn
    Inventors: Michael Thomas Heneka, Markus Peter Kummer
  • Inhibitors of the Nitration of Amyloid Beta Peptides and Their Uses in the Diagnosis and Treatment of Alzheimer's Disease
    Publication number: 20120192294
    Abstract: The present invention relates to a method for identifying an inhibitor of the aggregation of amyloid-? peptide (A?), comprising the steps of a) contacting at least one A?-peptide and/or the nitrated forms thereof with at least one candidate inhibitor that potentially specifically binds to a region in said A?-peptide capable of being nitrated, and b) detecting said inhibitor specifically binding to said region in said A?-peptide through detecting a lack of or a reduced aggregation of said at least one A?-peptide. The present invention is further directed at improved methods for treating neuronal degradation and particularly Alzheimer's disease, based on said inhibitor. The present invention is further directed at methods for diagnosing the aggregation of A?-peptide in the context of neuronal degradation and particularly Alzheimer's disease.
    Type: Application
    Filed: July 12, 2010
    Publication date: July 26, 2012
    Inventors: Michael Thomas Heneka, Markus Peter Kummer